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Prof Robin Franklin
Prof Robin Franklin
Professor of Stem Cell Medicine
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
VE Miron, A Boyd, JW Zhao, TJ Yuen, JM Ruckh, JL Shadrach, ...
Nature neuroscience 16 (9), 1211-1218, 2013
17072013
Remyelination in the CNS: from biology to therapy
RJM Franklin, C Ffrench-Constant
Nature Reviews Neuroscience 9 (11), 839-855, 2008
16662008
Single-cell RNA sequencing of microglia throughout the mouse lifespan and in the injured brain reveals complex cell-state changes
TR Hammond, C Dufort, L Dissing-Olesen, S Giera, A Young, A Wysoker, ...
Immunity 50 (1), 253-271. e6, 2019
15302019
Debris clearance by microglia: an essential link between degeneration and regeneration
H Neumann, MR Kotter, RJM Franklin
Brain 132 (2), 288-295, 2009
12122009
Why does remyelination fail in multiple sclerosis?
RJM Franklin
Nature Reviews Neuroscience 3 (9), 705-714, 2002
10072002
Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation
MR Kotter, WW Li, C Zhao, RJM Franklin
Journal of Neuroscience 26 (1), 328-332, 2006
8192006
Rejuvenation of regeneration in the aging central nervous system
JM Ruckh, JW Zhao, JL Shadrach, P van Wijngaarden, TN Rao, ...
Cell stem cell 10 (1), 96-103, 2012
7012012
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination
M Zawadzka, LE Rivers, SPJ Fancy, C Zhao, R Tripathi, F Jamen, ...
Cell stem cell 6 (6), 578-590, 2010
6622010
The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation
FJ Sim, C Zhao, J Penderis, RJM Franklin
Journal of Neuroscience 22 (7), 2451-2459, 2002
6572002
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
SPJ Fancy, SE Baranzini, C Zhao, DI Yuk, KA Irvine, S Kaing, N Sanai, ...
Genes & development 23 (13), 1571-1585, 2009
6522009
Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis
F Mei, SPJ Fancy, YAA Shen, J Niu, C Zhao, B Presley, E Miao, S Lee, ...
Nature medicine 20 (8), 954-960, 2014
5502014
Retinoid X receptor gamma signaling accelerates CNS remyelination
JK Huang, AA Jarjour, B Nait Oumesmar, C Kerninon, A Williams, ...
Nature neuroscience 14 (1), 45-53, 2011
5422011
Multiple sclerosis genetics
S Sawcer, RJM Franklin, M Ban
The Lancet Neurology 13 (7), 700-709, 2014
5292014
bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS
HA Arnett, SPJ Fancy, JA Alberta, C Zhao, SR Plant, S Kaing, CS Raine, ...
Science 306 (5704), 2111-2115, 2004
5132004
Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency
S Shen, J Sandoval, VA Swiss, J Li, J Dupree, RJM Franklin, ...
Nature neuroscience 11 (9), 1024-1034, 2008
5042008
Repair of demyelinated lesions by transplantation of purified 0-2A progenitor cells
AK Groves, SC Barnett, RJM Franklin, AJ Crang, M Mayer, WF Blakemore, ...
Nature 362 (6419), 453-455, 1993
5031993
Regenerating CNS myelin—from mechanisms to experimental medicines
RJM Franklin, C Ffrench-Constant
Nature Reviews Neuroscience 18 (12), 753-769, 2017
4802017
Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system
BG Brinkmann, A Agarwal, MW Sereda, AN Garratt, T Müller, H Wende, ...
Neuron 59 (4), 581-595, 2008
4682008
Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin‐induced demyelination
MR Kotter, A Setzu, FJ Sim, N Van Rooijen, RJM Franklin
Glia 35 (3), 204-212, 2001
4402001
Neuronal vulnerability and multilineage diversity in multiple sclerosis
L Schirmer, D Velmeshev, S Holmqvist, M Kaufmann, S Werneburg, ...
Nature 573 (7772), 75-82, 2019
4302019
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