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Jeffery M. Tharp
Jeffery M. Tharp
Indiana University School of Medicine
Verified email at iu.edu - Homepage
Title
Cited by
Cited by
Year
Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool
W Wan, JM Tharp, WR Liu
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (6), 1059-1070, 2014
4222014
Expanding the chemical diversity of lasso peptide MccJ25 with genetically encoded noncanonical amino acids
FJ Piscotta, JM Tharp, WR Liu, AJ Link
Chemical communications 51 (2), 409-412, 2015
742015
A genetically encoded, phage‐displayed cyclic‐peptide library
XS Wang, PHC Chen, JT Hampton, JM Tharp, CA Reed, SK Das, ...
Angewandte Chemie 131 (44), 16051-16056, 2019
712019
A Genetically Encoded Allysine for the Synthesis of Proteins with Site‐Specific Lysine Dimethylation
ZA Wang, Y Zeng, Y Kurra, X Wang, JM Tharp, EC Vatansever, WW Hsu, ...
Angewandte Chemie 129 (1), 218-222, 2017
552017
Genetic Incorporation of Seven ortho-Substituted Phenylalanine Derivatives
JM Tharp, YS Wang, YJ Lee, Y Yang, WR Liu
ACS chemical biology 9 (4), 884-890, 2014
542014
tRNAPyl: Structure, function, and applications
JM Tharp, A Ehnbom, WR Liu
RNA biology 15 (4-5), 441-452, 2018
492018
Developmental plasticity of thermal tolerances in temperate and subtropical populations of Drosophila melanogaster
BS Cooper, JM Tharp II, II Jernberg, MJ Angilletta Jr
Journal of Thermal Biology 37 (3), 211-216, 2012
472012
Genetic encoding of three distinct noncanonical amino acids using reprogrammed initiator and nonsense codons
JM Tharp, O Vargas-Rodriguez, A Schepartz, D Soll
ACS chemical biology 16 (4), 766-774, 2021
422021
Initiation of protein synthesis with non‐canonical amino acids in vivo
JM Tharp, O Ad, K Amikura, FR Ward, EM Garcia, JHD Cate, A Schepartz, ...
Angewandte Chemie International Edition 59 (8), 3122-3126, 2020
412020
An amber obligate active site-directed ligand evolution technique for phage display
JM Tharp, JT Hampton, CA Reed, A Ehnbom, PHC Chen, JS Morse, ...
Nature communications 11 (1), 1392, 2020
282020
Genetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader
YJ Lee, MJ Schmidt, JM Tharp, A Weber, AL Koenig, H Zheng, J Gao, ...
Chemical communications 52 (85), 12606-12609, 2016
272016
Hijacking translation initiation for synthetic biology
JM Tharp, N Krahn, U Varshney, D Söll
ChemBioChem 21 (10), 1387-1396, 2020
202020
Engineering aminoacyl-tRNA synthetases for use in synthetic biology
N Krahn, JM Tharp, A Crnković, D Söll
The Enzymes 48, 351-395, 2020
202020
Directed Evolution of Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase Generates a Hyperactive and Highly Selective Variant
JT Fischer, D Söll, JM Tharp
Frontiers in molecular biosciences 9, 850613, 2022
172022
Ancestral archaea expanded the genetic code with pyrrolysine
LT Guo, K Amikura, HK Jiang, T Mukai, X Fu, YS Wang, P O’Donoghue, ...
Journal of Biological Chemistry 298 (11), 2022
122022
Novel regioselective approach to cyclize phage-displayed peptides in combination with epitope-directed selection to identify a potent neutralizing macrocyclic peptide for SARS …
JT Hampton, TJ Lalonde, JM Tharp, Y Kurra, YR Alugubelli, CM Roundy, ...
ACS chemical biology 17 (10), 2911-2922, 2022
72022
Using amber and ochre nonsense codons to code two different noncanonical amino acids in one protein gene
JM Tharp, WR Liu
Noncanonical Amino Acids: Methods and Protocols, 147-154, 2018
72018
Initiating protein synthesis with noncanonical monomers in vitro and in vivo
JM Tharp, JA Walker, D Söll, A Schepartz
Methods in enzymology 656, 495-519, 2021
62021
The “Π-Clamp” Offers a Novel Strategy for Site-Selective Protein Modification
JM Tharp, WR Liu
Chembiochem: a European journal of chemical biology 17 (10), 883, 2016
62016
Synthetases pick up the pace
JM Tharp, WR Liu
Nature Chemical Biology 13 (12), 1205-1206, 2017
32017
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