| Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity S Shen, M Niso-Santano, S Adjemian, T Takehara, SA Malik, H Minoux, ... Molecular cell 48 (5), 667-680, 2012 | 273 | 2012 |
| Cation− π interactions in proteins: can simple models provide an accurate description? H Minoux, C Chipot Journal of the American Chemical Society 121 (44), 10366-10372, 1999 | 240 | 1999 |
| Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study S Shen, O Kepp, M Michaud, I Martins, H Minoux, D Metivier, MC Maiuri, ... Oncogene 30 (45), 4544-4556, 2011 | 188 | 2011 |
| An electrostatic basis for the stability of thermophilic proteins BN Dominy, H Minoux, CL Brooks III Proteins: Structure, Function, and Bioinformatics 57 (1), 128-141, 2004 | 166 | 2004 |
| Machine learning force fields and coarse-grained variables in molecular dynamics: application to materials and biological systems P Gkeka, G Stoltz, A Barati Farimani, Z Belkacemi, M Ceriotti, JD Chodera, ... Journal of chemical theory and computation 16 (8), 4757-4775, 2020 | 161 | 2020 |
| Organophosphorus derivatives of indazoles and use thereof as medicinal products MP Cherrier, F Clerc, A Commercon, P Mailliet, H Minoux, ... US Patent 7,491,710, 2009 | 99 | 2009 |
| Scaffold-constrained molecular generation M Langevin, H Minoux, M Levesque, M Bianciotto Journal of Chemical Information and Modeling 60 (12), 5637-5646, 2020 | 53 | 2020 |
| Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-c]pyridines as Potent Inhibitors of the Hsp90 Molecular … F Vallée, C Carrez, F Pilorge, A Dupuy, A Parent, L Bertin, F Thompson, ... Journal of medicinal chemistry 54 (20), 7206-7219, 2011 | 52 | 2011 |
| Differential water thermodynamics determine PI3K-beta/delta selectivity for solvent-exposed ligand modifications D Robinson, T Bertrand, JC Carry, F Halley, A Karlsson, M Mathieu, ... Journal of Chemical Information and Modeling 56 (5), 886-894, 2016 | 43 | 2016 |
| SAR156497, an exquisitely selective inhibitor of aurora kinases JC Carry, F Clerc, H Minoux, L Schio, J Mauger, A Nair, E Parmantier, ... Journal of medicinal chemistry 58 (1), 362-375, 2015 | 39 | 2015 |
| Fluorene derivatives, composition containing said derivatives and the use thereof P Mailliet, L Bertin, F Thompson, JM Ruxer, F Pilorge, D Benard, ... US Patent 7,674,795, 2010 | 36 | 2010 |
| Structural analysis of the KGD sequence loop of barbourin, an αIIbβ3-specific disintegrin H Minoux, C Chipot, D Brown, B Maigret Journal of Computer-Aided Molecular Design 14, 317-327, 2000 | 27 | 2000 |
| Synthesis of carbohydrate-based peptidomimetics as potential selective fibrinogen receptor antagonists N Moitessier, H Minoux, B Maigret, F Chrétien, Y Chapleu Letters in Peptide Science 5, 75-78, 1998 | 27 | 1998 |
| Hydrazinocarbonyl-thieno [2, 3-C] pyrazoles, process for preparing them, compositions containing them and use thereof C Barberis, JC Carry, G Doerflinger, D Barbalat-damour, F Clerc, ... US Patent 7,595,320, 2009 | 22 | 2009 |
| Substituted thieno [2, 3-c] pyrazoles and their use as medicinal products A Bigot, F Clerc, G Doerflinger, S Mignani, H Minoux US Patent App. 10/900,549, 2005 | 19 | 2005 |
| Tirofiban blocks platelet adhesion to fibrin with minimal perturbation of GpIIb/IIIa structure RR Hantgan, MC Stahle, GW Jerome, C Nagaswami, JW Weisel Thrombosis and haemostasis 87 (05), 910-917, 2002 | 19 | 2002 |
| Contact map fingerprints of protein–ligand unbinding trajectories reveal mechanisms determining residence times computed from scaled molecular dynamics M Bianciotto, P Gkeka, DB Kokh, RC Wade, H Minoux Journal of Chemical Theory and Computation 17 (10), 6522-6535, 2021 | 14 | 2021 |
| Elucidation of a common structure of selective fibrinogen receptor antagonists H Minoux, N Moitessier, Y Chapleur, B Maigret Journal of computer-aided molecular design 12, 533-542, 1998 | 12 | 1998 |
| Pyrazolylbenzimidazole derivatives, compositions containing them and use thereof MP Cherrier, E Parmantier, H Minoux, F Clerc, O Angouillant-Boniface, ... US Patent 9,126,969, 2015 | 10 | 2015 |
| HSP90 inhibitory carbazole derivatives, compositions containing same and use thereof JM Ruxer, V Certal, M Alasia, L Bertin, H Minoux, P Mailliet, F Halley, ... US Patent 8,309,721, 2012 | 10 | 2012 |
Marc BianciottoComputer-Aided Drug Design, SanofiAdresse e-mail validée de sanofi.com
