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Shion A. Lim
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Year
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2
A Glasgow, J Glasgow, D Limonta, P Solomon, I Lui, Y Zhang, MA Nix, ...
Proceedings of the National Academy of Sciences 117 (45), 28046-28055, 2020
2382020
The thermostability and specificity of ancient proteins
LC Wheeler, SA Lim, S Marqusee, MJ Harms
Current opinion in structural biology 38, 37-43, 2016
1372016
Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection
SK Elledge, XX Zhou, JR Byrnes, AJ Martinko, I Lui, K Pance, SA Lim, ...
Nature biotechnology 39 (8), 928-935, 2021
1322021
Illumination of growth, division and secretion by metabolic labeling of the bacterial cell surface
MS Siegrist, BM Swarts, DM Fox, SA Lim, CR Bertozzi
FEMS microbiology reviews 39 (2), 184-202, 2015
1302015
Visualizing Attack of Escherichia coli by the Antimicrobial Peptide Human Defensin 5
HR Chileveru, SA Lim, P Chairatana, AJ Wommack, IL Chiang, EM Nolan
Biochemistry 54 (9), 1767-1777, 2015
1042015
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2
CJ Bracken, SA Lim, P Solomon, NJ Rettko, DP Nguyen, BS Zha, ...
Nature chemical biology 17 (1), 113-121, 2021
922021
Engineering interferons and interleukins for cancer immunotherapy
PG Holder, SA Lim, CS Huang, P Sharma, YS Dagdas, B Bulutoglu, ...
Advanced drug delivery reviews 182, 114112, 2022
692022
Competitive SARS-CoV-2 serology reveals most antibodies targeting the spike receptor-binding domain compete for ACE2 binding
JR Byrnes, XX Zhou, I Lui, SK Elledge, JE Glasgow, SA Lim, ...
MSphere 5 (5), 10.1128/msphere. 00802-20, 2020
67*2020
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2
AJ Samelson, QD Tran, R Robinot, L Carrau, VV Rezelj, AM Kain, M Chen, ...
Nature cell biology 24 (1), 24-34, 2022
64*2022
Evolutionary trend toward kinetic stability in the folding trajectory of RNases H
SA Lim, KM Hart, MJ Harms, S Marqusee
Proceedings of the National Academy of Sciences 113 (46), 13045-13050, 2016
402016
Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with limited intra-Spike avidity
I Lui, XX Zhou, SA Lim, SK Elledge, P Solomon, NJ Rettko, BS Zha, ...
BioRxiv, 2020.05. 21.109157, 2020
362020
Theranostic targeting of CUB domain containing protein 1 (CDCP1) in pancreatic cancer
A Moroz, YH Wang, JM Sharib, J Wei, N Zhao, Y Huang, Z Chen, ...
Clinical Cancer Research 26 (14), 3608-3615, 2020
292020
Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing Spike epitopes demonstrate enhanced potency against SARS-CoV-2
SA Lim, JA Gramespacher, K Pance, NJ Rettko, P Solomon, J Jin, I Lui, ...
MAbs 13 (1), 1893426, 2021
262021
Tracing a protein’s folding pathway over evolutionary time using ancestral sequence reconstruction and hydrogen exchange
SA Lim, ER Bolin, S Marqusee
Elife 7, e38369, 2018
262018
Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers
SA Lim, J Zhou, AJ Martinko, YH Wang, EV Filippova, V Steri, D Wang, ...
The Journal of clinical investigation 132 (4), 2022
182022
CUB domain-containing protein 1 (CDCP1) is a target for radioligand therapy in castration-resistant prostate cancer, including PSMA null disease
N Zhao, S Chopra, K Trepka, YH Wang, S Sakhamuri, N Hooshdaran, ...
Clinical Cancer Research 28 (14), 3066-3075, 2022
112022
Serial non-invasive monitoring of renal disease following immune-mediated injury using near-infrared optical imaging
Y Du, S An, L Liu, L Li, XJ Zhou, RP Mason, C Mohan
Public Library of Science 7 (9), e43941, 2012
112012
The burst‐phase folding intermediate of ribonuclease H changes conformation over evolutionary history
SA Lim, S Marqusee
Biopolymers 109 (8), e23086, 2018
102018
Split enzymes: Design principles and strategy
SA Lim, JA Wells
Methods in Enzymology 644, 275-296, 2020
92020
Exploring the evolutionary history of kinetic stability in the α-lytic protease family
CF Nixon, SA Lim, ZR Sailer, IN Zheludev, CL Gee, BA Kelch, MJ Harms, ...
Biochemistry 60 (3), 170-181, 2021
42021
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Articles 1–20