| Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer’s disease mice FJ Bustos, E Ampuero, N Jury, R Aguilar, F Falahi, J Toledo, J Ahumada, ... Brain 140 (12), 3252-3268, 2017 | 142 | 2017 |
| Epigenetic control of the bone-master Runx2 gene during osteoblast-lineage commitment by the histone demethylase JARID1B/KDM5B A Rojas, R Aguilar, B Henriquez, JB Lian, JL Stein, GS Stein, ... Journal of biological chemistry 290 (47), 28329-28342, 2015 | 94 | 2015 |
| Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons B Henriquez, FJ Bustos, R Aguilar, A Becerra, F Simon, M Montecino, ... Molecular and Cellular Neuroscience 57, 130-143, 2013 | 74 | 2013 |
| The specification of cortical subcerebral projection neurons depends on the direct repression of TBR1 by CTIP1/BCL11a J Cánovas, FA Berndt, H Sepúlveda, R Aguilar, FA Veloso, M Montecino, ... Journal of Neuroscience 35 (19), 7552-7564, 2015 | 72 | 2015 |
| Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space NF Rizvi, JP Santa Maria Jr, A Nahvi, J Klappenbach, DJ Klein, PJ Curran, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (4), 384-396, 2020 | 69 | 2020 |
| Targeting Xist with compounds that disrupt RNA structure and X inactivation R Aguilar, KB Spencer, B Kesner, NF Rizvi, MD Badmalia, T Mrozowich, ... Nature 604 (7904), 160-166, 2022 | 58 | 2022 |
| Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons C Arredondo, C Cefaliello, A Dyrda, N Jury, P Martinez, I Díaz, A Amaro, ... Neuron 110 (10), 1656-1670. e12, 2022 | 42 | 2022 |
| Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops HJ Oh, R Aguilar, B Kesner, HG Lee, AJ Kriz, HP Chu, JT Lee Cell 184 (25), 6157-6173. e24, 2021 | 42 | 2021 |
| Epigenetic Signatures at the RUNX2‐P1 and Sp7 Gene Promoters Control Osteogenic Lineage Commitment of Umbilical Cord‐Derived Mesenchymal Stem Cells H Sepulveda, R Aguilar, CP Prieto, F Bustos, S Aedo, J Lattus, ... Journal of cellular physiology 232 (9), 2519-2527, 2017 | 32 | 2017 |
| The chromatin modifying complex CoREST/LSD1 negatively regulates notch pathway during cerebral cortex development CI Lopez, KE Saud, R Aguilar, FA Berndt, J Cánovas, M Montecino, ... Developmental neurobiology 76 (12), 1360-1373, 2016 | 28 | 2016 |
| Multiple levels of epigenetic control for bone biology and pathology M Montecino, G Stein, J Stein, K Zaidi, R Aguilar Bone 81, 733-738, 2015 | 26 | 2015 |
| Mll‐COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts A Rojas, H Sepulveda, B Henriquez, R Aguilar, T Opazo, G Nardocci, ... Journal of cellular physiology 234 (5), 6244-6253, 2019 | 20 | 2019 |
| The Ric-8B Gene is highly expressed in proliferating preosteoblastic cells and downregulated during osteoblast differentiation in a SWI/SNF-and C/EBPβ-mediated manner R Grandy, H Sepulveda, R Aguilar, P Pihan, B Henriquez, J Olate, ... Molecular and cellular biology 31 (14), 2997-3008, 2011 | 20 | 2011 |
| Polycomb PRC2 complex mediates epigenetic silencing of a critical osteogenic master regulator in the hippocampus R Aguilar, FJ Bustos, M Saez, A Rojas, ML Allende, AJ van Wijnen, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (8 …, 2016 | 18 | 2016 |
| Wnt/β‐catenin signaling enhances transcription of the CX43 gene in murine Sertoli cells C López, R Aguilar, G Nardocci, K Cereceda, K Vander Stelt, JC Slebe, ... Journal of cellular biochemistry 120 (4), 6753-6762, 2019 | 12 | 2019 |
| Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation HG Lee, S Imaichi, E Kraeutler, R Aguilar, YW Lee, SD Sheridan, JT Lee Cell 186 (12), 2593-2609. e18, 2023 | 11 | 2023 |
| A new nuclear protease with cathepsin L properties is present in HeLa and Caco‐2 cells M Puchi, J García‐Huidobro, C Cordova, R Aguilar, E Dufey, ... Journal of cellular biochemistry 111 (5), 1099-1106, 2010 | 11 | 2010 |
| Downregulation of the Polycomb-Associated Methyltransferase Ezh2 during Maturation of Hippocampal Neurons Is Mediated by MicroRNAs Let-7 and miR-124 L Guajardo, R Aguilar, FJ Bustos, G Nardocci, RA Gutiérrez, ... International Journal of Molecular Sciences 21 (22), 8472, 2020 | 9 | 2020 |
| A Functional N‐terminal Domain in C/EBPβ‐LAP* is Required for Interacting with SWI/SNF and to Repress Ric‐8B Gene Transcription in Osteoblasts R Aguilar, R Grandy, D Meza, H Sepulveda, P Pihan, AJ van Wijnen, ... Journal of cellular physiology 229 (10), 1521-1528, 2014 | 9 | 2014 |
| Epigenetic silencing of the osteoblast‐lineage gene program during hippocampal maturation R Aguilar, FJ Bustos, G Nardocci, B van Zundert, M Montecino Journal of Cellular Biochemistry 122 (3-4), 367-384, 2021 | 6 | 2021 |
Martin MontecinoProfessor and Director, Institute of Biomedical Sciences, Universidad Andres BelloDirección de correo verificada de unab.cl
