Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2 JO Early, D Menon, CA Wyse, MP Cervantes-Silva, Z Zaslona, RG Carroll, ... Proceedings of the National Academy of Sciences 115 (36), E8460-E8468, 2018 | 276 | 2018 |
PRC2. 1 and PRC2. 2 synergize to coordinate H3K27 trimethylation E Healy, M Mucha, E Glancy, DJ Fitzpatrick, E Conway, HK Neikes, ... Molecular cell 76 (3), 437-452. e6, 2019 | 158 | 2019 |
The H3K36me2 methyltransferase Nsd1 demarcates PRC2-mediated H3K27me2 and H3K27me3 domains in embryonic stem cells G Streubel, A Watson, SG Jammula, A Scelfo, DJ Fitzpatrick, G Oliviero, ... Molecular cell 70 (2), 371-379. e5, 2018 | 156 | 2018 |
A family of vertebrate-specific polycombs encoded by the LCOR/LCORL genes balance PRC2 subtype activities E Conway, E Jerman, E Healy, S Ito, D Holoch, G Oliviero, O Deevy, ... Molecular cell 70 (3), 408-421. e8, 2018 | 136 | 2018 |
Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal G Streubel, DJ Fitzpatrick, G Oliviero, A Scelfo, B Moran, S Das, ... The EMBO journal 36 (15), 2216-2232, 2017 | 46 | 2017 |
Simultaneous disruption of PRC2 and enhancer function underlies histone H3. 3-K27M oncogenic activity in human hindbrain neural stem cells GL Brien, RB Bressan, C Monger, D Gannon, E Lagan, AM Doherty, ... Nature Genetics 53 (8), 1221-1232, 2021 | 38 | 2021 |
Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast CP Young, C Hillyer, K Hokamp, DJ Fitzpatrick, NK Konstantinov, ... BMC genomics 18, 1-18, 2017 | 34 | 2017 |
The Candida albicans TOR-activating GTPases Gtr1 and Rhb1 coregulate starvation responses and biofilm formation PR Flanagan, NN Liu, DJ Fitzpatrick, K Hokamp, JR Köhler, GP Moran Msphere 2 (6), 10.1128/msphere. 00477-17, 2017 | 28 | 2017 |
HGDP and HapMap analysis by Ancestry Mapper reveals local and global population relationships TR Magalhães, JP Casey, J Conroy, R Regan, DJ Fitzpatrick, N Shah, ... PLoS One 7 (11), e49438, 2012 | 18 | 2012 |
Genome-wide epistatic expression quantitative trait loci discovery in four human tissues reveals the importance of local chromosomal interactions governing gene expression DJ Fitzpatrick, CJ Ryan, N Shah, D Greene, C Molony, DC Shields BMC genomics 16, 1-13, 2015 | 8 | 2015 |
Discovering anti-platelet drug combinations with an integrated model of activator-inhibitor relationships, activator-activator synergies and inhibitor-inhibitor synergies F Lombardi, K Golla, DJ Fitzpatrick, FP Casey, N Moran, DC Shields PLoS Computational Biology 11 (4), e1004119, 2015 | 3 | 2015 |
Epidemiology of constipation and its associated factors in an ageing population of people with an intellectual disability in Ireland: A cross-sectional study DJ Fitzpatrick, P McCallion, M McCarron, EA Burke Journal of Intellectual & Developmental Disability, 1-9, 2023 | | 2023 |
Multimorbidity and Physical Health Trajectories in People with Intellectual Disability E Burke, P Pavithra, F O’Brien, D Fitzpatrick, S Corrigan, C Ryan, M Haigh, ... Longitudinal Dynamics in the Ageing of People with an Intellectual …, 2023 | | 2023 |
DISCOVERY OF NEUROPSYCHIATRIC DISEASE SNPs AFFECTING BRAIN TRANS-GENE EXPRESSION M O Duill, DJ Fitzpatrick, D Shields IRISH JOURNAL OF MEDICAL SCIENCE 184, 554-554, 2015 | | 2015 |