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Chancievan Thangaratnarajah
Chancievan Thangaratnarajah
Senior Scientist (Cryo-EM) at Nxera Pharma
Keine bestätigte E-Mail-Adresse - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases
P Canning, CDO Cooper, T Krojer, JW Murray, ACW Pike, A Chaikuad, ...
Journal of Biological Chemistry 288 (11), 7803-7814, 2013
2932013
The SLC25 carrier family: important transport proteins in mitochondrial physiology and pathology
ERS Kunji, MS King, JJ Ruprecht, C Thangaratnarajah
Physiology 35 (5), 302-327, 2020
942020
Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers
C Thangaratnarajah, JJ Ruprecht, ERS Kunji
Nature communications 5 (1), 5491, 2014
872014
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds
S Rempel, C Gati, M Nijland, C Thangaratnarajah, A Karyolaimos, ...
Nature 580 (7803), 409-412, 2020
862020
Trends in thermostability provide information on the nature of substrate, inhibitor, and lipid interactions with mitochondrial carriers
PG Crichton, Y Lee, JJ Ruprecht, E Cerson, C Thangaratnarajah, MS King, ...
Journal of Biological Chemistry 290 (13), 8206-8217, 2015
722015
The mitochondrial dicarboxylate and 2-oxoglutarate carriers do not transport glutathione
LM Booty, MS King, C Thangaratnarajah, H Majd, AM James, ERS Kunji, ...
FEBS letters 589 (5), 621-628, 2015
722015
The yeast mitochondrial pyruvate carrier is a hetero‐dimer in its functional state
S Tavoulari, C Thangaratnarajah, V Mavridou, ME Harbour, JC Martinou, ...
The EMBO journal 38 (10), e100785, 2019
562019
Bacterial multi‐solute transporters
DJ Slotboom, TW Ettema, M Nijland, C Thangaratnarajah
FEBS letters 594 (23), 3898-3907, 2020
172020
Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency
S Tavoulari, D Lacabanne, C Thangaratnarajah, ERS Kunji
Trends in Endocrinology & Metabolism 33 (8), 539-553, 2022
142022
Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension
A Chaikuad, C Thangaratnarajah, F von Delft, AN Bullock
Scientific reports 9 (1), 18351, 2019
132019
Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM
C Thangaratnarajah, J Rheinberger, C Paulino, DJ Slotboom
Proceedings of the National Academy of Sciences 118 (34), e2105014118, 2021
122021
Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer
S Tavoulari, TJJ Schirris, V Mavridou, C Thangaratnarajah, MS King, ...
Molecular metabolism 60, 101469, 2022
102022
Membrane transport of cobalamin
M Nijland, JMM Felices, DJ Slotboom, C Thangaratnarajah
Vitamins and Hormones 119, 121-148, 2022
82022
Expulsion mechanism of the substrate-translocating subunit in ECF transporters
C Thangaratnarajah, M Nijland, L Borges-Araújo, A Jeucken, ...
Nature Communications 14 (1), 4484, 2023
42023
Cryo-EM studies of membrane proteins at 200 keV
C Thangaratnarajah, J Rheinberger, C Paulino
Current Opinion in Structural Biology 76, 102440, 2022
42022
Bidirectional ATP-driven transport of cobalamin by the mycobacterial ABC transporter BacA
M Nijland, SN Lefebvre, C Thangaratnarajah, DJ Slotboom
Nature Communications 15 (1), 2626, 2024
2024
The structural and functional characterisation of the mitochondrial aspartate-glutamate carriers
C Thangaratnarajah
University of Cambridge, 2015
2015
Structural basis for Cul3 protein assembly
OG Marsden, S Knapp, F Hojzan, V Ayinampudi, D Brian, ...
THE JOURNAL OF BIOLOGICAL CHEMISTRY 288 (39), 28304, 2013
2013
The functional and structural analysis of the mitochondrial aspartate–glutamate carrier
C Thangaratnarajah, ERS Kunji
Biochimica et Biophysica Acta 187 (Supplement), S37-S38, 2012
2012
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