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Kimberly J. McCabe
Kimberly J. McCabe
Verified email at simula.no
Title
Cited by
Cited by
Year
Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin
JD Powers, CC Yuan, KJ McCabe, JD Murray, MC Childers, GV Flint, ...
Proceedings of the National Academy of Sciences 116 (23), 11502-11507, 2019
372019
Contributions of Ca2+-independent thin filament activation to cardiac muscle function
Y Aboelkassem, JA Bonilla, KJ McCabe, SG Campbell
Biophysical Journal 109 (10), 2101-2112, 2015
312015
Molecular Effects of cTnC DCM Mutations on Calcium Sensitivity and Myofilament Activation An Integrated Multiscale Modeling Study
S Dewan, KJ McCabe, M Regnier, AD McCulloch, S Lindert
The Journal of Physical Chemistry B 120 (33), 8264-8275, 2016
212016
Computational modeling approaches to cAMP/PKA signaling in cardiomyocytes
KJ McCabe, P Rangamani
Journal of molecular and cellular cardiology 154, 32-40, 2021
112021
A stochastic multiscale model of cardiac thin filament activation using Brownian-Langevin dynamics
Y Aboelkassem, KJ McCabe, GA Huber, M Regnier, JA McCammon, ...
Biophysical journal 117 (12), 2255-2272, 2019
102019
Multiscale models of cardiac muscle biophysics and tissue remodeling in hypertrophic cardiomyopathies
Y Aboelkassem, JD Powers, KJ McCabe, AD McCulloch
Current opinion in biomedical engineering 11, 35-44, 2019
92019
Insights and challenges of multi-scale modeling of sarcomere mechanics in cTn and tm DCM mutants—genotype to cellular phenotype
S Dewan, KJ McCabe, M Regnier, AD McCulloch
Frontiers in Physiology 8, 240453, 2017
92017
Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks
MH Mesa, J van den Brink, WE Louch, KJ McCabe, P Rangamani
Biophysical Journal 121 (3), 378a, 2022
7*2022
Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere
KJ McCabe, Y Aboelkassem, AE Teitgen, GA Huber, JA McCammon, ...
Archives of biochemistry and biophysics 695, 108582, 2020
62020
Turning the azimuthal motions of adjacent tropomyosins into a coupled n-body problem in a brownian model of cardiac thin filament activation
Y Aboelkassem, KJ McCabe, G Huber, J Sundnes, AD McCulloch
Biophysical Journal 114 (3), 502a-503a, 2018
52018
Investigating the Multiscale Impact of Deoxyadenosine Triphosphate (dATP) on Pulmonary Arterial Hypertension (PAH) Induced Heart Failure
K Garcia, M Hock, V Jaltare, C Uysalel, KJ McCabe, A Teitgen, ...
Computational Physiology: Simula Summer School 2021− Student Reports, 77-90, 2022
12022
Exploring the effects of 2. deoxy-atp on serca 2a using multiscale modeling
KJ McCabe, SP Hirakis, AE Teitgen, AB Duclos, M Regnier, RE Amaro, ...
Biophysical Journal 118 (3), 260a, 2020
12020
Molecular effects of cardiac troponin DCM mutations on calcium sensitivity and Myofilament activation-an integrated multi-scale modeling study
S Dewan, K McCabe, M Regnier, A McCulloch, S Lindert
Biophysical Journal 112 (3), 322a, 2017
12017
Spine apparatus modulates Ca2+ in spines through spatial localization of sources and sinks
MH Mesa, G Garcia, F Hoerndli, KJ McCabe, P Rangamani
Biophysical Journal 123 (3), 415a, 2024
2024
Computational Physiology: Simula Summer School 2023− Student Reports
KJ McCabe
Springer Nature, 2024
2024
Spine apparatus modulates Ca2+ in spines through spatial localization of sources and sinks
GC Garcia, F Hoerndli, KJ McCabe, P Rangamani
2023
Multiscale computational modeling of the effects of 2’-deoxy-ATP on cardiac muscle calcium handling
MT Hock, AE Teitgen, KJ McCabe, SP Hirakis, GA Huber, M Regnier, ...
Journal of Applied Physics 134 (7), 2023
2023
Multiscale simulations of the effects of 2’-deoxy-ATP and a myosin mutation on actomyosin interactions
M Hock, MC Childers, AE Teitgen, G Huber, KJ McCabe, JA McCammon, ...
Biophysical Journal 121 (3), 291a, 2022
2022
2-Deoxy-ATP improves ventricular function via combined effects on myosin recruitment from the super-relaxed state, crossbridge cycling and calcium dynamics in healthy and …
AE Teitgen, KJ McCabe, M Hock, DA Beard, M Regnier, AD McCulloch
Biophysical Journal 121 (3), 435a, 2022
2022
A Coupled Electromechanical Myocyte Model to Assess the Effects of 2‐deoxy‐ATP on Contractile Function in the Heart
A Teitgen, K McCabe, M Hock, M Regnier, A McCulloch
The FASEB Journal 34 (S1), 1-1, 2020
2020
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