| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13136* | 2021 |
| The COX-2/PGE 2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment A Greenhough, HJM Smartt, AE Moore, HR Roberts, AC Williams, ... Carcinogenesis 30 (3), 377-386, 2009 | 1481 | 2009 |
| Autolysosomal β‐catenin degradation regulates Wnt‐autophagy‐p62 crosstalk KJ Petherick, AC Williams, JD Lane, P Ordóñez‐Morán, J Huelsken, ... The EMBO journal 32 (13), 1903-1916, 2013 | 288 | 2013 |
| Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression DB Gurevich, CE Severn, C Twomey, A Greenhough, J Cash, AM Toye, ... The EMBO journal 37 (13), e97786, 2018 | 239 | 2018 |
| The cannabinoid δ9‐tetrahydrocannabinol inhibits RAS‐MAPK and PI3K‐AKT survival signalling and induces BAD‐mediated apoptosis in colorectal cancer cells A Greenhough, HA Patsos, AC Williams, C Paraskeva International journal of cancer 121 (10), 2172-2180, 2007 | 192 | 2007 |
| The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2 HA Patsos, DJ Hicks, RRH Dobson, A Greenhough, N Woodman, ... Gut 54 (12), 1741-1750, 2005 | 120 | 2005 |
| Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways AR Dallosso, B Øster, A Greenhough, K Thorsen, TJ Curry, C Owen, ... Oncogene 31 (40), 4409-4419, 2012 | 103 | 2012 |
| LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE 2 : implications for targeting adenoma stem cells with NSAIDs MRA Al-Kharusi, HJM Smartt, A Greenhough, TJ Collard, ED Emery, ... Carcinogenesis 34 (5), 1150-1157, 2013 | 88 | 2013 |
| The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells HA Patsos, A Greenhough, DJ Hicks, M Al Kharusi, TJ Collard, JD Lane, ... International journal of oncology 37 (1), 187-193, 2010 | 87 | 2010 |
| Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis A Greenhough, C Bagley, KJ Heesom, DB Gurevich, D Gay, M Bond, ... EMBO molecular medicine 10 (11), e8699, 2018 | 83 | 2018 |
| LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma GC Vieira, S Chockalingam, Z Melegh, A Greenhough, S Malik, ... Oncotarget 6 (37), 40053, 2015 | 79 | 2015 |
| HGF/Met signalling promotes PGE 2 biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells AE Moore, A Greenhough, HR Roberts, DJ Hicks, HA Patsos, AC Williams, ... Carcinogenesis 30 (10), 1796-1804, 2009 | 73 | 2009 |
| Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells JH Park, M Szemes, GC Vieira, Z Melegh, S Malik, KJ Heesom, ... Molecular oncology 9 (3), 617-627, 2015 | 68 | 2015 |
| Colon tumour cells increase PGE 2 by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation HR Roberts, HJM Smartt, A Greenhough, AE Moore, AC Williams, ... Carcinogenesis 32 (11), 1741-1747, 2011 | 65 | 2011 |
| β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells HJM Smartt, A Greenhough, P Ordóñez-Morán, E Talero, CA Cherry, ... Gut 61 (9), 1306-1314, 2012 | 63 | 2012 |
| Cannabinoids and cancer: potential for colorectal cancer therapy HA Patsos, DJ Hicks, A Greenhough, AC Williams, C Paraskeva Biochemical Society Transactions 33 (4), 712-714, 2005 | 57 | 2005 |
| BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling BC Urban, TJ Collard, CJ Eagle, SL Southern, A Greenhough, ... Gut 65 (7), 1151-1164, 2016 | 56 | 2016 |
| LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells RG Morgan, J Ridsdale, M Payne, KJ Heesom, MC Wilson, A Davidson, ... Haematologica 104 (7), 1365, 2019 | 54 | 2019 |
| LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells RG Morgan, J Ridsdale, M Payne, KJ Heesom, MC Wilson, A Davidson, ... Haematologica 104 (7), 1365, 2019 | 54 | 2019 |
| The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE2 signalling in colorectal adenoma cells A Greenhough, CA Wallam, DJ Hicks, M Moorghen, AC Williams, ... Oncogene 29 (23), 3398-3410, 2010 | 53 | 2010 |
