Cell engineering and cultivation of Chinese hamster ovary (CHO) cells T Omasa, M Onitsuka, WD Kim Current pharmaceutical biotechnology 11 (3), 233-240, 2010 | 227 | 2010 |
Effects of lactate concentration on hybridoma culture in lactate‐controlled fed‐batch operation T Omasa, KI Higashiyama, S Shioya, K Suga Biotechnology and bioengineering 39 (5), 556-564, 1992 | 182 | 1992 |
Effect of methanol concentration on the production of human β2-glycoprotein I domain V by a recombinant Pichia pastoris: a simple system for the control of methanol … Y Katakura, W Zhang, G Zhuang, T Omasa, M Kishimoto, Y Goto, KI Suga Journal of Fermentation and Bioengineering 86 (5), 482-487, 1998 | 181 | 1998 |
Improved production of recombinant human antithrombin III in Chinese hamster ovary cells by ATF4 overexpression T Ohya, T Hayashi, E Kiyama, H Nishii, H Miki, K Kobayashi, K Honda, ... Biotechnology and bioengineering 100 (2), 317-324, 2008 | 121 | 2008 |
Amplified gene location in chromosomal DNA affected recombinant protein production and stability of amplified genes T Yoshikawa, F Nakanishi, Y Ogura, D Oi, T Omasa, Y Katakura, ... Biotechnology progress 16 (5), 710-715, 2000 | 120 | 2000 |
Synthetic metabolic engineering-a novel, simple technology for designing a chimeric metabolic pathway X Ye, K Honda, T Sakai, K Okano, T Omasa, R Hirota, A Kuroda, H Ohtake Microbial cell factories 11, 1-12, 2012 | 105 | 2012 |
Construction of BAC‐based physical map and analysis of chromosome rearrangement in Chinese hamster ovary cell lines Y Cao, S Kimura, T Itoi, K Honda, H Ohtake, T Omasa Biotechnology and Bioengineering 109 (6), 1357-1367, 2012 | 84 | 2012 |
Hyaluronic acid production by recombinant Streptococcus thermophilus N Izawa, M Serata, T Sone, T Omasa, H Ohtake Journal of bioscience and bioengineering 111 (6), 665-670, 2011 | 83 | 2011 |
Gene amplification and its application in cell and tissue engineering T Omasa Journal of bioscience and bioengineering 94 (6), 600-605, 2002 | 82 | 2002 |
Overexpression of GADD34 enhances production of recombinant human antithrombin III in Chinese hamster ovary cells T Omasa, T Takami, T Ohya, E Kiyama, T Hayashi, H Nishii, H Miki, ... Journal of bioscience and bioengineering 106 (6), 568-573, 2008 | 71 | 2008 |
Increase in desulfurization activity of Rhodococcus erythropolis KA2-5-1 using ethanol feeding H Yan, M Kishimoto, T Omasa, Y Katakura, KI Suga, K Okumura, ... Journal of bioscience and bioengineering 89 (4), 361-366, 2000 | 70 | 2000 |
Evaluation of stable and highly productive gene amplified CHO cell line based on the location of amplified genes T Yoshikawa, F Nakanishi, S Itami, D Kameoka, T Omasa, Y Katakura, ... Cytotechnology 33, 37-46, 2000 | 69 | 2000 |
Flow cytometry: an improved method for the selection of highly productive gene‐amplified CHO cells using flow cytometry T Yoshikawa, F Nakanishi, Y Ogura, D Oi, T Omasa, Y Katakura, ... Biotechnology and bioengineering 74 (5), 435-442, 2001 | 61 | 2001 |
The enhancement of specific antibody production rate in glucose-and glutamine-controlled fed-batch culture T Omasa, M Ishimoto, K Higashiyama, S Shioya, K Suga Cytotechnology 8, 75-84, 1992 | 58 | 1992 |
Optimization of cell line development in the GS-CHO expression system using a high-throughput, single cell-based clone selection system T Nakamura, T Omasa Journal of bioscience and bioengineering 120 (3), 323-329, 2015 | 57 | 2015 |
The osteoblastic differentiation ability of human dedifferentiated fat cells is higher than that of adipose stem cells from the buccal fat pad N Kishimoto, Y Momota, Y Hashimoto, S Tatsumi, K Ando, T Omasa, ... Clinical Oral Investigations 18, 1893-1901, 2014 | 57 | 2014 |
Extractive lactic acid fermentation with tri-n-decylamine as the extractant MT Gao, T Shimamura, N Ishida, E Nagamori, H Takahashi, S Umemoto, ... Enzyme and microbial technology 44 (5), 350-354, 2009 | 56 | 2009 |
In vivo estimation of bioartificial liver with recombinant HepG2 cells using pigs with ischemic liver failure S Enosawa, T Miyashita, Y Fujita, S Suzuki, H Amemiya, T Omasa, ... Cell transplantation 10 (4-5), 429-433, 2001 | 56 | 2001 |
Enhancement of sialylation on humanized IgG-like bispecific antibody by overexpression of α2, 6-sialyltransferase derived from Chinese hamster ovary cells M Onitsuka, WD Kim, H Ozaki, A Kawaguchi, K Honda, H Kajiura, ... Applied microbiology and biotechnology 94, 69-80, 2012 | 53 | 2012 |
Long-term culture of glutamine synthetase-transfected HepG2 cells in circulatory flow bioreactor for development of a bioartificial liver S Enosawa, T Miyashita, S Suzuki, XK Li, M Tsunoda, H Amemiya, ... Cell Transplantation 9 (5), 711-715, 2000 | 53 | 2000 |