Insights into naturally minimised Streptomyces albus J1074 genome N Zaburannyi, M Rabyk, B Ostash, V Fedorenko, A Luzhetskyy BMC genomics 15, 1-11, 2014 | 197 | 2014 |
Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity B Ostash, S Walker Natural product reports 27 (11), 1594-1617, 2010 | 196 | 2010 |
A streamlined metabolic pathway for the biosynthesis of moenomycin A B Ostash, A Saghatelian, S Walker Chemistry & biology 14 (3), 257-267, 2007 | 140 | 2007 |
Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics W Zhang, B Ostash, CT Walsh Proceedings of the National Academy of Sciences 107 (39), 16828-16833, 2010 | 117 | 2010 |
Complete characterization of the seventeen step moenomycin biosynthetic pathway B Ostash, EH Doud, C Lin, I Ostash, DL Perlstein, S Fuse, M Wolpert, ... Biochemistry 48 (37), 8830-8841, 2009 | 95 | 2009 |
Genetic factors that influence moenomycin production in streptomycetes R Makitrynskyy, Y Rebets, B Ostash, N Zaburannyi, M Rabyk, S Walker, ... Journal of Industrial Microbiology and Biotechnology 37 (6), 559-566, 2010 | 84 | 2010 |
Bacterial transglycosylase inhibitors B Ostash, S Walker Current opinion in chemical biology 9 (5), 459-466, 2005 | 84 | 2005 |
Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design Y Yuan, S Fuse, B Ostash, P Sliz, D Kahne, S Walker ACS chemical biology 3 (7), 429-436, 2008 | 80 | 2008 |
Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin R Makitrynskyy, B Ostash, O Tsypik, Y Rebets, E Doud, T Meredith, ... Open biology 3 (10), 130121, 2013 | 78 | 2013 |
Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus B Ostash, U Rix, LLR Rix, T Liu, F Lombo, A Luzhetskyy, O Gromyko, ... Chemistry & biology 11 (4), 547-555, 2004 | 78 | 2004 |
Identification of the Function of Gene l ndM2 Encoding a Bifunctional Oxygenase-Reductase Involved in the Biosynthesis of the Antitumor Antibiotic Landomycin E by Streptomyces … L Zhu, B Ostash, U Rix, M Nur-e-Alam, A Mayers, A Luzhetskyy, ... The Journal of organic chemistry 70 (2), 631-638, 2005 | 62 | 2005 |
Generation of novel landomycins M and O through targeted gene disruption A Luzhetskyy, L Zhu, M Gibson, M Fedoryshyn, C Dürr, C Hofmann, ... ChemBioChem 6 (4), 675-678, 2005 | 61 | 2005 |
Production of landomycins in Streptomyces globisporus 1912 and S. cyanogenus S136 is regulated by genes encoding putative transcriptional activators Y Rebets, B Ostash, A Luzhetskyy, D Hoffmeister, A Braňa, C Mendez, ... FEMS microbiology letters 222 (1), 149-153, 2003 | 59 | 2003 |
Interspecies conjugation of Escherichia coli-Streptomyces globisporus 1912 using integrative plasmid pSET152 and its derivatives AN Luzhetskiĭ, BE Ostash, VA Fedorenko Genetika 37 (10), 1340-1347, 2001 | 56* | 2001 |
On the acceptor substrate of C-glycosyltransferase UrdGT2: three prejadomycin C-glycosides from an engineered mutant of Streptomyces globisporus 1912 ΔlndE (urdGT2) I Baig, M Kharel, A Kobylyanskyy, L Zhu, Y Rebets, B Ostash, ... Angewandte Chemie (International ed. in English) 45 (46), 7842, 2006 | 55 | 2006 |
Streptomyces ghanaensis pleiotropic regulatory gene wblA gh influences morphogenesis and moenomycin production M Rabyk, B Ostash, Y Rebets, S Walker, V Fedorenko Biotechnology letters 33, 2481-2486, 2011 | 47 | 2011 |
Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136 I Ostash, B Ostash, A Luzhetskyy, A Bechthold, S Walker, V Fedorenko FEMS microbiology letters 285 (2), 195-202, 2008 | 45 | 2008 |
Chemistry and biology of landomycins, an expanding family of polyketide natural products B Ostash, A Korynevska, R Stoika, V Fedorenko Mini reviews in medicinal chemistry 9 (9), 1040-1051, 2009 | 43 | 2009 |
IncP plasmids are most effective in mediating conjugation between Escherichia coli and streptomycetes A Luzhetskyy, M Fedoryshyn, O Gromyko, B Ostash, Y Rebets, ... Russian Journal of Genetics 42, 476-481, 2006 | 42 | 2006 |
Expression of the regulatory protein LndI for landomycin E production in Streptomyces globisporus 1912 is controlled by the availability of tRNA for the rare UUA … YV Rebets, BO Ostash, M Fukuhara, T Nakamura, VO Fedorenko FEMS microbiology letters 256 (1), 30-37, 2006 | 41 | 2006 |