| Cutaneous TRPV1+ neurons trigger protective innate type 17 anticipatory immunity JA Cohen, TN Edwards, AW Liu, T Hirai, MR Jones, J Wu, Y Li, S Zhang, ... Cell 178 (4), 919-932. e14, 2019 | 230 | 2019 |
| Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes H Nabeshi, T Yoshikawa, K Matsuyama, Y Nakazato, S Tochigi, S Kondoh, ... Particle and fibre toxicology 8, 1-10, 2011 | 195 | 2011 |
| Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application H Nabeshi, T Yoshikawa, K Matsuyama, Y Nakazato, K Matsuo, A Arimori, ... Biomaterials 32 (11), 2713-2724, 2011 | 191 | 2011 |
| Kappa opioid receptor distribution and function in primary afferents LM Snyder, MC Chiang, E Loeza-Alcocer, Y Omori, J Hachisuka, ... Neuron 99 (6), 1274-1288. e6, 2018 | 117 | 2018 |
| Size-dependent cytotoxic effects of amorphous silica nanoparticles on Langerhans cells H Nabeshi, T Yoshikawa, K Matsuyama, Y Nakazato, A Arimori, M Isobe, ... Die Pharmazie-An International Journal of Pharmaceutical Sciences 65 (3 …, 2010 | 111 | 2010 |
| Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages H Nabeshi, T Yoshikawa, A Arimori, T Yoshida, S Tochigi, T Hirai, T Akase, ... Nanoscale research letters 6, 1-6, 2011 | 108 | 2011 |
| Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis S Zhang, TN Edwards, VK Chaudhri, J Wu, JA Cohen, T Hirai, ... Cell 184 (8), 2151-2166. e16, 2021 | 92 | 2021 |
| Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection T Hirai, T Yoshikawa, H Nabeshi, T Yoshida, S Tochigi, K Ichihashi, M Uji, ... Particle and fibre toxicology 9, 1-11, 2012 | 90 | 2012 |
| Competition for active TGFβ cytokine allows for selective retention of antigen-specific tissue-resident memory T cells in the epidermal niche T Hirai, Y Yang, Y Zenke, H Li, VK Chaudhri, S Jacinto, PY Zhou, ... Immunity 54 (1), 84-98. e5, 2021 | 79 | 2021 |
| Metal nanoparticles in the presence of lipopolysaccharides trigger the onset of metal allergy in mice T Hirai, Y Yoshioka, N Izumi, K Ichihashi, T Handa, N Nishijima, E Uemura, ... Nature nanotechnology 11 (9), 808-816, 2016 | 74 | 2016 |
| Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure H Nabeshi, T Yoshikawa, K Matsuyama, Y Nakazato, A Arimori, M Isobe, ... Nanotechnology 23 (4), 045101, 2012 | 73 | 2012 |
| Keratinocyte-mediated activation of the cytokine TGF-β maintains skin recirculating memory CD8+ T cells T Hirai, Y Zenke, Y Yang, L Bartholin, LK Beura, D Masopust, DH Kaplan Immunity 50 (5), 1249-1261. e5, 2019 | 72 | 2019 |
| Intranasal exposure to amorphous nanosilica particles could activate intrinsic coagulation cascade and platelets in mice T Yoshida, Y Yoshioka, S Tochigi, T Hirai, M Uji, K Ichihashi, K Nagano, ... Particle and Fibre Toxicology 10, 1-12, 2013 | 66 | 2013 |
| Intestinal absorption and biological effects of orally administered amorphous silica particles T Yoshida, Y Yoshioka, H Takahashi, K Misato, T Mori, T Hirai, K Nagano, ... Nanoscale research letters 9, 1-7, 2014 | 59 | 2014 |
| Surface modification of amorphous nanosilica particles suppresses nanosilica-induced cytotoxicity, ROS generation, and DNA damage in various mammalian cells T Yoshida, Y Yoshioka, K Matsuyama, Y Nakazato, S Tochigi, T Hirai, ... Biochemical and biophysical research communications 427 (4), 748-752, 2012 | 59 | 2012 |
| Protein corona changes mediated by surface modification of amorphous silica nanoparticles suppress acute toxicity and activation of intrinsic coagulation cascade in mice T Yoshida, Y Yoshioka, Y Morishita, M Aoyama, S Tochigi, T Hirai, ... Nanotechnology 26 (24), 245101, 2015 | 57 | 2015 |
| Allergic responses induced by the immunomodulatory effects of nanomaterials upon skin exposure Y Yoshioka, E Kuroda, T Hirai, Y Tsutsumi, KJ Ishii Frontiers in Immunology 8, 169, 2017 | 56 | 2017 |
| Amorphous silica nanoparticles enhance cross-presentation in murine dendritic cells T Hirai, Y Yoshioka, H Takahashi, K Ichihashi, T Yoshida, S Tochigi, ... Biochemical and biophysical research communications 427 (3), 553-556, 2012 | 52 | 2012 |
| Human scavenger receptor A1-mediated inflammatory response to silica particle exposure is size specific N Nishijima, T Hirai, K Misato, M Aoyama, E Kuroda, KJ Ishii, ... Frontiers in immunology 8, 379, 2017 | 44 | 2017 |
| CD301b+ dendritic cells suppress T follicular helper cells and antibody responses to protein antigens Y Kumamoto, T Hirai, PW Wong, DH Kaplan, A Iwasaki elife 5, e17979, 2016 | 43 | 2016 |
