| Ruthenium-catalyzed alkene-alkyne coupling: Synthesis of the proposed structure of amphidinolide A BM Trost, JD Chisholm, ST Wrobleski, M Jung Journal of the American Chemical Society 124 (42), 12420-12421, 2002 | 130 | 2002 |
| Therapeutic potential of SH2 domain-containing inositol-5′-phosphatase 1 (SHIP1) and SHIP2 inhibition in cancer GM Fuhler, R Brooks, B Toms, S Iyer, EA Gengo, MY Park, M Gumbleton, ... Molecular medicine 18, 65-75, 2012 | 128 | 2012 |
| The next generation of immunotherapy for cancer: small molecules could make big waves WG Kerr, JD Chisholm The Journal of Immunology 202 (1), 11-19, 2019 | 103 | 2019 |
| Total synthesis of (+)-amphidinolide A. Assembly of the fragments BM Trost, ST Wrobleski, JD Chisholm, PE Harrington, M Jung Journal of the American Chemical Society 127 (39), 13589-13597, 2005 | 94 | 2005 |
| An acid-catalyzed macrolactonization protocol BM Trost, JD Chisholm Organic letters 4 (21), 3743-3745, 2002 | 92 | 2002 |
| RebG‐and RebM‐catalyzed indolocarbazole diversification C Zhang, C Albermann, X Fu, NR Peters, JD Chisholm, G Zhang, ... ChemBioChem 7 (5), 795-804, 2006 | 91 | 2006 |
| Total synthesis of (+)-amphidinolide A. Structure elucidation and completion of the synthesis BM Trost, PE Harrington, JD Chisholm, ST Wrobleski Journal of the American Chemical Society 127 (39), 13598-13610, 2005 | 76 | 2005 |
| Discovery and development of small molecule SHIP phosphatase modulators DR Viernes, LB Choi, WG Kerr, JD Chisholm Medicinal research reviews 34 (4), 795-824, 2014 | 66 | 2014 |
| Addition of Alkynes to Aldehydes and Activated Ketones Catalyzed by Rhodium− Phosphine Complexes PK Dhondi, P Carberry, LB Choi, JD Chisholm The Journal of Organic Chemistry 72 (25), 9590-9596, 2007 | 64 | 2007 |
| Rhodium-catalyzed addition of alkynes to activated ketones and aldehydes PK Dhondi, JD Chisholm Organic Letters 8 (1), 67-69, 2006 | 62 | 2006 |
| Regiocontrolled synthesis of the antitumor antibiotic AT2433-A1 JD Chisholm, DL Van Vranken The Journal of organic chemistry 65 (22), 7541-7553, 2000 | 62 | 2000 |
| Targeting SHIP-1 in myeloid cells enhances trained immunity and boosts response to infection P Saz-Leal, C Del Fresno, P Brandi, S Martinez-Cano, OM Dungan, ... Cell reports 25 (5), 1118-1126, 2018 | 61 | 2018 |
| Rhodium-catalyzed 1, 4-addition of terminal alkynes to vinyl ketones RV Lerum, JD Chisholm Tetrahedron letters 45 (35), 6591-6594, 2004 | 58 | 2004 |
| DNA sequence recognition by the indolocarbazole antitumor antibiotic AT2433-B1 and its diastereoisomer C Carrasco, M Facompré, JD Chisholm, DL Van Vranken, WD Wilson, ... Nucleic acids research 30 (8), 1774-1781, 2002 | 58 | 2002 |
| Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation E Hoekstra, AM Das, M Willemsen, M Swets, PJK Kuppen, ... Oncotarget 7 (45), 73525, 2016 | 53 | 2016 |
| Conformational control in the rebeccamycin class of indolocarbazole glycosides EJ Gilbert, JD Chisholm, DL Van Vranken The Journal of Organic Chemistry 64 (15), 5670-5676, 1999 | 51 | 1999 |
| Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis C Pedicone, S Fernandes, OM Dungan, SM Dormann, DR Viernes, ... Journal of cell science 133 (5), jcs238030, 2020 | 46 | 2020 |
| Tandem oxidation/halogenation of aryl allylic alcohols under Moffatt− Swern conditions J Yin, CE Gallis, JD Chisholm The Journal of Organic Chemistry 72 (18), 7054-7057, 2007 | 44 | 2007 |
| DNA binding and topoisomerase I poisoning activities of novel disaccharide indolocarbazoles M Facompre, C Carrasco, P Colson, C Houssier, JD Chisholm, ... Molecular pharmacology 62 (5), 1215-1227, 2002 | 44 | 2002 |
| Phosphorylation and ubiquitination regulate protein phosphatase 5 activity and its prosurvival role in kidney cancer N Dushukyan, DM Dunn, RA Sager, MR Woodford, DR Loiselle, ... Cell reports 21 (7), 1883-1895, 2017 | 42 | 2017 |
