| An allosteric modulator to control endogenous G protein-coupled receptors with light S Pittolo, X Gómez-Santacana, K Eckelt, X Rovira, J Dalton, C Goudet, ... Nature chemical biology 10 (10), 813-815, 2014 | 169 | 2014 |
| Illuminating phenylazopyridines to photoswitch metabotropic glutamate receptors: from the flask to the animals X Gómez-Santacana, S Pittolo, X Rovira, M Lopez, C Zussy, JAR Dalton, ... ACS central science 3 (1), 81-91, 2017 | 75 | 2017 |
| Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4 C Zussy, X Gómez-Santacana, X Rovira, D De Bundel, S Ferrazzo, ... Molecular psychiatry 23 (3), 509-520, 2018 | 63 | 2018 |
| Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations C Nasrallah, G Cannone, J Briot, K Rottier, AE Berizzi, CY Huang, ... Cell reports 36 (9), 2021 | 36 | 2021 |
| Photoswitching the Efficacy of a Small‐Molecule Ligand for a Peptidergic GPCR: from Antagonism to Agonism X Gómez‐Santacana, SM de Munnik, P Vijayachandran, ... Angewandte Chemie 130 (36), 11782-11786, 2018 | 36 | 2018 |
| Computational analysis of negative and positive allosteric modulator binding and function in metabotropic glutamate receptor 5 (in) activation JAR Dalton, X Gomez-Santacana, A Llebaria, J Giraldo Journal of chemical information and modeling 54 (5), 1476-1487, 2014 | 29 | 2014 |
| A toolbox of molecular photoswitches to modulate the CXCR3 chemokine receptor with light X Gómez-Santacana, SM De Munnik, TAM Mocking, NJ Hauwert, S Sun, ... Beilstein Journal of Organic Chemistry 15 (1), 2509-2523, 2019 | 20 | 2019 |
| Shining light on an mGlu5 photoswitchable NAM: a theoretical perspective J AR Dalton, I Lans, X Rovira, F Malhaire, X Gómez-Santacana, S Pittolo, ... Current neuropharmacology 14 (5), 441-454, 2016 | 19 | 2016 |
| Reversible silencing of endogenous receptors in intact brain tissue using 2-photon pharmacology S Pittolo, H Lee, A Lladó, S Tosi, M Bosch, L Bardia, X Gómez-Santacana, ... Proceedings of the National Academy of Sciences 116 (27), 13680-13689, 2019 | 18 | 2019 |
| Mechanistic insights into light-driven allosteric control of GPCR biological activity M Ricart-Ortega, AE Berizzi, V Pereira, F Malhaire, J Catena, J Font, ... ACS Pharmacology & Translational Science 3 (5), 883-895, 2020 | 13 | 2020 |
| Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5 negative allosteric modulation X Gómez-Santacana, JAR Dalton, X Rovira, JP Pin, C Goudet, ... European Journal of Medicinal Chemistry 127, 567-576, 2017 | 12 | 2017 |
| A double effect molecular switch leads to a novel potent negative allosteric modulator of metabotropic glutamate receptor 5 X Gomez-Santacana, X Rovira, JA Dalton, C Goudet, JP Pin, P Gorostiza, ... MedChemComm 5 (10), 1548-1554, 2014 | 12 | 2014 |
| Photoswitchable allosteric modulators for metabotropic glutamate receptors X Gómez-Santacana, S Panarello, X Rovira, A Llebaria Current opinion in pharmacology 66, 102266, 2022 | 8 | 2022 |
| Photopharmacology of G‐Protein‐Coupled Receptors S Panarello, X Rovira, A Llebaria, X Gómez‐Santacana Molecular Photoswitches: Chemistry, Properties, and Applications 2, 921-944, 2022 | 4 | 2022 |
| Reversible silencing of endogenous receptors in intact brain tissue using two-photon pharmacology S Pittolo, H Lee, A Lladó, S Tosi, M Bosch, L Bardia, X Gómez-Santacana, ... bioRxiv, 515288, 2019 | 2 | 2019 |
| Optical activation of endogenous metabotropic glutamate receptor 4 (mGlu4) in the amygdala dynamically regulates symptoms associated with persistent inflammatory pain C Zussy, X Gómez-Santacana, X Rovira, D De Bundel, S Ferrazzo, ... Molecular Psychiatry 23 (3), 489-489, 2018 | 2 | 2018 |
| Control of Theta Oscillatory Activity Underlying Fear Expression by mGlu5 Receptors P Matulewicz, A Ramos-Prats, X Gómez-Santacana, A Llebaria, ... Cells 11 (22), 3555, 2022 | 1 | 2022 |
| El nacimiento de la fotofarmacología XR Algans, XG Santacana Investigación y ciencia, 30-35, 2019 | 1 | 2019 |
| Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4 C Zussy, X Gomez-Santacana, X Rovira, D De Bundel, S Ferrazo, ... FUNDAMENTAL & CLINICAL PHARMACOLOGY 31, 59-59, 2017 | 1 | 2017 |
| Optical Control of Adenosine A2A Receptor Using Istradefylline Photosensitivity A Dumazer, X Gómez-Santacana, F Malhaire, C Jopling, D Maurel, ... ACS chemical neuroscience, 2024 | | 2024 |
