SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability SX Pfister, S Ahrabi, LP Zalmas, S Sarkar, F Aymard, CZ Bachrati, ... Cell reports 7 (6), 2006-2018, 2014 | 453 | 2014 |
Inhibiting WEE1 selectively kills histone H3K36me3-deficient cancers by dNTP starvation SX Pfister, E Markkanen, Y Jiang, S Sarkar, M Woodcock, G Orlando, ... Cancer cell 28 (5), 557-568, 2015 | 295 | 2015 |
Atypical E2F activity restrains APC/CCCS52A2 function obligatory for endocycle onset T Lammens, V Boudolf, L Kheibarshekan, L Panagiotis Zalmas, ... Proceedings of the National Academy of Sciences 105 (38), 14721-14726, 2008 | 199 | 2008 |
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer N Kanu, MA Cerone, G Goh, LP Zalmas, J Bartkova, M Dietzen, ... Genome biology 17, 1-15, 2016 | 171 | 2016 |
Arginine methylation-dependent reader-writer interplay governs growth control by E2F-1 S Zheng, J Moehlenbrink, YC Lu, LP Zalmas, CA Sagum, S Carr, ... Molecular cell 52 (1), 37-51, 2013 | 163 | 2013 |
DNA‐damage response control of E2F7 and E2F8 L Panagiotis Zalmas, X Zhao, AL Graham, R Fisher, C Reilly, AS Coutts, ... EMBO reports 9 (3), 252-259, 2008 | 152 | 2008 |
The PROTACtable genome M Schneider, CJ Radoux, A Hercules, D Ochoa, I Dunham, LP Zalmas, ... Nature reviews Drug discovery 20 (10), 789-797, 2021 | 131 | 2021 |
A transcription cofactor required for the heat‐shock response D Xu, LP Zalmas, NB La Thangue EMBO reports 9 (7), 662-669, 2008 | 88 | 2008 |
Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution S Venkatesan, M Angelova, C Puttick, H Zhai, DR Caswell, WT Lu, ... Cancer discovery 11 (10), 2456-2473, 2021 | 86 | 2021 |
Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor SM Carr, S Munro, LP Zalmas, O Fedorov, C Johansson, T Krojer, ... Proceedings of the National Academy of Sciences 111 (31), 11341-11346, 2014 | 52 | 2014 |
Cyclin D mediates tolerance of genome-doubling in cancers with functional p53 A Crockford, LP Zalmas, E Grönroos, SM Dewhurst, N McGranahan, ... Annals of Oncology 28 (1), 149-156, 2017 | 48 | 2017 |
A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest K Deiss, N Lockwood, M Howell, HA Segeren, RE Saunders, ... Nucleic acids research 47 (6), 2906-2921, 2019 | 26 | 2019 |
E2F-7 couples DNA damage-dependent transcription with the DNA repair process LP Zalmas, A Coutts, T Helleday, NB La Thangue Cell Cycle 12 (18), 3037-3051, 2013 | 24 | 2013 |
A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization C Pacini, E Duncan, E Gonçalves, J Gilbert, S Bhosle, S Horswell, ... Cancer Cell, 2024 | 5 | 2024 |
Illuminating the druggable genome through patent bioactivity data MP Magariños, A Gaulton, E Félix, T Kiziloren, R Arcila, TI Oprea, ... PeerJ 11, e15153, 2023 | 5 | 2023 |
An emerging regulatory network of NHEJ via DYNLL1-mediated 53BP1 redistribution LP Zalmas, WT Lu, N Kanu Annals of Translational Medicine 7 (Suppl 3), 2019 | 2 | 2019 |
Genetic interaction library screening with a next-generation dual guide CRISPR system T Burgold, E Karakoc, E Goncalves, L Dwane, I Barrio-Hernandez, ... bioRxiv, 2024.03. 28.587052, 2024 | | 2024 |
Integrated systems biology approach identifies gene targets for endothelial dysfunction I Pinheiro‐de‐Sousa, MH Fonseca‐Alaniz, G Giudice, IC Valadão, ... Molecular Systems Biology 19 (12), e11462, 2023 | | 2023 |
Abstract LB237: Functional characterisation of TRACERx reveals mechanisms of NSCLC evolution WT Lu, LP Zalmas, C Bailey, O Pich, CM Ruiz, J Black, G Stavrou, ... Cancer Research 83 (8_Supplement), LB237-LB237, 2023 | | 2023 |
TRACERx: Intra-tumor subclonal driver mutation results in defective DNA damage response (DDR) and genome instability W Lu, LP Zalmas, T Webber, N Kanu, C Swanton Cancer Research 79 (13_Supplement), 2567-2567, 2019 | | 2019 |