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Alvaro Sanchez-Martinez
Alvaro Sanchez-Martinez
Investigator Scientist, University of Cambridge
Email verificata su mrc-mbu.cam.ac.uk
Titolo
Citata da
Citata da
Anno
The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy
VS Burchell, DE Nelson, A Sanchez-Martinez, M Delgado-Camprubi, ...
Nature neuroscience 16 (9), 1257-1265, 2013
3562013
The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease
DC Schöndorf, D Ivanyuk, P Baden, A Sanchez-Martinez, S De Cicco, ...
Cell reports 23 (10), 2976-2988, 2018
3002018
Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin
JJ Lee, A Sanchez-Martinez, AM Zarate, C Benincá, U Mayor, MJ Clague, ...
Journal of Cell Biology 217 (5), 1613-1622, 2018
2822018
Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models
A Sanchez-Martinez, M Beavan, ME Gegg, KY Chau, AJ Whitworth, ...
Scientific reports 6 (1), 1-12, 2016
1622016
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits
GM Hautbergue, LM Castelli, L Ferraiuolo, A Sanchez-Martinez, ...
Nature communications 8 (1), 1-18, 2017
1362017
Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy
RM Ivatt, A Sanchez-Martinez, VK Godena, S Brown, E Ziviani, ...
Proceedings of the National Academy of Sciences 111 (23), 8494-8499, 2014
1322014
Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration
A Loreto, CS Hill, VL Hewitt, G Orsomando, C Angeletti, J Gilley, C Lucci, ...
Neurobiology of disease 134, 104678, 2020
1082020
The complex I subunit NDUFA10 selectively rescues Drosophila pink1 mutants through a mechanism independent of mitophagy
JH Pogson, RM Ivatt, A Sanchez-Martinez, R Tufi, E Wilson, H Mortiboys, ...
PLoS Genet 10 (11), e1004815, 2014
782014
Superoxide dismutase (SOD)-mimetic M40403 is protective in cell and fly models of paraquat toxicity: implications for Parkinson disease
R Filograna, VK Godena, A Sanchez-Martinez, E Ferrari, L Casella, ...
Journal of Biological Chemistry 291 (17), 9257-9267, 2016
752016
Comprehensive genetic characterization of mitochondrial Ca2+ uniporter components reveals their different physiological requirements in vivo
R Tufi, TP Gleeson, S von Stockum, VL Hewitt, JJ Lee, A Terriente-Felix, ...
Cell reports 27 (5), 1541-1550. e5, 2019
552019
Modeling human mitochondrial diseases in flies
Á Sánchez-Martínez, N Luo, P Clemente, C Adán, R Hernández-Sierra, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1757 (9-10), 1190-1198, 2006
372006
Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss
A Biosa, A Sanchez-Martinez, R Filograna, A Terriente-Felix, SM Alam, ...
Human molecular genetics 27 (9), 1618-1629, 2018
312018
Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila
S Andreazza, CL Samstag, A Sanchez-Martinez, E Fernandez-Vizarra, ...
Nature communications 10 (1), 1-14, 2019
302019
Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction
S Von Stockum, A Sanchez-Martinez, S Corrà, J Chakraborty, ...
Life science alliance 2 (2), 2019
302019
Coiled coil domain-containing protein 56 (CCDC56) is a novel mitochondrial protein essential for cytochrome c oxidase function
S Peralta, P Clemente, Á Sánchez-Martínez, M Calleja, ...
Journal of Biological Chemistry 287 (29), 24174-24185, 2012
272012
Modeling pathogenic mutations of human twinkle in Drosophila suggests an apoptosis role in response to mitochondrial defects
A Sanchez-Martinez, M Calleja, S Peralta, Y Matsushima, ...
PLoS One 7 (8), e43954, 2012
252012
Characterization of Drosophila ATPsynC mutants as a new model of mitochondrial ATP synthase disorders
D Lovero, L Giordano, RM Marsano, A Sanchez-Martinez, H Boukhatmi, ...
Plos one 13 (8), e0201811, 2018
102018
SRSF1-dependent nuclear export of C9ORF72 repeat transcripts: targeting toxic gain-of-functions induced by protein sequestration as a selective therapeutic strategy for …
LM Castelli, YH Lin, L Ferraiuolo, A Sanchez-Martinez, K Ning, M Azzouz, ...
Therapeutic Targets for Neurological Diseases 4, 2017
42017
A comprehensive genetic characterisation of the mitochondrial Ca2+ uniporter in Drosophila
R Tufi, TP Gleeson, S Von Stockum, VL Hewitt, JJ Lee, A Terriente-Felix, ...
BioRxiv, 458174, 2018
22018
Intergenomic nuclear-mitochondrial cross-talk in Drosophila melanogaster
L Echevarría, Á Sánchez-Martínez, P Clemente, R Hernández-Sierra, ...
Landes Bioscience, 2010
22010
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20