Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing MM Karunakaran, CR Willcox, M Salim, D Paletta, AS Fichtner, A Noll, ... Immunity, 2020 | 196 | 2020 |
Vγ9Vδ2 TCR‐activation by phosphorylated antigens requires butyrophilin 3 A1 (BTN3A1) and additional genes on human chromosome 6 F Riaño, MM Karunakaran, L Starick, J Li, CJ Scholz, V Kunzmann, ... European journal of immunology 44 (9), 2571-2576, 2014 | 92 | 2014 |
Vγ9 and Vδ2 T cell antigen receptor genes and butyrophilin 3 (BTN3) emerged with placental mammals and are concomitantly preserved in selected species like alpaca (Vicugna pacos) MM Karunakaran, TW Göbel, L Starick, L Walter, T Herrmann Immunogenetics 66 (4), 243-254, 2014 | 75 | 2014 |
Butyrophilin 3A (BTN3A, CD277)‐specific antibody 20.1 differentially activates Vγ9Vδ2 TCR clonotypes and interferes with phosphoantigen activation L Starick, F Riano, MM Karunakaran, V Kunzmann, J Li, M Kreiss, ... European Journal of Immunology 47 (6), 982-992, 2017 | 57 | 2017 |
The Vγ9Vδ2 T Cell Antigen Receptor and Butyrophilin-3 A1: Models of Interaction, the Possibility of Co-Evolution, and the Case of Dendritic Epidermal T Cells MM Karunakaran, T Herrmann Frontiers in immunology 5, 2014 | 51 | 2014 |
An Update on the Molecular Basis of Phosphoantigen Recognition by Vγ9Vδ2 T Cells T Herrmann, AS Fichtner, MM Karunakaran Cells 9 (6), 1433, 2020 | 45 | 2020 |
Alpaca (Vicugna pacos), the first nonprimate species with a phosphoantigen-reactive Vγ9Vδ2 T cell subset AS Fichtner, MM Karunakaran, S Gu, CT Boughter, MT Borowska, ... Proceedings of the National Academy of Sciences, 2020 | 24 | 2020 |
A glance over the fence: Using phylogeny and species comparison for a better understanding of antigen recognition by human γδ T‐cells T Herrmann, MM Karunakaran, AS Fichtner Immunological reviews 298 (1), 218-236, 2020 | 21 | 2020 |
Butyrophilins: γδ T cell receptor ligands, immunomodulators and more T Herrmann, MM Karunakaran Frontiers in Immunology 13, 876493, 2022 | 20 | 2022 |
The Armadillo (Dasypus novemcinctus): a witness but not a functional example for the emergence of the butyrophilin 3 (BTN3)/Vγ9Vδ2 system in placental mammals AS Fichtner, MM Karunakaran, RW Truman, T Herrmann Frontiers in Immunology 9, 265, 2018 | 14 | 2018 |
Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1 CR Willcox, M Salim, CR Begley, MM Karunakaran, EJ Easton, ... Cell Reports 42 (4), 2023 | 12 | 2023 |
Evolution of Vγ9Vδ2 T-cells MM Karunakaran | 6 | 2014 |
Die Evolution der Vγ9Vδ2 T-Zellen The Evolution of Vγ9Vδ2 T Cells MM Karunakaran | 6* | |
A photocrosslinkable biotin derivative of the phosphoantigen (E)‐4‐hydroxy‐3‐methylbut‐2‐enyl diphosphate (HMBPP) activates Vγ9Vδ2 T cells and binds to the HMBPP site of BTN3A1 A Mattarei, M Enzinger, S Gu, MM Karunakaran, B Kimmel, N Berner, ... Chemistry-A European Journal, 2017 | 5 | 2017 |
A distinct topology of BTN3A IgV and B30. 2 domains controlled by juxtamembrane regions favors optimal human γδ T cell phosphoantigen sensing MM Karunakaran, H Subramanian, Y Jin, F Mohammed, B Kimmel, ... Nature Communications 14 (1), 7617, 2023 | 2 | 2023 |