| Novel pyrimidinone derivatives: synthesis, antitumor and antimicrobial evaluation AT Taher, AA Helwa Chemical and Pharmaceutical Bulletin 60 (4), 521-530, 2012 | 31 | 2012 |
| Novel antiproliferative agents bearing morpholinopyrimidine scaffold as PI3K inhibitors and apoptosis inducers; design, synthesis and molecular docking AA Helwa, NM El-Dydamony, RA Radwan, SM Abdelraouf, ... Bioorganic Chemistry 102, 104051, 2020 | 24 | 2020 |
| Synthesis and biological evaluation of novel pyrimidine-5-carbonitriles featuring morpholine moiety as antitumor agents AA Helwa, EM Gedawy, AT Taher, AK ED El-Ansary, SM Abou-Seri Future Medicinal Chemistry 12 (5), 403-421, 2019 | 17 | 2019 |
| Pyrimidine-5-carbonitrile based potential anticancer agents as apoptosis inducers through PI3K/AKT axis inhibition in leukaemia K562 NM El-Dydamony, RM Abdelnaby, R Abdelhady, O Ali, MI Fahmy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 895-911, 2022 | 14 | 2022 |
| Synthesis and bioactivity evaluation of new pyrimidinone-5-carbonitriles as potential anticancer and antimicrobial agents AA Helwa, EM Gedawy, SM Abou-Seri, AT Taher, AK El-Ansary Research on Chemical Intermediates 44, 2685-2702, 2018 | 14 | 2018 |
| Synthesis, antitumor and antimicrobial testing of some new thiopyrimidine analogues AT Taher, AA Helwa Chemical and Pharmaceutical Bulletin 60 (10), 1305-1313, 2012 | 11 | 2012 |
| Coumarin-acetohydrazide derivatives as novel antiproliferative agents via VEGFR-2/AKT axis inhibition and apoptosis triggering LMAA Ghany, NM El-Dydamony, AA Helwa, SM Abdelraouf, ... New Journal of Chemistry 46 (36), 17394-17409, 2022 | 7 | 2022 |
| Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives as novel anti-cancer, dual EGFR WT/COX-2 inhibitors with docking studies N Reda, A Elshewy, HI El-Askary, KO Mohamed, AA Helwa RSC advances 13 (46), 32296-32320, 2023 | 4 | 2023 |
| Novel pyrazolo [3, 4-d] pyrimidine derivatives: design, synthesis, anticancer evaluation, VEGFR-2 inhibition, and antiangiogenic activity AM Abdelhamed, RA Hassan, HH Kadry, AA Helwa RSC Medicinal Chemistry 14 (12), 2640-2657, 2023 | 1 | 2023 |
| Novel Pyrimidine-5-Carbonitriles as potential apoptotic and antiproliferative agents by dual inhibition of EGFRWT/T790M and PI3k enzymes; Design, Synthesis, biological … N Reda, KO Mohamed, K Abdou, AA Helwa, A Elshewy Bioorganic Chemistry, 107185, 2024 | | 2024 |
| Design, synthesis and biological evaluation of novel morpholinopyrimidine-5-carbonitrile derivatives as dual PI3K/mTOR inhibitors GS Rady, MA El Deeb, MTM Sarg, AT Taher, AA Helwa RSC Medicinal Chemistry 15 (2), 733-752, 2024 | | 2024 |
| Pyrimidine Derivatives as Anticancer Agents AA Helwa, NM Ryad, A Youssef, YM Omar, KM Attia, AAS El Etrawy Journal of Pharmaceutical Sciences and Drug Manufacturing 1 (1), 54-68, 2024 | | 2024 |
| Imidazo-and pyrazolopyrimidine scaffolds as anticancer agents GS Rady, MA El Deeb, M Sarg, AT Shalaby, AA Helwa Azhar International Journal of Pharmaceutical and Medical Sciences 4 (1 …, 2024 | | 2024 |
| Design and Synthesis of 5-cyano-6-substituted phenyl-2-thiouracil derivatives as anticancer and antimicrobial agents AAAM Helwa Cairo University, 2012 | | 2012 |
