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Srijit Seal
Srijit Seal
Broad Institute of MIT and Harvard, University of Cambridge
Verified email at broad.mit.edu - Homepage
Title
Cited by
Cited by
Year
Integrating cell morphology with gene expression and chemical structure to aid mitochondrial toxicity detection
S Seal, J Carreras-Puigvert, MA Trapotsi, H Yang, O Spjuth, A Bender
Communications Biology 5 (858), 2022
39*2022
Comparison of cellular morphological descriptors and molecular fingerprints for the prediction of cytotoxicity-and proliferation-related assays
S Seal, H Yang, L Vollmers, A Bender
Chemical Research in Toxicology 34 (2), 422-437, 2021
292021
Using chemical and biological data to predict drug toxicity
A Liu, S Seal, H Yang, A Bender
SLAS Discovery 28 (3), 53-64, 2023
182023
Merging bioactivity predictions from cell morphology and chemical fingerprint models using similarity to training data
S Seal, H Yang, MA Trapotsi, S Singh, J Carreras-Puigvert, O Spjuth, ...
Journal of Cheminformatics 15 (1), 56, 2023
152023
From pixels to phenotypes: Integrating image-based profiling with cell health data as BioMorph features improves interpretability
S Seal, J Carreras-Puigvert, S Singh, AE Carpenter, O Spjuth, A Bender
Molecular Biology of the Cell 35 (3), mr2, 2024
52024
Using Generative Modeling to Endow with Potency Initially Inert Compounds with Good Bioavailability and Low Toxicity
RI Horne, J Wilson-Godber, A González Díaz, ZF Brotzakis, S Seal, ...
Journal of Chemical Information and Modeling, 2024
52024
Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA Drug-Induced Cardiotoxicity Rank
S Seal, O Spjuth, L Hosseini-Gerami, M García-Ortegón, S Singh, ...
Journal of Chemical Information and Modeling, 2024
3*2024
Improved Early Detection of Drug-Induced Liver Injury by Integrating Predicted in Vivo and in Vitro Data
S Seal, DP Williams, L Hosseini-Gerami, O Spjuth, A Bender
bioRxiv, 2024.01. 10.575128, 2024
22024
Understanding Biology in the Age of Artificial Intelligence
E Lawrence, A El-Shazly, S Seal, CK Joshi, P Liò, S Singh, A Bender, ...
arXiv preprint arXiv:2403.04106, 2024
2024
Calibrated prediction of scarce adverse drug reaction labels with conditional neural processes
M Garcia Ortegon, S Seal, S Singh, A Bender, S Bacallado
ICLR 2024 DMLR Workshop, 2024
2024
PKSmart: An Open-Source Computational Model to Predict in vivo Pharmacokinetics of Small Molecules
S Seal, M Trapotsi, V Subramanian, O Spjuth, N Greene, A Bender
bioRxiv, 2024.02. 02.578658, 2024
2024
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Articles 1–11