Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts J Albrengues, T Bertero, E Grasset, S Bonan, M Maiel, I Bourget, ... Nature communications 6 (1), 10204, 2015 | 336 | 2015 |
Rho GTPases modulate malignant transformation of tumor cells JL Orgaz, C Herraiz, V Sanz-Moreno Small GTPases 5 (4), e983867, 2014 | 195 | 2014 |
Regional activation of myosin II in cancer cells drives tumor progression via a secretory cross-talk with the immune microenvironment M Georgouli, C Herraiz, E Crosas-Molist, B Fanshawe, O Maiques, ... Cell 176 (4), 757-774. e23, 2019 | 143 | 2019 |
Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT C Herraiz, F Journe, Z Abdel-Malek, G Ghanem, C Jiménez-Cervantes, ... Molecular endocrinology 25 (1), 138-156, 2011 | 128 | 2011 |
MC1R signaling. Intracellular partners and pathophysiological implications C Herraiz, JC Garcia-Borron, C Jiménez-Cervantes, C Olivares Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (10 …, 2017 | 115 | 2017 |
Identification and functional analysis of novel variants of the human melanocortin 1 receptor found in melanoma patients AB Perez Oliva, LP Fernéndez, C DeTorre, C Herráiz, ... Human mutation 30 (5), 811-822, 2009 | 77 | 2009 |
Anti-folate receptor-α IgE but not IgG recruits macrophages to attack tumors via TNFα/MCP-1 signaling DH Josephs, HJ Bax, T Dodev, M Georgouli, M Nakamura, G Pellizzari, ... Cancer research 77 (5), 1127-1141, 2017 | 73 | 2017 |
The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination E Crosas-Molist, E Bertran, I Rodriguez-Hernandez, C Herraiz, G Cantelli, ... Oncogene 36 (21), 3002-3014, 2017 | 67 | 2017 |
Reactivation of p53 by a cytoskeletal sensor to control the balance between DNA damage and tumor dissemination C Herraiz, F Calvo, P Pandya, G Cantelli, I Rodriguez-Hernandez, ... Journal of the National Cancer Institute 108 (1), djv289, 2016 | 65 | 2016 |
Melanocortin 1 receptor mutations impact differentially on signalling to the cAMP and the ERK mitogen-activated protein kinase pathways C Herraiz, C Jiménez-Cervantes, P Zanna, JC García-Borrón FEBS letters 583 (19), 3269-3274, 2009 | 64 | 2009 |
Aberrant trafficking of human melanocortin 1 receptor variants associated with red hair and skin cancer: Steady‐state retention of mutant forms in the proximal golgi BL Sánchez‐Laorden, C Herraiz, JC Valencia, VJ Hearing, ... Journal of cellular physiology 220 (3), 640-654, 2009 | 56 | 2009 |
Mechanism of dimerization of the human melanocortin 1 receptor PT Zanna, BL Sánchez-Laorden, AB Pérez-Oliva, MC Turpín, C Herraiz, ... Biochemical and biophysical research communications 368 (2), 211-216, 2008 | 44 | 2008 |
cAMP-independent non-pigmentary actions of variant melanocortin 1 receptor: AKT-mediated activation of protective responses to oxidative DNA damage M Castejon-Grinan, C Herraiz, C Olivares, C Jimenez-Cervantes, ... Oncogene 37 (27), 3631-3646, 2018 | 39 | 2018 |
Differential and competitive regulation of human melanocortin 1 receptor signaling by β-arrestin isoforms M Abrisqueta, C Herraiz, AB Perez Oliva, BL Sanchez-Laorden, ... Journal of cell science 126 (16), 3724-3737, 2013 | 38 | 2013 |
Functional status and relationships of melanocortin 1 receptor signaling to the cAMP and extracellular signal-regulated protein kinases 1 and 2 pathways in human melanoma cells C Herraiz, F Journé, G Ghanem, C Jiménez-Cervantes, JC García-Borrón The international journal of biochemistry & cell biology 44 (12), 2244-2252, 2012 | 37 | 2012 |
The α‐melanocyte‐stimulating hormone/melanocortin‐1 receptor interaction: A driver of pleiotropic effects beyond pigmentation C Herraiz, I Martínez‐Vicente, V Maresca Pigment cell & melanoma research 34 (4), 748-761, 2021 | 33 | 2021 |
Functional interplay between secreted ligands and receptors in melanoma C Herraiz, C Jiménez-Cervantes, B Sánchez-Laorden, JC García-Borrón Seminars in cell & developmental biology 78, 73-84, 2018 | 26 | 2018 |
Functional characterization of MC1R-TUBB3 intergenic splice variants of the human melanocortin 1 receptor C Herraiz, C Olivares, M Castejon-Grinan, M Abrisqueta, ... PloS one 10 (12), e0144757, 2015 | 20 | 2015 |
N‐glycosylation of the human melanocortin 1 receptor: occupancy of glycosylation sequons and functional role C Herraiz, BL Sánchez‐Laorden, C Jiménez‐Cervantes, ... Pigment Cell & Melanoma Research 24 (3), 479-489, 2011 | 20 | 2011 |
Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase M Abrisqueta, C Olivares, C Herraiz, M Castejón-Griñán, J Sirés-Campos, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (1), 76-94, 2018 | 10 | 2018 |