| NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis JD Brown, CY Lin, Q Duan, G Griffin, AJ Federation, RM Paranal, S Bair, ... Molecular cell 56 (2), 219-231, 2014 | 595 | 2014 |
| RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity E Pefanis, J Wang, G Rothschild, J Lim, D Kazadi, J Sun, A Federation, ... Cell 161 (4), 774-789, 2015 | 447 | 2015 |
| Active medulloblastoma enhancers reveal subgroup-specific cellular origins CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ... Nature 530 (7588), 57-62, 2016 | 393 | 2016 |
| Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors W Yu, EJ Chory, AK Wernimont, W Tempel, A Scopton, A Federation, ... Nature communications 3 (1), 1288, 2012 | 296 | 2012 |
| Models of human core transcriptional regulatory circuitries V Saint-André, AJ Federation, CY Lin, BJ Abraham, J Reddy, TI Lee, ... Genome research 26 (3), 385-396, 2016 | 273 | 2016 |
| MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism P Bandopadhayay, LA Ramkissoon, P Jain, G Bergthold, J Wala, R Zeid, ... Nature genetics 48 (3), 273-282, 2016 | 269 | 2016 |
| Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability FL Meng, Z Du, A Federation, J Hu, Q Wang, KR Kieffer-Kwon, ... Cell 159 (7), 1538-1548, 2014 | 260 | 2014 |
| Tuning β-sheet peptide self-assembly and hydrogelation behavior by modification of sequence hydrophobicity and aromaticity CJ Bowerman, W Liyanage, AJ Federation, BL Nilsson Biomacromolecules 12 (7), 2735-2745, 2011 | 201 | 2011 |
| Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101-105, 2018 | 195 | 2018 |
| Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung cancer H Zhang, J Qi, JM Reyes, L Li, PK Rao, F Li, CY Lin, JA Perry, MA Lawlor, ... Cancer discovery 6 (9), 1006-1021, 2016 | 122 | 2016 |
| Enhancer architecture and essential core regulatory circuitry of chronic lymphocytic leukemia CJ Ott, AJ Federation, LS Schwartz, S Kasar, JL Klitgaard, R Lenci, Q Li, ... Cancer cell 34 (6), 982-995. e7, 2018 | 116 | 2018 |
| Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis J Cheng, DE Park, C Berrios, EA White, R Arora, R Yoon, T Branigan, ... PLoS pathogens 13 (10), e1006668, 2017 | 111 | 2017 |
| The use of small molecules in somatic-cell reprogramming AJ Federation, JE Bradner, A Meissner Trends in cell biology 24 (3), 179-187, 2014 | 87 | 2014 |
| BET bromodomain proteins regulate enhancer function during adipogenesis JD Brown, ZB Feldman, SP Doherty, JM Reyes, PB Rahl, CY Lin, ... Proceedings of the National Academy of Sciences 115 (9), 2144-2149, 2018 | 75 | 2018 |
| Targeting nuclear receptor NR4A1–dependent adipocyte progenitor quiescence promotes metabolic adaptation to obesity Y Zhang, AJ Federation, S Kim, JP O’Keefe, M Lun, D Xiang, JD Brown, ... The Journal of Clinical Investigation 128 (11), 4898-4911, 2018 | 24 | 2018 |
| Highly parallel quantification and compartment localization of transcription factors and nuclear proteins AJ Federation, V Nandakumar, BC Searle, A Stergachis, H Wang, LK Pino, ... Cell Reports 30 (8), 2463-2471. e5, 2020 | 22 | 2020 |
| Structure-guided DOT1L probe optimization by label-free ligand displacement JS Yi, AJ Federation, J Qi, S Dhe-Paganon, M Hadler, X Xu, R St. Pierre, ... ACS chemical biology 10 (3), 667-674, 2015 | 22 | 2015 |
| Mutual balance of histone deacetylases 1 and 2 and the acetyl reader ATAD2 regulates the level of acetylation of histone H4 on nascent chromatin of human cells P Lazarchuk, J Hernandez-Villanueva, MN Pavlova, A Federation, ... Molecular and Cellular Biology 40 (9), e00421-19, 2020 | 21 | 2020 |
| Identification of candidate master transcription factors within enhancer-centric transcriptional regulatory networks AJ Federation, DR Polaski, CJ Ott, A Fan, CY Lin, JE Bradner BioRxiv, 345413, 2018 | 10 | 2018 |
| Building spectral libraries from narrow-window data-independent acquisition mass spectrometry data LR Heil, WE Fondrie, CD McGann, AJ Federation, WS Noble, ... Journal of proteome research 21 (6), 1382-1391, 2022 | 8 | 2022 |
