Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model PM Keeney, CK Quigley, LD Dunham, CM Papageorge, S Iyer, ... Human gene therapy 20 (8), 897-907, 2009 | 105 | 2009 |
Short telomeres in yeast are highly recombinogenic MJ McEachern, S Iyer Molecular cell 7 (4), 695-704, 2001 | 98 | 2001 |
Telomere fusions caused by mutating the terminal region of telomeric DNA MJ McEachern, S Iyer, TB Fulton, EH Blackburn Proceedings of the National Academy of Sciences 97 (21), 11409-11414, 2000 | 89 | 2000 |
Mitochondrial gene therapy improves respiration, biogenesis, and transcription in G11778A Leber's hereditary optic neuropathy and T8993G Leigh's syndrome cells S Iyer, K Bergquist, K Young, E Gnaiger, RR Rao, JP Bennett Jr Human gene therapy 23 (6), 647-657, 2012 | 66 | 2012 |
Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression S Iyer, RR Thomas, FR Portell, LD Dunham, CK Quigley, JP Bennett Jr Mitochondrion 9 (3), 196-203, 2009 | 66 | 2009 |
Leigh syndrome: A tale of two genomes AB Bakare, EJ Lesnefsky, S Iyer Frontiers in Physiology, 1286, 2021 | 60 | 2021 |
A mutation in the STN1 gene triggers an alternative lengthening of telomere-like runaway recombinational telomere elongation and rapid deletion in yeast S Iyer, AD Chadha, MJ McEachern Molecular and cellular biology, 2005 | 48 | 2005 |
Mitochondrial physiology: Mitochondrial respiratory states and rates E Gnaiger, M TaskGroup Bioenergetics Communications 2020, doi.org/10.26124/bec:2020-0001.v1, 2020 | 47* | 2020 |
The saga of endocrine FGFs P Phan, BB Saikia, S Sonnaila, S Agrawal, Z Alraawi, TKS Kumar, S Iyer Cells 10 (9), 2418, 2021 | 38 | 2021 |
Mitochondrial gene replacement in human pluripotent stem cell-derived neural progenitors S Iyer, E Xiao, K Alsayegh, N Eroshenko, MJ Riggs, JP Bennett, RR Rao Gene therapy 19 (5), 469-475, 2012 | 31 | 2012 |
The Role Of Nonhomologous End-Joining Components in Telomere Metabolism in Kluyveromyces lactis SD Carter, S Iyer, J Xu, MJ McEachern, SU Åström Genetics 175 (3), 1035-1045, 2007 | 26 | 2007 |
Novel therapeutic approaches for Leber’s hereditary optic neuropathy S Iyer Discovery medicine 15 (82), 141, 2013 | 25 | 2013 |
Quantifying mitochondrial dynamics in patient fibroblasts with multiple developmental defects and mitochondrial disorders AB Bakare, J Daniel, J Stabach, A Rojas, A Bell, B Henry, S Iyer International Journal of Molecular Sciences 22 (12), 6263, 2021 | 20 | 2021 |
Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination EY Basenko, AJ Cesare, S Iyer, JD Griffith, MJ McEachern Nucleic acids research 38 (1), 182-189, 2010 | 20 | 2010 |
mRNA reprogramming of T8993G Leigh's syndrome fibroblast cells to create induced pluripotent stem cell models for mitochondrial disorders HE Grace, P Galdun III, EJ Lesnefsky, FD West, S Iyer Stem cells and development 28 (13), 846-859, 2019 | 19 | 2019 |
Quantitative analysis of mitochondrial morphologies in human induced pluripotent stem cells for Leigh syndrome F Meshrkey, AC Ayuso, RR Rao, S Iyer Stem cell research 57, 102572, 2021 | 15 | 2021 |
Stem cell-based models and therapies for neurodegenerative diseases S Iyer, K Alsayegh, S Abraham, RR Rao Critical Reviews™ in Biomedical Engineering 37 (4-5), 2009 | 14 | 2009 |
Knockdown of CDK2AP1 in primary human fibroblasts induces p53 dependent senescence KN Alsayegh, VS Gadepalli, S Iyer, RR Rao PLoS One 10 (3), e0120782, 2015 | 13 | 2015 |
Knockdown of CDK2AP1 in human embryonic stem cells reduces the threshold of differentiation KN Alsayegh, SD Sheridan, S Iyer, RR Rao PloS one 13 (5), e0196817, 2018 | 9 | 2018 |
Cell-permeable succinate increases mitochondrial membrane potential and glycolysis in leigh syndrome patient fibroblasts AB Bakare, RR Rao, S Iyer Cells 10 (9), 2255, 2021 | 8 | 2021 |