| Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature‐tagged transposon mutagenesis LR Camacho, D Ensergueix, E Perez, B Gicquel, C Guilhot Molecular microbiology 34 (2), 257-267, 1999 | 790 | 1999 |
| An essential role for phoP in Mycobacterium tuberculosis virulence E Pérez, S Samper, Y Bordas, C Guilhot, B Gicquel, C Martín Molecular microbiology 41 (1), 179-187, 2001 | 478 | 2001 |
| Fueling open‐source drug discovery: 177 small‐molecule leads against tuberculosis L Ballell, RH Bates, RJ Young, D Alvarez‐Gomez, E Alvarez‐Ruiz, ... ChemMedChem 8 (2), 313-321, 2013 | 357 | 2013 |
| Role of the pks15/1 Gene in the Biosynthesis of Phenolglycolipids in the Mycobacterium tuberculosisComplex: EVIDENCE THAT ALL STRAINS SYNTHESIZE GLYCOSYLATEDp-HYDROXYBENZOIC … P Constant, E Perez, W Malaga, MA Lanéelle, O Saurel, M Daffé, ... Journal of Biological Chemistry 277 (41), 38148-38158, 2002 | 301 | 2002 |
| IS6110 Mediates Increased Transcription of the phoP Virulence Gene in a Multidrug-Resistant Clinical Isolate Responsible for Tuberculosis Outbreaks CY Soto, MC Menéndez, E Pérez, S Samper, AB Gómez, MJ García, ... Journal of clinical microbiology 42 (1), 212-219, 2004 | 158 | 2004 |
| Tetrahydropyrazolo [1, 5-a] pyrimidine-3-carboxamide and N-benzyl-6′, 7′-dihydrospiro [piperidine-4, 4′-thieno [3, 2-c] pyran] analogues with bactericidal efficacy against … MJ Remuiñán, E Pérez-Herrán, J Rullás, C Alemparte, M Martínez-Hoyos, ... PloS one 8 (4), e60933, 2013 | 152 | 2013 |
| Aminoglycoside 2′‐N‐acetyltransferase genes are universally present in mycobacteria: characterization of the aac (2′)‐Ic gene from Mycobacterium tuberculosis and the aac (2 … JA Aínsa, E Pérez, V Pelicic, FX Berthet, B Gicquel, C Martín Molecular microbiology 24 (2), 431-441, 1997 | 143 | 1997 |
| Discovery of a potent and specific M. tuberculosis Leucyl-tRNA synthetase inhibitor:(S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy) benzo [c][1, 2] oxaborol-1 (3 H)-ol (GSK656) X Li, V Hernandez, FL Rock, W Choi, YSL Mak, M Mohan, W Mao, Y Zhou, ... Journal of medicinal chemistry 60 (19), 8011-8026, 2017 | 141 | 2017 |
| Evidence for a partial redundancy of the fibronectin‐binding proteins for the transfer of mycoloyl residues onto the cell wall arabinogalactan termini of Mycobacterium tuberculosis V Puech, C Guilhot, E Perez, M Tropis, LY Armitige, B Gicquel, M Daffé Molecular microbiology 44 (4), 1109-1122, 2002 | 130 | 2002 |
| Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium … L Encinas, H O’Keefe, M Neu, MJ Remuiñán, AM Patel, A Guardia, ... Journal of Medicinal Chemistry 57 (4), 1276-1288, 2014 | 121 | 2014 |
| Discovery of novel oral protein synthesis inhibitors of Mycobacterium tuberculosis that target leucyl-tRNA synthetase A Palencia, X Li, W Bu, W Choi, CZ Ding, EE Easom, L Feng, ... Antimicrobial agents and chemotherapy 60 (10), 6271-6280, 2016 | 109 | 2016 |
| Inhibiting the stringent response blocks Mycobacterium tuberculosis entry into quiescence and reduces persistence NK Dutta, LG Klinkenberg, MJ Vazquez, D Segura-Carro, G Colmenarejo, ... Science Advances 5 (3), eaav2104, 2019 | 103 | 2019 |
| Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry. E Hunsche, T Krieg, B Schwierin, D Rosenberg, B Raffier, M Hirschi, ... Clinical and experimental rheumatology 31 (2 Suppl 76), 71-80, 2013 | 98 | 2013 |
| Characterization of three glycosyltransferases involved in the biosynthesis of the phenolic glycolipid antigens from the Mycobacterium tuberculosis complex E Pérez, P Constant, A Lemassu, F Laval, M Daffé, C Guilhot Journal of Biological Chemistry 279 (41), 42574-42583, 2004 | 91 | 2004 |
| Development of an intracellular screen for new compounds able to inhibit Mycobacterium tuberculosis growth in human macrophages F Sorrentino, R Gonzalez del Rio, X Zheng, J Presa Matilla, ... Antimicrobial agents and chemotherapy 60 (1), 640-645, 2016 | 79 | 2016 |
| Mycobacterium leprae Phenolglycolipid-1 Expressed by Engineered M. bovis BCG Modulates Early Interaction with Human Phagocytes G Tabouret, C Astarie-Dequeker, C Demangel, W Malaga, P Constant, ... PLoS pathogens 6 (10), e1001159, 2010 | 75 | 2010 |
| Molecular dissection of the role of two methyltransferases in the biosynthesis of phenolglycolipids and phthiocerol dimycoserosate in the Mycobacterium tuberculosis complex E Pérez, P Constant, F Laval, A Lemassu, MA Lanéelle, M Daffé, ... Journal of Biological Chemistry 279 (41), 42584-42592, 2004 | 75 | 2004 |
| Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor M Martínez-Hoyos, E Perez-Herran, G Gulten, L Encinas, ... EBioMedicine 8, 291-301, 2016 | 66 | 2016 |
| Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase SM Batt, M Cacho Izquierdo, J Castro Pichel, CJ Stubbs, ... ACS Infectious Diseases 1 (12), 615-626, 2015 | 65 | 2015 |
| Live tuberculosis vaccines based on phoP mutants: a step towards clinical trials JAG Asensio, A Arbués, E Pérez, B Gicquel, C Martin Expert opinion on biological therapy 8 (2), 201-211, 2008 | 61 | 2008 |
