| Programmable RNA recognition and cleavage by CRISPR/Cas9 MR O’Connell, BL Oakes, SH Sternberg, A East-Seletsky, M Kaplan, ... Nature 516 (7530), 263-266, 2014 | 739 | 2014 |
| CasX enzymes comprise a distinct family of RNA-guided genome editors JJ Liu, N Orlova, BL Oakes, E Ma, HB Spinner, KLM Baney, J Chuck, ... Nature 566 (7743), 218-223, 2019 | 409 | 2019 |
| Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors TP Huang, KT Zhao, SM Miller, NM Gaudelli, BL Oakes, C Fellmann, ... Nature biotechnology 37 (6), 626-631, 2019 | 245 | 2019 |
| Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch BL Oakes, DC Nadler, A Flamholz, C Fellmann, BT Staahl, JA Doudna, ... Nature biotechnology 34 (6), 646-651, 2016 | 208 | 2016 |
| Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast RS McIsaac, BL Oakes, X Wang, KA Dummit, D Botstein, MB Noyes Nucleic acids research 41 (4), e57-e57, 2013 | 171 | 2013 |
| Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs K Kundert, JE Lucas, KE Watters, C Fellmann, AH Ng, BM Heineike, ... Nature communications 10 (1), 2127, 2019 | 166 | 2019 |
| A systematic survey of the Cys2His2 zinc finger DNA-binding landscape AV Persikov, JL Wetzel, EF Rowland, BL Oakes, DJ Xu, M Singh, ... Nucleic acids research 43 (3), 1965-1984, 2015 | 115 | 2015 |
| CRISPR-Cas9 circular permutants as programmable scaffolds for genome modification BL Oakes, C Fellmann, H Rishi, KL Taylor, SM Ren, DC Nadler, R Yokoo, ... Cell 176 (1), 254-267. e16, 2019 | 105 | 2019 |
| Real-time optogenetic control of intracellular protein concentration in microbial cell cultures J Melendez, M Patel, BL Oakes, P Xu, P Morton, MN McClean Integrative Biology 6 (3), 366-372, 2014 | 77 | 2014 |
| A yeast optogenetic toolkit (yOTK) for gene expression control in Saccharomyces cerevisiae J An‐adirekkun, CJ Stewart, SH Geller, MT Patel, J Melendez, BL Oakes, ... Biotechnology and bioengineering 117 (3), 886-893, 2020 | 43 | 2020 |
| Deep sequencing of large library selections allows computational discovery of diverse sets of zinc fingers that bind common targets AV Persikov, EF Rowland, BL Oakes, M Singh, MB Noyes Nucleic acids research 42 (3), 1497-1508, 2014 | 41 | 2014 |
| Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules A Shams, SA Higgins, C Fellmann, TG Laughlin, BL Oakes, R Lew, S Kim, ... Nature Communications 12 (1), 5664, 2021 | 37 | 2021 |
| Protein Engineering of Cas9 for Enhanced Function. BL Oakes, DC Nadler, DF Savage Methods in enzymology 546, 491-511, 2014 | 34 | 2014 |
| Copper modulates the phenotypic response of activated BV2 microglia through the release of nitric oxide A Rossi-George, CJ Guo, BL Oakes, AJ Gow Nitric Oxide 27 (4), 201-209, 2012 | 30 | 2012 |
| Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing BL Oakes, DF Xia, EF Rowland, DJ Xu, I Ankoudinova, JS Borchardt, ... Nature Communications 7 (1), 10194, 2016 | 23 | 2016 |
| Methods and compositions for modifying a single stranded target nucleic acid JA Doudna, SH Sternberg, M O'connell, B Oakes US Patent 9,994,831, 2018 | 18 | 2018 |
| Rapid synthesis and screening of chemically activated transcription factors with GFP-based reporters RS McIsaac, BL Oakes, D Botstein, MB Noyes JoVE (Journal of Visualized Experiments), e51153-e51153, 2013 | 10 | 2013 |
| New approaches for targeting PCSK9: small-interfering ribonucleic acid and genome editing RF Oostveen, AV Khera, S Kathiresan, ESG Stroes, K Fitzgerald, ... Arteriosclerosis, thrombosis, and vascular biology 43 (7), 1081-1092, 2023 | 9 | 2023 |
| CRISPR-CasX is an RNA-dominated enzyme active for human genome editing JJ Liu, N Orlova, BL Oakes, E Ma, HB Spinner, KLM Baney, J Chuck, ... Nature 566 (7743), 218, 2019 | 9 | 2019 |
| Methods and compositions for modifying a single stranded target nucleic acid JA Doudna, SH Sternberg, M O'connell, B Oakes US Patent 10,494,620, 2019 | 3 | 2019 |
Jennifer DoudnaProfessor of Molecular and Cell Biology and Chemistry, UC BerkeleyVerified email at berkeley.edu
