Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model T Kikuchi, A Morizane, D Doi, H Magotani, H Onoe, T Hayashi, H Mizuma, ... Nature 548 (7669), 592-596, 2017 | 681 | 2017 |
Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation D Doi, B Samata, M Katsukawa, T Kikuchi, A Morizane, Y Ono, ... Stem cell reports 2 (3), 337-350, 2014 | 480 | 2014 |
Direct comparison of autologous and allogeneic transplantation of iPSC-derived neural cells in the brain of a nonhuman primate A Morizane, D Doi, T Kikuchi, K Okita, A Hotta, T Kawasaki, T Hayashi, ... Stem cell reports 1 (4), 283-292, 2013 | 313 | 2013 |
Pre-clinical study of induced pluripotent stem cell-derived dopaminergic progenitor cells for Parkinson’s disease D Doi, H Magotani, T Kikuchi, M Ikeda, S Hiramatsu, K Yoshida, N Amano, ... Nature communications 11 (1), 1-14, 2020 | 238 | 2020 |
MHC matching improves engraftment of iPSC-derived neurons in non-human primates A Morizane, T Kikuchi, T Hayashi, H Mizuma, S Takara, H Doi, A Mawatari, ... Nature communications 8 (1), 385, 2017 | 234 | 2017 |
Prolonged maturation culture favors a reduction in the tumorigenicity and the dopaminergic function of human ESC‐derived neural cells in a primate model of Parkinson's disease D Doi, A Morizane, T Kikuchi, H Onoe, T Hayashi, T Kawasaki, M Motono, ... Stem cells 30 (5), 935-945, 2012 | 212 | 2012 |
Small‐molecule inhibitors of bone morphogenic protein and activin/nodal signals promote highly efficient neural induction from human pluripotent stem cells A Morizane, D Doi, T Kikuchi, K Nishimura, J Takahashi Journal of neuroscience research 89 (2), 117-126, 2011 | 201 | 2011 |
Survival of human induced pluripotent stem cell–derived midbrain dopaminergic neurons in the brain of a primate model of Parkinson's disease T Kikuchi, A Morizane, H Onoe, T Hayashi, T Kawasaki, H Saiki, ... Journal of Parkinson's disease 1 (4), 395-412, 2011 | 152 | 2011 |
Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1 B Samata, D Doi, K Nishimura, T Kikuchi, A Watanabe, Y Sakamoto, ... Nature communications 7, 13097, 2016 | 108 | 2016 |
Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level X Yuan, M Schröter, MEJ Obien, M Fiscella, W Gong, T Kikuchi, ... Nature communications 11 (1), 1-14, 2020 | 68 | 2020 |
Axonal Extensions along Corticospinal Tracts from Transplanted Human Cerebral Organoids T Kitahara, H Sakaguchi, A Morizane, T Kikuchi, S Miyamoto, J Takahashi Stem Cell Reports, 2020 | 55 | 2020 |
Idiopathic Parkinson's disease patient‐derived induced pluripotent stem cells function as midbrain dopaminergic neurons in rodent brains T Kikuchi, A Morizane, D Doi, K Okita, M Nakagawa, H Yamakado, ... Journal of neuroscience research 95 (9), 1829-1837, 2017 | 41 | 2017 |
X-linked severe combined immunodeficiency (X-SCID) rats for xeno-transplantation and behavioral evaluation B Samata, T Kikuchi, Y Miyawaki, A Morizane, T Mashimo, M Nakagawa, ... Journal of neuroscience methods 243, 68-77, 2015 | 25 | 2015 |
Therapeutic effects of combined cell transplantation and locomotor training in rats with brain injury T Shimogawa, H Sakaguchi, T Kikuchi, R Tsuchimochi, N Sano, ... npj Regenerative Medicine 4 (1), 13, 2019 | 11 | 2019 |
Zonisamide promotes survival of human‐induced pluripotent stem cell‐derived dopaminergic neurons in the striatum of female rats Y Miyawaki, B Samata, T Kikuchi, K Nishimura, J Takahashi Journal of Neuroscience Research, 2020 | 8 | 2020 |
Clinically compatible differentiation protocol for human pluripotent stem cell-derived dopaminergic progenitor cells D Doi, T Kikuchi, A Morizane, J Takahashi | 2 | 2020 |
Preparation of biological samples for the recording of electrophysiological signals using high-density microelectrode arrays X Yuan, M Schröter, MEJ Obien, M Fiscella, W Gong, T Kikuchi, ... | 1 | 2020 |
Microsyringe unit J Takahashi, D Doi, T Kikuchi, K Kato US Patent App. 17/262,944, 2021 | | 2021 |
Clinically compatible differentiation protocol for human pluripotent stem cell-derived dopaminergic progenitor cells T Kikuchi, A Morizane, J Takahashi | | 2020 |
ips cell modeling of genetic Parkinson's disease: 160 Y Koshiba, H Yamakado, A Morizane, T Kikuchi, K Hasegawa, H Inoue, ... Movement Disorders 29, S68, 2014 | | 2014 |