Antioxidants accelerate lung cancer progression in mice VI Sayin, MX Ibrahim, E Larsson, JA Nilsson, P Lindahl, MO Bergo Science translational medicine 6 (221), 221ra15-221ra15, 2014 | 894 | 2014 |
Antioxidants can increase melanoma metastasis in mice K Le Gal, MX Ibrahim, C Wiel, VI Sayin, MK Akula, C Karlsson, MG Dalin, ... Science translational medicine 7 (308), 308re8-308re8, 2015 | 645 | 2015 |
BACH1 stabilization by antioxidants stimulates lung cancer metastasis C Wiel, K Le Gal, MX Ibrahim, CA Jahangir, M Kashif, H Yao, DV Ziegler, ... Cell 178 (2), 330-345. e22, 2019 | 404 | 2019 |
Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer M Liu, AKM Sjogren, C Karlsson, MX Ibrahim, KME Andersson, ... Proceedings of the National Academy of Sciences 107 (14), 6471-6476, 2010 | 140 | 2010 |
Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria MX Ibrahim, VI Sayin, MK Akula, M Liu, LG Fong, SG Young, MO Bergo Science 340 (6138), 1330-1333, 2013 | 130 | 2013 |
Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice OM Khan, MX Ibrahim, M Jonsson, C Karlsson, M Liu, AKM Sjogren, ... The Journal of clinical investigation 121 (2), 628-639, 2011 | 111 | 2011 |
Targeting filamin A reduces K-RAS–induced lung adenocarcinomas and endothelial response to tumor growth in mice RK Nallapalli, MX Ibrahim, AX Zhou, S Bandaru, SN Sunkara, B Redfors, ... Molecular cancer 11, 1-11, 2012 | 67 | 2012 |
Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions MK Akula, MX Ibrahim, EG Ivarsson, OM Khan, IT Kumar, M Erlandsson, ... Nature communications 10 (1), 3975, 2019 | 64 | 2019 |
Loss of one copy of Zfp148 reduces lesional macrophage proliferation and atherosclerosis in mice by activating p53 VI Sayin, OM Khan, LE Pehlivanoglu, A Staffas, MX Ibrahim, A Asplund, ... Circulation research 115 (9), 781-789, 2014 | 47 | 2014 |
A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells X Chen, H Yao, M Kashif, G Revêchon, M Eriksson, J Hu, T Wang, Y Liu, ... Elife 10, e63284, 2021 | 26 | 2021 |
Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment VI Sayin, A Nilton, MX Ibrahim, P Ågren, E Larsson, MM Petit, LM Hultén, ... PloS one 8 (2), e55720, 2013 | 24 | 2013 |
Mitochondria-targeted antioxidants MitoQ and MitoTEMPO do not influence BRAF-driven malignant melanoma and KRAS-driven lung cancer progression in mice K Le Gal, C Wiel, MX Ibrahim, M Henricsson, VI Sayin, MO Bergo Antioxidants 10 (2), 163, 2021 | 21 | 2021 |
Antioxidants promote intestinal tumor progression in mice ZV Zou, K Le Gal, AE El Zowalaty, LE Pehlivanoglu, V Garellick, N Gul, ... Antioxidants 10 (2), 241, 2021 | 18 | 2021 |
Antioxidants accelerate lung cancer progression in mice. Sci Transl Med. 2014; 6: 221ra15 VI Sayin, MX Ibrahim, E Larsson, JA Nilsson, P Lindahl, MO Bergo | 14 | |
Knockout of the RAS endoprotease RCE1 accelerates myeloid leukemia by downregulating GADD45b C Karlsson, MK Akula, A Staffas, J Cisowski, VI Sayin, MX Ibrahim, ... Leukemia 35 (2), 606-609, 2021 | 9 | 2021 |
Targeting RAS‐converting enzyme 1 overcomes senescence and improves progeria‐like phenotypes of ZMPSTE24 deficiency H Yao, X Chen, M Kashif, T Wang, MX Ibrahim, E Tüksammel, ... Aging cell 19 (8), e13200, 2020 | 8 | 2020 |
Antioxidants markedly accelerate tumor growth and reduce survival in mice with KRAS-and BRAF-induced lung cancer by disrupting the ROS-p53 axis VI Sayin, MX Ibrahim, E Larsson, JA Nilsson, P Lindahl, MO Bergö Cancer Research 74 (19_Supplement), 503-503, 2014 | 1 | 2014 |
Toward a New Therapy for Rapidly Aging Children MX Ibrahim, MO Bergo ACS Central Science 7 (8), 1292-1294, 2021 | | 2021 |
Hutchinson-Gilford Progeria Syndrome M Ibrahim | | 2014 |
Genetic Analyses of the CAAX Protein Prenyltransferases in Mice MX Ibrahim, OM Khan, MO Bergo The Enzymes 29, 259-274, 2011 | | 2011 |