| “Function-first” lead discovery: mode of action profiling of natural product libraries using image-based screening CJ Schulze, WM Bray, MH Woerhmann, J Stuart, RS Lokey, RG Linington Chemistry & biology 20 (2), 285-295, 2013 | 107 | 2013 |
| A β-Carboline Alkaloid from the Papua New Guinea Marine Sponge Hyrtios reticulatus WD Inman, WM Bray, NC Gassner, RS Lokey, K Tenney, YY Shen, ... Journal of natural products 73 (2), 255-257, 2009 | 89 | 2009 |
| Natural product libraries to accelerate the high-throughput discovery of therapeutic leads TA Johnson, J Sohn, WD Inman, SA Estee, ST Loveridge, HC Vervoort, ... Journal of natural products 74 (12), 2545-2555, 2011 | 87 | 2011 |
| Reliance of Wolbachia on high rates of host proteolysis revealed by a genome-wide RNAi screen of Drosophila cells PM White, LR Serbus, A Debec, A Codina, W Bray, A Guichet, RS Lokey, ... Genetics, genetics. 116.198903, 2017 | 85 | 2017 |
| Mechanism of action-based classification of antibiotics using high-content bacterial image analysis KC Peach, WM Bray, D Winslow, PF Linington, RG Linington Molecular BioSystems 9 (7), 1837-1848, 2013 | 85 | 2013 |
| Coherence between cellular responses and in vitro splicing inhibition for the anti-tumor drug pladienolide B and its analogs KA Effenberger, DD Anderson, WM Bray, BE Prichard, N Ma, MS Adams, ... Journal of Biological Chemistry 289 (4), 1938-1947, 2014 | 72 | 2014 |
| Image-based 384-well high-throughput screening method for the discovery of skyllamycins A to C as biofilm inhibitors and inducers of biofilm detachment in Pseudomonas aeruginosa G Navarro, AT Cheng, KC Peach, WM Bray, VS Bernan, FH Yildiz, ... Antimicrobial agents and chemotherapy 58 (2), 1092-1099, 2014 | 64 | 2014 |
| A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia LR Serbus, F Landmann, WM Bray, PM White, J Ruybal, RS Lokey, ... PLoS pathogens 8 (9), e1002922, 2012 | 58 | 2012 |
| Large-scale cytological profiling for functional analysis of bioactive compounds MH Woehrmann, WM Bray, JK Durbin, SC Nisam, AK Michael, E Glassey, ... Molecular BioSystems 9 (11), 2604-2617, 2013 | 56 | 2013 |
| An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae KC Peach, WM Bray, NJ Shikuma, NC Gassner, RS Lokey, FH Yildiz, ... Molecular BioSystems 7 (4), 1176-1184, 2011 | 49 | 2011 |
| Genome‐based identification of a plant‐associated marine bacterium as a rich natural product source R Ueoka, A Bhushan, SI Probst, WM Bray, RS Lokey, RG Linington, J Piel Angewandte Chemie International Edition, 2018 | 38 | 2018 |
| An NF-κB-based high-throughput screen identifies piericidins as inhibitors of the Yersinia pseudotuberculosis type III secretion system MC Duncan, WR Wong, AJ Dupzyk, WM Bray, RG Linington, V Auerbuch Antimicrobial agents and chemotherapy 58 (2), 1118-1126, 2014 | 38 | 2014 |
| Biofilm formation and detachment in gram-negative pathogens is modulated by select bile acids LM Sanchez, AT Cheng, CJA Warner, L Townsley, KC Peach, G Navarro, ... PloS one 11 (3), e0149603, 2016 | 36 | 2016 |
| Phenotype-guided natural products discovery using cytological profiling JL Ochoa, WM Bray, RS Lokey, RG Linington Journal of natural products 78 (9), 2242-2248, 2015 | 36 | 2015 |
| A high-throughput splicing assay identifies new classes of inhibitors of human and yeast spliceosomes KA Effenberger, RJ Perriman, WM Bray, RS Lokey, M Ares Jr, MS Jurica Journal of biomolecular screening 18 (9), 1110-1120, 2013 | 36 | 2013 |
| Borrelidin B: isolation, biological activity, and implications for nitrile biosynthesis CJ Schulze, WM Bray, F Loganzo, MH Lam, T Szal, A Villalobos, ... Journal of natural products 77 (11), 2570-2574, 2014 | 35 | 2014 |
| New structures and bioactivity properties of jasplakinolide (jaspamide) analogues from marine sponges SJ Robinson, BI Morinaka, T Amagata, K Tenney, WM Bray, NC Gassner, ... Journal of medicinal chemistry 53 (4), 1651-1661, 2010 | 35 | 2010 |
| Biostructural features of additional jasplakinolide (jaspamide) analogues KR Watts, BI Morinaka, T Amagata, SJ Robinson, K Tenney, WM Bray, ... Journal of natural products 74 (3), 341-351, 2011 | 23 | 2011 |
| Confirmation of the cellular targets of benomyl and rapamycin using next-generation sequencing of resistant mutants in S. cerevisiae DA Wride, N Pourmand, WM Bray, JJ Kosarchuk, SC Nisam, TK Quan, ... Molecular bioSystems 10 (12), 3179-3187, 2014 | 21 | 2014 |
| Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness G Navarro, S Chokpaiboon, G De Muylder, WM Bray, SC Nisam, ... PloS one 7 (9), e46172, 2012 | 16 | 2012 |
