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Anthony J. Covarrubias, PhD
Anthony J. Covarrubias, PhD
Assistant Professor. UCLA David Geffen School of Medicine and Division of Life Sciences
Verified email at mednet.ucla.edu
Title
Cited by
Cited by
Year
NAD+ metabolism and its roles in cellular processes during ageing
AJ Covarrubias, R Perrone, A Grozio, E Verdin
Nature reviews Molecular cell biology 22 (2), 119-141, 2021
7202021
The TSC-mTOR pathway regulates macrophage polarization
V Byles, AJ Covarrubias, I Ben-Sahra, DW Lamming, DM Sabatini, ...
Nature communications 4 (1), 2834, 2013
5692013
Ketogenic diet reduces midlife mortality and improves memory in aging mice
JC Newman, AJ Covarrubias, M Zhao, X Yu, P Gut, CP Ng, Y Huang, ...
Cell metabolism 26 (3), 547-557. e8, 2017
4092017
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
AJ Covarrubias, HI Aksoylar, J Yu, NW Snyder, AJ Worth, SS Iyer, J Wang, ...
elife 5, e11612, 2016
3612016
Control of macrophage metabolism and activation by mTOR and Akt signaling
AJ Covarrubias, HI Aksoylar, T Horng
Seminars in immunology 27 (4), 286-296, 2015
3482015
SARS-CoV-2, COVID-19 and the aging immune system
JM Bartleson, D Radenkovic, AJ Covarrubias, D Furman, DA Winer, ...
Nature aging 1 (9), 769-782, 2021
2602021
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ...
Nature metabolism 2 (11), 1265-1283, 2020
2372020
Toll-like receptor 3–mediated suppression of TRAMP prostate cancer shows the critical role of type I interferons in tumor immune surveillance
AI Chin, AK Miyahira, A Covarrubias, J Teague, B Guo, PW Dempsey, ...
Cancer research 70 (7), 2595-2603, 2010
1302010
ROS sets the stage for macrophage differentiation
A Covarrubias, V Byles, T Horng
Cell research 23 (8), 984-985, 2013
1072013
IL-6 strikes a balance in metabolic inflammation
AJ Covarrubias, T Horng
Cell metabolism 19 (6), 898-899, 2014
602014
Nuclear morphology is a deep learning biomarker of cellular senescence
I Heckenbach, GV Mkrtchyan, MB Ezra, D Bakula, JS Madsen, ...
Nature Aging 2 (8), 742-755, 2022
562022
The TSC-mTOR pathway regulates macrophage polarization. Nat Commun 4: 2834
V Byles, AJ Covarrubias, I Ben-Sahra, DW Lamming, DM Sabatini, ...
182013
The intestinal immune system and gut barrier function in obesity and ageing
SJ Shemtov, R Emani, O Bielska, AJ Covarrubias, E Verdin, JK Andersen, ...
The FEBS Journal 290 (17), 4163-4186, 2023
172023
Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ pro-inflammatory macrophages
AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ...
Biorxiv, 609438, 2019
132019
Aging-related inflammation driven by cellular senescence enhances NAD
AJ Covarrubias, JA Lopez-Dominguez, R Perrone
Trends Biochem Sci 32, 12-19, 2018
2018
THE ROLE OF MACROPHAGES IN NAD+ HOMEOSTASIS DURING AGING
AJ Covarrubias, EM Verdin
Innovation in Aging 1 (Suppl 1), 1205, 2017
2017
The Role of Nutrient Sensing in Macrophage Polarization
AJ Covarrubias
2016
SUPPRESSION OF PROSTATE CANCER GROWTH WITH ACTIVATION OF TOLL-LIKE RECEPTOR 3
AI Chin, A Miyahara, A Covarrubias, PW Dempsey, G Cheng
The Journal of Urology 181 (4S), 186-186, 2009
2009
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