| A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation H Zhao, R Ghirlando, C Alfonso, F Arisaka, I Attali, DL Bain, MM Bakhtina, ... PloS one 10 (5), e0126420, 2015 | 95 | 2015 |
| Effects of protein conformation, apparent solubility, and protein–protein interactions on the rates and mechanisms of aggregation for an IgG1Monoclonal antibody C Kalonia, V Toprani, R Toth, N Wahome, I Gabel, CR Middaugh, ... The Journal of Physical Chemistry B 120 (29), 7062-7075, 2016 | 60 | 2016 |
| N-Terminus of IpaB Provides a Potential Anchor to the Shigella Type III Secretion System Tip Complex Protein IpaD NE Dickenson, O Arizmendi, MK Patil, RT Toth IV, CR Middaugh, ... Biochemistry 52 (49), 8790-8799, 2013 | 42 | 2013 |
| High-definition mapping of four spatially distinct neutralizing epitope clusters on RiVax, a candidate ricin toxin subunit vaccine RT Toth IV, SK Angalakurthi, G Van Slyke, DJ Vance, JM Hickey, SB Joshi, ... Clinical and Vaccine Immunology 24 (12), e00237-17, 2017 | 41 | 2017 |
| Spa47 is an oligomerization‐activated type three secretion system (T3SS) ATPase from Shigella flexneri JL Burgess, HB Jones, P Kumar, RT Toth IV, CR Middaugh, E Antony, ... Protein Science 25 (5), 1037-1048, 2016 | 35 | 2016 |
| Evaluation of hydrogen exchange mass spectrometry as a stability-indicating method for formulation excipient screening for an IgG4 monoclonal antibody RT Toth IV, SE Pace, BJ Mills, SB Joshi, R Esfandiary, CR Middaugh, ... Journal of Pharmaceutical Sciences 107 (4), 1009-1019, 2018 | 28 | 2018 |
| Impact of detergent on biophysical properties and immune response of the IpaDB fusion protein, a candidate subunit vaccine against Shigella species X Chen, SP Choudhari, FJ Martinez-Becerra, JH Kim, NE Dickenson, ... Infection and immunity 83 (1), 292-299, 2015 | 25 | 2015 |
| Impact of glycosylation on the local backbone flexibility of well-defined IgG1-Fc glycoforms using hydrogen exchange-mass spectrometry AS More, RT Toth IV, SZ Okbazghi, CR Middaugh, SB Joshi, TJ Tolbert, ... Journal of pharmaceutical sciences 107 (9), 2315-2324, 2018 | 21 | 2018 |
| Recombinant subunit rotavirus trivalent vaccine candidate: physicochemical comparisons and stability evaluations of three protein antigens S Agarwal, JM Hickey, N Sahni, RT Toth IV, GA Robertson, R Sitrin, ... Journal of pharmaceutical sciences 109 (1), 380-393, 2020 | 19 | 2020 |
| Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies A Bazzoli, DJ Vance, MJ Rudolph, Y Rong, SK Angalakurthi, RT Toth IV, ... Proteins: Structure, Function, and Bioinformatics 85 (11), 1994-2008, 2017 | 19 | 2017 |
| Empirical correction for differences in chemical exchange rates in hydrogen exchange-mass spectrometry measurements RT Toth IV, BJ Mills, SB Joshi, R Esfandiary, SM Bishop, CR Middaugh, ... Analytical chemistry 89 (17), 8931-8941, 2017 | 16 | 2017 |
| Fine-specificity epitope analysis identifies contact points on ricin toxin recognized by protective monoclonal antibodies G Van Slyke, SK Angalakurthi, RT Toth, DJ Vance, Y Rong, D Ehrbar, ... Immunohorizons 2 (8), 262-273, 2018 | 13 | 2018 |
| Structural characterization and physicochemical stability profile of a double mutant heat labile toxin protein based adjuvant VM Toprani, JM Hickey, N Sahni, RT Toth IV, GA Robertson, ... Journal of Pharmaceutical Sciences 106 (12), 3474-3485, 2017 | 9 | 2017 |
| Challenges and opportunities of using liquid chromatography and mass spectrometry methods to develop complex vaccine antigens as pharmaceutical dosage forms JM Hickey, N Sahni, RT Toth IV, OS Kumru, SB Joshi, CR Middaugh, ... Journal of Chromatography B 1032, 23-38, 2016 | 9 | 2016 |
| Biophysical characterization of the type III secretion system translocator proteins and the translocator proteins attached to bacterium-like particles X Chen, SP Choudhari, P Kumar, RT Toth IV, JH Kim, ML Van Roosmalen, ... Journal of Pharmaceutical Sciences 104 (12), 4065-4073, 2015 | 9 | 2015 |
| Oligomeric states and hydrodynamic properties of lysyl oxidase-like 2 AA Meier, HJ Moon, R Toth IV, E Folta-Stogniew, K Kuczera, ... Biomolecules 11 (12), 1846, 2021 | 7 | 2021 |
| Characterization of excipient effects on reversible self-association, backbone flexibility, and solution properties of an IgG1 monoclonal antibody at high concentrations: part 2 Y Hu, RT Toth IV, SB Joshi, R Esfandiary, CR Middaugh, DB Volkin, ... Journal of Pharmaceutical Sciences 109 (1), 353-363, 2020 | 7 | 2020 |
| Site-specific hydrolysis reaction C-terminal of methionine in Met-His during metal-catalyzed oxidation of IgG-1 O Mozziconacci, J Arora, RT Toth IV, SB Joshi, S Zhou, DB Volkin, ... Molecular Pharmaceutics 13 (4), 1317-1328, 2016 | 7 | 2016 |
| Fine Specificity Epitope Analysis by HX-MS Identifies Contact Points on Ricin Toxin Recognized by Protective Monoclonal Antibodies GV Slyke, SK Angalakurthi, RT Toth IV, DJ Vance, Y Rong, D Ehrbar, ... bioRxiv, 345561, 2018 | | 2018 |
| Spa47 is an oligomerization-activated type three secretion system (T3SS) ATPase fromShigella flexneri JL Burgess, HB Jones, P Kumar, RT Toth IV, CR Middaugh, E Antony, ... | | 2016 |
