| Identification of a novel endocannabinoid-hydrolyzing enzyme expressed by microglial cells GG Muccioli, C Xu, E Odah, E Cudaback, JA Cisneros, DM Lambert, ... Journal of Neuroscience 27 (11), 2883-2889, 2007 | 190 | 2007 |
| The constitutive production of the endocannabinoid 2‐arachidonoylglycerol participates in oligodendrocyte differentiation O Gomez, A Arevalo‐Martin, D Garcia‐Ovejero, S Ortega‐Gutierrez, ... Glia 58 (16), 1913-1927, 2010 | 108 | 2010 |
| Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor P Dziedzic, JA Cisneros, MJ Robertson, AA Hare, NE Danford, ... Journal of the American Chemical Society 137 (8), 2996-3003, 2015 | 81 | 2015 |
| Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography AH Chan, WG Lee, KA Spasov, JA Cisneros, SN Kudalkar, ZO Petrova, ... Proceedings of the National Academy of Sciences 114 (36), 9725-9730, 2017 | 55 | 2017 |
| Crystal structures of HIV-1 reverse transcriptase with picomolar inhibitors reveal key interactions for drug design KM Frey, M Bollini, AC Mislak, JA Cisneros, R Gallardo-Macias, ... Journal of the American Chemical Society 134 (48), 19501-19503, 2012 | 55 | 2012 |
| Dual inhibition of α/β-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons WR Marrs, EA Horne, S Ortega-Gutierrez, JA Cisneros, C Xu, YH Lin, ... Journal of Biological Chemistry 286 (33), 28723-28728, 2011 | 46 | 2011 |
| The medicinal chemistry of agents targeting monoacylglycerol lipase S Ortega-Gutierrez, A Viso, JA Cisneros Current Topics in Medicinal Chemistry 8 (3), 231-246, 2008 | 43 | 2008 |
| Structure–activity relationship of a new Series of reversible dual monoacylglycerol lipase/fatty acid amide hydrolase inhibitors JA Cisneros, E Bjorklund, I Gonzalez-Gil, Y Hu, A Canales, FJ Medrano, ... Journal of Medicinal Chemistry 55 (2), 824-836, 2012 | 42 | 2012 |
| Systematic study of effects of structural modifications on the aqueous solubility of drug-like molecules JA Cisneros, MJ Robertson, BQ Mercado, WL Jorgensen ACS medicinal chemistry letters 8 (1), 124-127, 2017 | 41 | 2017 |
| A fluorescence polarization assay for binding to macrophage migration inhibitory factor and crystal structures for complexes of two potent inhibitors JA Cisneros, MJ Robertson, M Valhondo, WL Jorgensen Journal of the American Chemical Society 138 (27), 8630-8638, 2016 | 40 | 2016 |
| Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility M Bollini, JA Cisneros, KA Spasov, KS Anderson, WL Jorgensen Bioorganic & medicinal chemistry letters 23 (18), 5213-5216, 2013 | 39 | 2013 |
| Extension into the entrance channel of HIV-1 reverse transcriptase—Crystallography and enhanced solubility M Bollini, KM Frey, JA Cisneros, KA Spasov, K Das, JD Bauman, E Arnold, ... Bioorganic & medicinal chemistry letters 23 (18), 5209-5212, 2013 | 39 | 2013 |
| From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection SN Kudalkar, J Beloor, E Quijano, KA Spasov, WG Lee, JA Cisneros, ... Proceedings of the National Academy of Sciences 115 (4), E802-E811, 2018 | 34 | 2018 |
| JAK2 JH2 fluorescence polarization assay and crystal structures for complexes with three small molecules AS Newton, L Deiana, DE Puleo, JA Cisneros, KJ Cutrona, J Schlessinger, ... ACS medicinal chemistry letters 8 (6), 614-617, 2017 | 33 | 2017 |
| Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase–dihydrofolate reductase VP Kumar, JA Cisneros, KM Frey, A Castellanos-Gonzalez, Y Wang, ... Bioorganic & medicinal chemistry letters 24 (17), 4158-4161, 2014 | 32 | 2014 |
| Irregularities in enzyme assays: The case of macrophage migration inhibitory factor JA Cisneros, MJ Robertson, M Valhondo, WL Jorgensen Bioorganic & Medicinal Chemistry Letters 26 (12), 2764-2767, 2016 | 25 | 2016 |
| Optimization of pyrazoles as phenol surrogates to yield potent inhibitors of macrophage migration inhibitory factor V Trivedi‐Parmar, MJ Robertson, JA Cisneros, SG Krimmer, ... ChemMedChem 13 (11), 1092-1097, 2018 | 21 | 2018 |
| Structure− Activity Relationship of a Series of Inhibitors of Monoacylglycerol Hydrolysis Comparison with Effects upon Fatty Acid Amide Hydrolase JA Cisneros, S Vandevoorde, S Ortega-Gutiérrez, C Paris, CJ Fowler, ... Journal of medicinal chemistry 50 (20), 5012-5023, 2007 | 18 | 2007 |
| Covalent inhibition of wild-type HIV-1 reverse transcriptase using a fluorosulfate warhead JA Ippolito, H Niu, N Bertoletti, ZJ Carter, S Jin, KA Spasov, JA Cisneros, ... ACS Medicinal Chemistry Letters 12 (2), 249-255, 2021 | 17 | 2021 |
| Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV SN Kudalkar, I Ullah, N Bertoletti, HK Mandl, JA Cisneros, J Beloor, ... Antiviral research 167, 110-116, 2019 | 17 | 2019 |
