| Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation T Visnes, A Cázares-Körner, W Hao, O Wallner, G Masuyer, O Loseva, ... Science 362 (6416), 834-839, 2018 | 192 | 2018 |
| A general and convergent synthesis of diverse glycosylphosphatidylinositol glycolipids YH Tsai, S Götze, I Vilotijevic, M Grube, DV Silva, PH Seeberger Chemical Science 4 (1), 468-481, 2013 | 53 | 2013 |
| Targeting BER enzymes in cancer therapy T Visnes, M Grube, BMF Hanna, C Benitez-Buelga, A Cázares-Körner, ... DNA repair 71, 118-126, 2018 | 52 | 2018 |
| Target 2035–update on the quest for a probe for every protein S Müller, S Ackloo, A Al Chawaf, B Al-Lazikani, A Antolin, JB Baell, ... RSC Medicinal Chemistry 13 (1), 13-21, 2022 | 41 | 2022 |
| Targeting OGG1 arrests cancer cell proliferation by inducing replication stress T Visnes, C Benítez-Buelga, A Cázares-Körner, K Sanjiv, BMF Hanna, ... Nucleic acids research 48 (21), 12234-12251, 2020 | 41 | 2020 |
| 19F NMR-Guided Design of Glycomimetic Langerin Ligands EC Wamhoff, J Hanske, L Schnirch, J Aretz, M Grube, D Varón Silva, ... ACS Chemical Biology 11 (9), 2407-2413, 2016 | 36 | 2016 |
| Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress N Bonagas, NMS Gustafsson, M Henriksson, P Marttila, R Gustafsson, ... Nature cancer 3 (2), 156-172, 2022 | 30 | 2022 |
| Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects JM Baquero, C Benítez-Buelga, V Rajagopal, Z Zhenjun, R Torres-Ruiz, ... Scientific reports 11 (1), 3490, 2021 | 26 | 2021 |
| Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function M Michel, C Benitez-Buelga, PA Calvo, BMF Hanna, O Mortusewicz, ... Science 376 (6600), 1471-1476, 2022 | 25 | 2022 |
| In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization M Michel, EJ Homan, E Wiita, K Pedersen, I Almlöf, AL Gustavsson, ... Frontiers in Chemistry 8, 443, 2020 | 23 | 2020 |
| Computational and experimental druggability assessment of human DNA glycosylases M Michel, T Visnes, EJ Homan, B Seashore-Ludlow, M Hedenström, ... ACS omega 4 (7), 11642-11656, 2019 | 23 | 2019 |
| NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487 BMF Hanna, M Michel, T Helleday, O Mortusewicz International Journal of Molecular Sciences 22 (9), 4542, 2021 | 14 | 2021 |
| Glycosylphosphatidylinositols of protozoan parasites YH Tsai, M Grube, PH Seeberger, D Varon Silva Trends Glycosci. Glycotechnol 24 (140), 231-243, 2012 | 12 | 2012 |
| Synthesis of Galactosylated Glycosylphosphatidylinositol Derivatives from Trypanosoma brucei M Grube, BY Lee, M Garg, D Michel, I Vilotijević, A Malik, PH Seeberger, ... Chemistry–A European Journal 24 (13), 3271-3282, 2018 | 11 | 2018 |
| Assembly and application of a low budget photoreactor O Wallner, K Mamonov, F Ortis, D Michel, M Michel Chemistry‐Methods 1 (5), 240-244, 2021 | 5 | 2021 |
| Nudix hydrolase 18 catalyzes the hydrolysis of active triphosphate metabolites of the antivirals remdesivir, ribavirin, and molnupiravir AS Jemth, ER Scaletti, E Homan, P Stenmark, T Helleday, M Michel Journal of Biological Chemistry 298 (8), 2022 | 3 | 2022 |
| Compound absorption in polymer devices impairs the translatability of preclinical safety assessments AM Kemas, R Zandi Shafagh, N Taebnia, M Michel, L Preiss, U Hofmann, ... Advanced Healthcare Materials, 2303561, 2023 | 2 | 2023 |
| Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel SM Zhang, CBJ Paulin, H Shu, M Yagüe-Capilla, M Michel, P Marttila, ... Iscience 27 (2), 2024 | 1 | 2024 |
| Optimization of N‐Piperidinyl‐Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8‐Oxo‐Guanine DNA Glycosylase 1 O Wallner, A Cázares‐Körner, ER Scaletti, G Masuyer, T Bekkhus, ... ChemMedChem 18 (1), e202200310, 2023 | 1 | 2023 |
| Target 2035–an update on private sector contributions S Ackloo, AA Antolin, JM Bartolome, H Beck, A Bullock, UAK Betz, ... RSC Medicinal Chemistry 14 (6), 1002-1011, 2023 | 1 | 2023 |
