Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, ... Science 339 (6116), 211-214, 2013 | 1595 | 2013 |
Histone deacetylase 8 in neuroblastoma tumorigenesis I Oehme, HE Deubzer, D Wegener, D Pickert, JP Linke, B Hero, ... Clinical Cancer Research 15 (1), 91-99, 2009 | 454 | 2009 |
Design and evaluation of ‘Linkerless’ hydroxamic acids as selective HDAC8 inhibitors K KrennHrubec, BL Marshall, M Hedglin, E Verdin, SM Ulrich Bioorganic & medicinal chemistry letters 17 (10), 2874-2878, 2007 | 245 | 2007 |
A quorum-sensing antagonist targets both membrane-bound and cytoplasmic receptors and controls bacterial pathogenicity LR Swem, DL Swem, CT O'Loughlin, R Gatmaitan, B Zhao, SM Ulrich, ... Molecular cell 35 (2), 143-153, 2009 | 243 | 2009 |
Unnatural ligands for engineered proteins: new tools for chemical genetics A Bishop, O Buzko, S Heyeck-Dumas, I Jung, B Kraybill, Y Liu, K Shah, ... Annual review of biophysics and biomolecular structure 29 (1), 577-606, 2000 | 215 | 2000 |
Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells CA Stalnecker, SM Ulrich, Y Li, S Ramachandran, MK McBrayer, ... Proceedings of the National Academy of Sciences 112 (2), 394-399, 2015 | 94 | 2015 |
A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor T Su, DM Bryant, F Luton, M Vergés, SM Ulrich, KC Hansen, A Datta, ... Nature cell biology 12 (12), 1143-1153, 2010 | 84 | 2010 |
Acetylation of heat shock protein 20 (Hsp20) regulates human myometrial activity M Karolczak-Bayatti, M Sweeney, J Cheng, L Edey, SC Robson, ... Journal of Biological Chemistry 286 (39), 34346-34355, 2011 | 70 | 2011 |
Histone deacetylase 8 is deregulated in urothelial cancer but not a target for efficient treatment M Lehmann, MJ Hoffmann, A Koch, SM Ulrich, WA Schulz, G Niegisch Journal of Experimental & Clinical Cancer Research 33, 1-14, 2014 | 40 | 2014 |
Methods of modulating tubulin deacetylase activity EM Verdin, BJ North, SM Ulrich US Patent 7,351,542, 2008 | 40 | 2008 |
Engineering a “methionine clamp” into Src family kinases enhances specificity toward unnatural ATP analogues SM Ulrich, DM Kenski, KM Shokat Biochemistry 42 (26), 7915-7921, 2003 | 32 | 2003 |
Towards the engineering of an orthogonal protein kinase/nucleotide triphosphate pair SM Ulrich, O Buzko, K Shah, KM Shokat Tetrahedron 56 (48), 9495-9502, 2000 | 27 | 2000 |
Small molecule antagonists of bacterial quorum-sensing receptors BL Bassler, LR Swem, SM Ulrich, CT O'loughlin US Patent 8,247,443, 2012 | 15 | 2012 |
Lysine deacetylase inhibition promotes relaxation of arterial tone and C‐terminal acetylation of HSPB6 (Hsp20) in vascular smooth muscle cells A Chen, M Karolczak‐Bayatti, M Sweeney, A Treumann, K Morrissey, ... Physiological reports 1 (6), 2013 | 14 | 2013 |
Conformational restraint is a critical determinant of unnatural nucleotide recognition by protein kinases SM Ulrich, NA Sallee, KM Shokat Bioorganic & medicinal chemistry letters 12 (21), 3223-3227, 2002 | 13 | 2002 |
Ketogenic diet or BHB improves epileptiform spikes, memory, survival in Alzheimer’s model JC Newman, F Kroll, S Ulrich, JJ Palop, E Verdin bioRxiv, 136226, 2017 | 7 | 2017 |
Design, synthesis, and evaluation of transition-state analogs as inhibitors of the bacterial quorum sensing autoinducer synthase CepI EL Higgins, JS Kellner-Rogers, AM Estanislau, AC Esposito, NR Vail, ... Bioorganic & medicinal chemistry letters 39, 127873, 2021 | 5 | 2021 |
synthesis of 3-hydroxybutyryl 3-hydroxybutyrate and related compounds SM Ulrich US Patent App. 15/733,403, 2021 | 3 | 2021 |
Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same E Verdin, SM Ulrich, JC Newman US Patent 10,889,538, 2021 | 3 | 2021 |
Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same E Verdin, SM Ulrich, JC Newman US Patent 10,647,658, 2020 | 3 | 2020 |