| Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes G de Bruin, EM Huber, BT Xin, EJ van Rooden, K Al-Ayed, KB Kim, ... Journal of medicinal chemistry 57 (14), 6197-6209, 2014 | 120 | 2014 |
| Activity-based protein profiling identifies α-ketoamides as inhibitors for phospholipase A2 group XVI J Zhou, ED Mock, A Martella, V Kantae, X Di, L Burggraaff, MP Baggelaar, ... ACS Chemical Biology 14 (2), 164-169, 2019 | 30 | 2019 |
| Synthetic studies with the brevicidine and laterocidine lipopeptide antibiotics including analogues with enhanced properties and in vivo efficacy K Al Ayed, RD Ballantine, M Hoekstra, SJ Bann, CMJ Wesseling, ... Chemical Science 13 (12), 3563-3570, 2022 | 20 | 2022 |
| Structure–activity relationship studies of α-ketoamides as inhibitors of the phospholipase A and acyltransferase enzyme family J Zhou, ED Mock, K Al Ayed, X Di, V Kantae, L Burggraaff, AF Stevens, ... Journal of Medicinal Chemistry 63 (17), 9340-9359, 2020 | 13 | 2020 |
| Total synthesis and structure assignment of the relacidine lipopeptide antibiotics and preparation of analogues with enhanced stability K Al Ayed, D Zamarbide Losada, NV Machushynets, B Terlouw, ... ACS infectious diseases 9 (4), 739-748, 2023 | 5 | 2023 |
| Synthesis and structure–activity relationship studies of N-terminal analogues of the lipopeptide antibiotics brevicidine and laterocidine RD Ballantine, K Al Ayed, SJ Bann, M Hoekstra, NI Martin, SA Cochrane RSC Medicinal Chemistry 13 (12), 1640-1643, 2022 | 4 | 2022 |
| Linearization of the brevicidine and laterocidine lipopeptides yields analogues that retain full antibacterial activity RD Ballantine, K Al Ayed, SJ Bann, M Hoekstra, NI Martin, SA Cochrane Journal of Medicinal Chemistry 66 (8), 6002-6009, 2023 | 3 | 2023 |
| Discovery and Derivatization of Tridecaptin Antibiotics with Altered Host Specificity and Enhanced Bioactivity NV Machushynets, K Al Ayed, BR Terlouw, C Du, NP Buijs, J Willemse, ... ACS Chemical Biology, 2024 | | 2024 |
Mario van der SteltLeiden UniversityVerified email at chem.leidenuniv.nl
