| Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex YL Liang, M Khoshouei, A Glukhova, SGB Furness, P Zhao, L Clydesdale, ... Nature 555 (7694), 121-125, 2018 | 300 | 2018 |
| Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism S Lei, L Clydesdale, A Dai, X Cai, Y Feng, D Yang, YL Liang, C Koole, ... Journal of Biological Chemistry 293 (24), 9370-9387, 2018 | 49 | 2018 |
| Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation AD White, KA Peña, LJ Clark, CS Maria, S Liu, FG Jean-Alphonse, JY Lee, ... Science signaling 14 (703), eabc5944, 2021 | 48 | 2021 |
| Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation LJ Clark, J Krieger, AD White, V Bondarenko, S Lei, F Fang, JY Lee, ... Nature chemical biology 16 (10), 1096-1104, 2020 | 40 | 2020 |
| Clinical perspectives of isoniazid-induced liver injury S Lei, R Gu, X Ma Liver Research 5 (2), 45-52, 2021 | 29 | 2021 |
| G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cells C Zhou, X Dai, Y Chen, Y Shen, S Lei, T Xiao, T Bartfai, J Ding, MW Wang Oncotarget 7 (11), 12823, 2016 | 27 | 2016 |
| Precise druggability of the PTH type 1 receptor I Sutkeviciute, JY Lee, AD White, CS Maria, KA Peña, S Savransky, ... Nature chemical biology 18 (3), 272-280, 2022 | 17 | 2022 |
| Application of chemical biology in target identification and drug discovery Y Zhu, T Xiao, S Lei, F Zhou, MW Wang Archives of pharmacal research 38, 1642-1650, 2015 | 14 | 2015 |
| PPARγ regulates triclosan induced placental dysfunction J Li, X Quan, Y Zhang, T Yu, S Lei, Z Huang, Q Wang, W Song, X Yang, ... Cells 11 (1), 86, 2021 | 13 | 2021 |
| PFOS Inhibited Normal Functional Development of Placenta Cells via PPARγ Signaling J Li, X Quan, S Lei, Z Huang, Q Wang, P Xu Biomedicines 9 (6), 677, 2021 | 13 | 2021 |
| LncRNA MEG3 alleviates PFOS induced placental cell growth inhibition through its derived miR-770 targeting PTX3 J Li, X Quan, S Lei, G Chen, J Hong, Z Huang, Q Wang, W Song, X Yang Environmental Pollution 293, 118542, 2022 | 9 | 2022 |
| Iron metabolism mediates the relationship between Vitamin C and hepatic steatosis and fibrosis in NAFLD Z Hu, Y Li, B Ma, S Lei, X Wang Frontiers in Nutrition 9, 952056, 2022 | 5 | 2022 |
| Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors J Zhu, S Lei, J Lu, Y Hao, Q Qian, AS Devanathan, Z Feng, XQ Xie, P Wipf, ... European Journal of Medicinal Chemistry 259, 115666, 2023 | 3 | 2023 |
| Role of CYP2A6 in methimazole bioactivation and hepatotoxicity J Li, Z Hussain, J Zhu, S Lei, J Lu, X Ma Chemical research in toxicology 34 (12), 2534-2539, 2021 | 3 | 2021 |
| Chemical basis of pregnane X receptor activators in the herbal supplement Gancao (licorice) A Cheng, S Lei, J Zhu, J Lu, MF Paine, W Xie, X Ma Liver Research 6 (4), 251-257, 2022 | 2 | 2022 |
| Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) and Uncaria tomentosa (Cat’s Claw) S Lei, J Lu, A Cheng, Z Hussain, K Tidgewell, J Zhu, X Ma Drug Metabolism and Disposition 51 (5), 629-636, 2023 | 1 | 2023 |
| Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in β-arrestin 1/2 signaling S Lei, Q Meng, Y Liu, Q Liu, A Dai, X Cai, MW Wang, Q Zhou, H Zhou, ... European Journal of Pharmacology, 176419, 2024 | | 2024 |
| Activation of PXR causes drug interactions with Paxlovid in transgenic mice S Lei, A Guo, J Lu, Q Qi, AS Devanathan, J Zhu, X Ma Acta Pharmaceutica Sinica B 13 (11), 4502-4510, 2023 | | 2023 |
| Precision druggability of a class B GPCR, the PTH type 1 receptor I Sutkeviciute, JY Lee, A White, P Doruker, K Pena, S Sanker, S Lei, ... The FASEB Journal 35, 2021 | | 2021 |
| A historic study that opened a new chapter in nutritional science S Lei, D Yang, M Wang Acta Pharmacologica Sinica 37 (12), 1641-1644, 2016 | | 2016 |
