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James R Hawley
James R Hawley
Senior Computational Biologist at Roche
Verified email at roche.com - Homepage
Title
Cited by
Cited by
Year
Spatial genomic heterogeneity within localized, multifocal prostate cancer
PC Boutros, M Fraser, NJ Harding, R De Borja, D Trudel, E Lalonde, ...
Nature genetics 47 (7), 736-745, 2015
5282015
Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer
S Zhou, JR Hawley, F Soares, G Grillo, M Teng, SA Madani Tonekaboni, ...
Nature communications 11 (1), 441, 2020
692020
The mitochondrial transacylase, tafazzin, regulates aml stemness by modulating intracellular levels of phospholipids
AK Seneviratne, M Xu, JJA Henao, VA Fajardo, Z Hao, V Voisin, GW Xu, ...
Cell stem cell 24 (4), 621-636. e16, 2019
542019
Disrupting mitochondrial copper distribution inhibits leukemic stem cell self-renewal
RP Singh, DV Jeyaraju, V Voisin, R Hurren, C Xu, JR Hawley, ...
Cell stem cell 26 (6), 926-937. e10, 2020
442020
Reorganization of the 3D Genome Pinpoints Noncoding Drivers of Primary Prostate TumorsThe Three-Dimensional Genome of Primary Prostate Cancer
JR Hawley, S Zhou, C Arlidge, G Grillo, KJ Kron, R Hugh-White, ...
Cancer Research 81 (23), 5833-5848, 2021
13*2021
Transposable elements are co-opted as oncogenic regulatory elements by lineage-specific transcription factors in prostate cancer
G Grillo, T Keshavarzian, S Linder, C Arlidge, L Mout, A Nand, M Teng, ...
Cancer discovery 13 (11), 2470-2487, 2023
92023
Chronic hypoxia favours adoption to a castration-resistant cell state in prostate cancer
S Cameron, G Deblois, JR Hawley, A Qamra, S Zhou, SAM Tonekaboni, ...
Oncogene 42 (21), 1693-1703, 2023
62023
Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer
S El Ghamrasni, R Quevedo, J Hawley, P Mazrooei, Y Hanna, I Cirlan, ...
Molecular Cancer Research 20 (1), 102-113, 2022
32022
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer
SG Zhao, M Bootsma, S Zhou, R Shrestha, T Moreno-Rodriguez, ...
Nature Genetics, 1-12, 2024
2024
Chronic hypoxia favours adoption to a castration-resistant cell state in prostate cancer
M Lupien, S Cameron, G Deblois, J Hawley, A Qamra, S Zhou, ...
2022
Non-coding mutations reveal cancer driver cistromes in luminal breast cancer
SE Ghamrasni, R Quevedo, J Hawley, P Mazrooei, Y Hanna, I Cirlan, ...
bioRxiv, 2021.05. 29.446210, 2021
2021
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Articles 1–11