The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy VS Burchell, DE Nelson, A Sanchez-Martinez, M Delgado-Camprubi, ... Nature neuroscience 16 (9), 1257-1265, 2013 | 356 | 2013 |
The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease DC Schöndorf, D Ivanyuk, P Baden, A Sanchez-Martinez, S De Cicco, ... Cell reports 23 (10), 2976-2988, 2018 | 300 | 2018 |
Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin JJ Lee, A Sanchez-Martinez, AM Zarate, C Benincá, U Mayor, MJ Clague, ... Journal of Cell Biology 217 (5), 1613-1622, 2018 | 282 | 2018 |
Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models A Sanchez-Martinez, M Beavan, ME Gegg, KY Chau, AJ Whitworth, ... Scientific reports 6 (1), 1-12, 2016 | 162 | 2016 |
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits GM Hautbergue, LM Castelli, L Ferraiuolo, A Sanchez-Martinez, ... Nature communications 8 (1), 1-18, 2017 | 136 | 2017 |
Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy RM Ivatt, A Sanchez-Martinez, VK Godena, S Brown, E Ziviani, ... Proceedings of the National Academy of Sciences 111 (23), 8494-8499, 2014 | 132 | 2014 |
Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration A Loreto, CS Hill, VL Hewitt, G Orsomando, C Angeletti, J Gilley, C Lucci, ... Neurobiology of disease 134, 104678, 2020 | 108 | 2020 |
The complex I subunit NDUFA10 selectively rescues Drosophila pink1 mutants through a mechanism independent of mitophagy JH Pogson, RM Ivatt, A Sanchez-Martinez, R Tufi, E Wilson, H Mortiboys, ... PLoS Genet 10 (11), e1004815, 2014 | 78 | 2014 |
Superoxide dismutase (SOD)-mimetic M40403 is protective in cell and fly models of paraquat toxicity: implications for Parkinson disease R Filograna, VK Godena, A Sanchez-Martinez, E Ferrari, L Casella, ... Journal of Biological Chemistry 291 (17), 9257-9267, 2016 | 75 | 2016 |
Comprehensive genetic characterization of mitochondrial Ca2+ uniporter components reveals their different physiological requirements in vivo R Tufi, TP Gleeson, S von Stockum, VL Hewitt, JJ Lee, A Terriente-Felix, ... Cell reports 27 (5), 1541-1550. e5, 2019 | 55 | 2019 |
Modeling human mitochondrial diseases in flies Á Sánchez-Martínez, N Luo, P Clemente, C Adán, R Hernández-Sierra, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1757 (9-10), 1190-1198, 2006 | 37 | 2006 |
Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss A Biosa, A Sanchez-Martinez, R Filograna, A Terriente-Felix, SM Alam, ... Human molecular genetics 27 (9), 1618-1629, 2018 | 31 | 2018 |
Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila S Andreazza, CL Samstag, A Sanchez-Martinez, E Fernandez-Vizarra, ... Nature communications 10 (1), 1-14, 2019 | 30 | 2019 |
Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction S Von Stockum, A Sanchez-Martinez, S Corrà, J Chakraborty, ... Life science alliance 2 (2), 2019 | 30 | 2019 |
Coiled coil domain-containing protein 56 (CCDC56) is a novel mitochondrial protein essential for cytochrome c oxidase function S Peralta, P Clemente, Á Sánchez-Martínez, M Calleja, ... Journal of Biological Chemistry 287 (29), 24174-24185, 2012 | 27 | 2012 |
Modeling pathogenic mutations of human twinkle in Drosophila suggests an apoptosis role in response to mitochondrial defects A Sanchez-Martinez, M Calleja, S Peralta, Y Matsushima, ... PLoS One 7 (8), e43954, 2012 | 25 | 2012 |
Characterization of Drosophila ATPsynC mutants as a new model of mitochondrial ATP synthase disorders D Lovero, L Giordano, RM Marsano, A Sanchez-Martinez, H Boukhatmi, ... Plos one 13 (8), e0201811, 2018 | 10 | 2018 |
SRSF1-dependent nuclear export of C9ORF72 repeat transcripts: targeting toxic gain-of-functions induced by protein sequestration as a selective therapeutic strategy for … LM Castelli, YH Lin, L Ferraiuolo, A Sanchez-Martinez, K Ning, M Azzouz, ... Therapeutic Targets for Neurological Diseases 4, 2017 | 4 | 2017 |
A comprehensive genetic characterisation of the mitochondrial Ca2+ uniporter in Drosophila R Tufi, TP Gleeson, S Von Stockum, VL Hewitt, JJ Lee, A Terriente-Felix, ... BioRxiv, 458174, 2018 | 2 | 2018 |
Intergenomic nuclear-mitochondrial cross-talk in Drosophila melanogaster L Echevarría, Á Sánchez-Martínez, P Clemente, R Hernández-Sierra, ... Landes Bioscience, 2010 | 2 | 2010 |