| Diabetes mellitus aggravates hemorrhagic transformation after ischemic stroke via mitochondrial defects leading to endothelial apoptosis K Mishiro, T Imai, S Sugitani, A Kitashoji, Y Suzuki, T Takagi, H Chen, ... PLoS One 9 (8), e103818, 2014 | 79 | 2014 |
| Intracellular Fe2+ accumulation in endothelial cells and pericytes induces blood-brain barrier dysfunction in secondary brain injury after brain hemorrhage T Imai, S Iwata, T Hirayama, H Nagasawa, S Nakamura, M Shimazawa, ... Scientific reports 9 (1), 6228, 2019 | 63 | 2019 |
| Cilostazol ameliorates collagenase-induced cerebral hemorrhage by protecting the blood–brain barrier T Takagi, T Imai, K Mishiro, M Ishisaka, M Tsujimoto, H Ito, K Nagashima, ... Journal of Cerebral Blood Flow & Metabolism 37 (1), 123-139, 2017 | 52 | 2017 |
| A novel nuclear factor erythroid 2-related factor 2 (Nrf2) activator RS9 attenuates brain injury after ischemia reperfusion in mice K Yamauchi, Y Nakano, T Imai, T Takagi, K Tsuruma, M Shimazawa, ... Neuroscience 333, 302-310, 2016 | 51 | 2016 |
| Nrf2 activator ameliorates hemorrhagic transformation in focal cerebral ischemia under warfarin anticoagulation T Imai, T Takagi, A Kitashoji, K Yamauchi, M Shimazawa, H Hara Neurobiology of disease 89, 136-146, 2016 | 45 | 2016 |
| Effects of ticagrelor in a mouse model of ischemic stroke K Yamauchi, T Imai, M Shimazawa, T Iwama, H Hara Scientific reports 7 (1), 1-10, 2017 | 36 | 2017 |
| A novel Nrf2 activator, RS9, attenuates secondary brain injury after intracerebral hemorrhage in sub-acute phase T Sugiyama, T Imai, S Nakamura, K Yamauchi, S Sawada, M Shimazawa, ... Brain research 1701, 137-145, 2018 | 34 | 2018 |
| Potential therapeutic effects of Nrf2 activators on intracranial hemorrhage T Imai, H Matsubara, H Hara Journal of Cerebral Blood Flow & Metabolism 41 (7), 1483-1500, 2021 | 29 | 2021 |
| The stroke preclinical assessment network: rationale, design, feasibility, and stage 1 results PD Lyden, F Bosetti, MA Diniz, A Rogatko, JI Koenig, J Lamb, ... Stroke 53 (5), 1802-1812, 2022 | 28 | 2022 |
| Protective effects of the astaxanthin derivative, adonixanthin, on brain hemorrhagic injury S Iwata, T Imai, M Shimazawa, T Ishibashi, M Hayashi, H Hara, ... Brain Research 1698, 130-138, 2018 | 27 | 2018 |
| Deferasirox, a trivalent iron chelator, ameliorates neuronal damage in hemorrhagic stroke models T Imai, S Tsuji, H Matsubara, T Ohba, T Sugiyama, S Nakamura, H Hara, ... Naunyn-Schmiedeberg's Archives of Pharmacology 394, 73-84, 2021 | 22 | 2021 |
| A novel free radical scavenger, NSP-116, ameliorated the brain injury in both ischemic and hemorrhagic stroke models T Imai, S Iwata, D Miyo, S Nakamura, M Shimazawa, H Hara Journal of pharmacological sciences 141 (3), 119-126, 2019 | 22 | 2019 |
| Antitumour effects of astaxanthin and adonixanthin on glioblastoma S Tsuji, S Nakamura, T Maoka, T Yamada, T Imai, T Ohba, T Yako, ... Marine drugs 18 (9), 474, 2020 | 21 | 2020 |
| The mitochondria-targeted peptide, bendavia, attenuated ischemia/reperfusion-induced stroke damage T Imai, H Matsubara, S Nakamura, H Hara, M Shimazawa Neuroscience 443, 110-119, 2020 | 21 | 2020 |
| Excess adiponectin in eyes with progressive ocular vascular diseases A Nishinaka, S Nakamura, M Tanaka, T Masuda, Y Inoue, T Yamamoto, ... The FASEB Journal 35 (2), e21313, 2021 | 17 | 2021 |
| A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke PD Lyden, MA Diniz, F Bosetti, J Lamb, KA Nagarkatti, A Rogatko, S Kim, ... Science translational medicine 15 (714), eadg8656, 2023 | 15 | 2023 |
| Protective effect of bendavia (SS-31) against oxygen/glucose-deprivation stress-induced mitochondrial damage in human brain microvascular endothelial cells T Imai, K Mishiro, T Takagi, A Isono, H Nagasawa, K Tsuruma, ... Current Neurovascular Research 14 (1), 53-59, 2017 | 15 | 2017 |
| Embracing heterogeneity in the multicenter Stroke Preclinical Assessment Network (SPAN) trial A Morais, JJ Locascio, LH Sansing, J Lamb, K Nagarkatti, T Imai, ... Stroke 54 (2), 620-631, 2023 | 14 | 2023 |
| Levetiracetam, an antiepileptic drug has neuroprotective effects on intracranial hemorrhage injury T Imai, T Sugiyama, S Iwata, S Nakamura, M Shimazawa, H Hara Neuroscience 431, 25-33, 2020 | 11 | 2020 |
| Therapeutic Effects of Iron Chelation in Atorvastatin-Induced Intracranial Hemorrhage of Zebrafish Larvae S Nakamura, Y Saito, T Gouda, T Imai, M Shimazawa, Y Nishimura, ... Journal of Stroke and Cerebrovascular Diseases 29 (11), 105215, 2020 | 7 | 2020 |
Hideko NagasawaGifu Pharmaceutical UniversityVerified email at gifu-pu.ac.jp
