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AG Loxton
AG Loxton
Medical Scientist
Verified email at sun.ac.za
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Year
A blood RNA signature for tuberculosis disease risk: a prospective cohort study
DE Zak, A Penn-Nicholson, TJ Scriba, E Thompson, S Suliman, LM Amon, ...
The Lancet 387 (10035), 2312-2322, 2016
7462016
Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure
ST Malherbe, S Shenai, K Ronacher, AG Loxton, G Dolganov, M Kriel, ...
Nature medicine 22 (10), 1094-1100, 2016
2762016
Four-gene pan-African blood signature predicts progression to tuberculosis
S Suliman, EG Thompson, J Sutherland, J Weiner 3rd, MOC Ota, ...
American journal of respiratory and critical care medicine 197 (9), 1198-1208, 2018
2562018
Immunogenicity of Novel DosR Regulon-Encoded Candidate Antigens of Mycobacterium tuberculosis in Three High-Burden Populations in Africa
GF Black, BA Thiel, MO Ota, SK Parida, R Adegbola, WH Boom, ...
Clinical and Vaccine Immunology 16 (8), 1203-1212, 2009
1862009
Increased Frequency of Myeloid-derived Suppressor Cells during Active Tuberculosis and after Recent Mycobacterium tuberculosis Infection Suppresses T-Cell …
N Du Plessis, L Loebenberg, M Kriel, F von Groote-Bidlingmaier, ...
American journal of respiratory and critical care medicine 188 (6), 724-732, 2013
1782013
Host blood RNA signatures predict the outcome of tuberculosis treatment
EG Thompson, Y Du, ST Malherbe, S Shankar, J Braun, J Valvo, ...
Tuberculosis 107, 48-58, 2017
1672017
Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and …
NN Chegou, JS Sutherland, S Malherbe, AC Crampin, PLAM Corstjens, ...
Thorax 71 (9), 785-794, 2016
1672016
Safety and immunogenicity of the recombinant Mycobacterium bovis BCG vaccine VPM1002 in HIV-unexposed newborn infants in South Africa
AG Loxton, JK Knaul, L Grode, A Gutschmidt, C Meller, B Eisele, ...
Clinical and Vaccine Immunology 24 (2), e00439-16, 2017
1442017
Optimization and Interpretation of Serial QuantiFERON Testing to Measure Acquisition of Mycobacterium tuberculosis Infection
E Nemes, V Rozot, H Geldenhuys, N Bilek, S Mabwe, D Abrahams, ...
American journal of respiratory and critical care medicine 196 (5), 638-648, 2017
1402017
Metabolite changes in blood predict the onset of tuberculosis
J Weiner 3rd, J Maertzdorf, JS Sutherland, FJ Duffy, E Thompson, ...
Nature communications 9 (1), 5208, 2018
1352018
Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial
TJ Scriba, A Fiore-Gartland, A Penn-Nicholson, H Mulenga, SK Mbandi, ...
The Lancet Infectious Diseases 21 (3), 354-365, 2021
1062021
Identification of novel host biomarkers in plasma as candidates for the immunodiagnosis of tuberculosis disease and monitoring of tuberculosis treatment response
R Jacobs, S Malherbe, AG Loxton, K Stanley, G Van Der Spuy, G Walzl, ...
Oncotarget 7 (36), 57581, 2016
1002016
Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting
NN Chegou, GF Black, AG Loxton, K Stanley, PN Essone, MR Klein, ...
BMC infectious diseases 12, 1-14, 2012
992012
B cells producing type I IFN modulate macrophage polarization in tuberculosis
A Bénard, I Sakwa, P Schierloh, A Colom, I Mercier, L Tailleux, L Jouneau, ...
American journal of respiratory and critical care medicine 197 (6), 801-813, 2018
852018
Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity
JS Sutherland, AG Loxton, MC Haks, D Kassa, L Ambrose, JS Lee, L Ran, ...
Clinical microbiology and infection 20 (4), O230-O238, 2014
852014
Host biomarkers detected in saliva show promise as markers for the diagnosis of pulmonary tuberculosis disease and monitoring of the response to tuberculosis treatment
R Jacobs, E Tshehla, S Malherbe, M Kriel, AG Loxton, K Stanley, ...
Cytokine 81, 50-56, 2016
752016
Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area
NN Chegou, PN Essone, AG Loxton, K Stanley, GF Black, ...
PloS one 7 (6), e38501, 2012
742012
Differential expression of host biomarkers in saliva and serum samples from individuals with suspected pulmonary tuberculosis
KG Phalane, M Kriel, AG Loxton, A Menezes, K Stanley, GD Van der Spuy, ...
Mediators of inflammation 2013, 2013
712013
Serologic diagnosis of tuberculosis by combining Ig classes against selected mycobacterial targets
R Baumann, S Kaempfer, NN Chegou, W Oehlmann, AG Loxton, ...
Journal of Infection 69 (6), 581-589, 2014
692014
Epigenetics and proteomics join transcriptomics in the quest for tuberculosis biomarkers
MM Esterhuyse, J Weiner 3rd, E Caron, AG Loxton, M Iannaccone, ...
MBio 6 (5), 10.1128/mbio. 01187-15, 2015
682015
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