| Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa MK Sarkar, GA Hile, LC Tsoi, X Xing, J Liu, Y Liang, CC Berthier, ... Annals of the rheumatic diseases 77 (11), 1653-1664, 2018 | 204 | 2018 |
| Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies N Altorok, PS Tsou, P Coit, D Khanna, AH Sawalha Annals of the rheumatic diseases 74 (8), 1612-1620, 2015 | 179 | 2015 |
| Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor–regulated gene transcription prevent fibrosis in a murine … AJ Haak, PS Tsou, MA Amin, JH Ruth, P Campbell, DA Fox, D Khanna, ... Journal of Pharmacology and Experimental Therapeutics 349 (3), 480-486, 2014 | 108 | 2014 |
| Dysregulated expression of MIG/CXCL9, IP-10/CXCL10 and CXCL16 and their receptors in systemic sclerosis BJ Rabquer, PS Tsou, Y Hou, E Thirunavukkarasu, GK Haines, AJ Impens, ... Arthritis research & therapy 13, 1-10, 2011 | 97 | 2011 |
| Unfolding the pathogenesis of scleroderma through genomics and epigenomics PS Tsou, AH Sawalha Journal of autoimmunity 83, 73-94, 2017 | 93 | 2017 |
| Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription PS Tsou, AJ Haak, D Khanna, RR Neubig American Journal of Physiology-Cell Physiology 307 (1), C2-C13, 2014 | 87 | 2014 |
| Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma PS Tsou, P Campbell, MA Amin, P Coit, S Miller, DA Fox, D Khanna, ... Proceedings of the National Academy of Sciences 116 (9), 3695-3702, 2019 | 85 | 2019 |
| Junctional adhesion molecule-C is a soluble mediator of angiogenesis BJ Rabquer, MA Amin, N Teegala, MK Shaheen, PS Tsou, JH Ruth, ... The Journal of Immunology 185 (3), 1777-1785, 2010 | 83 | 2010 |
| Histone deacetylase 5 is overexpressed in scleroderma endothelial cells and impairs angiogenesis via repression of proangiogenic factors PS Tsou, JD Wren, MA Amin, E Schiopu, DA Fox, D Khanna, AH Sawalha Arthritis & Rheumatology 68 (12), 2975-2985, 2016 | 65 | 2016 |
| Advances in epigenetics in systemic sclerosis: molecular mechanisms and therapeutic potential PS Tsou, J Varga, S O’Reilly Nature Reviews Rheumatology 17 (10), 596-607, 2021 | 57 | 2021 |
| A unique role for galectin-9 in angiogenesis and inflammatory arthritis MJ O’Brien, Q Shu, WA Stinson, PS Tsou, JH Ruth, T Isozaki, ... Arthritis Research & Therapy 20, 1-8, 2018 | 55 | 2018 |
| EZH2 modulates the DNA methylome and controls T cell adhesion through junctional adhesion molecule A in lupus patients PS Tsou, P Coit, NC Kilian, AH Sawalha Arthritis & rheumatology 70 (1), 98-108, 2018 | 53 | 2018 |
| Scleroderma keratinocytes promote fibroblast activation independent of transforming growth factor beta SS McCoy, TJ Reed, CC Berthier, PS Tsou, J Liu, JE Gudjonsson, ... Rheumatology 56 (11), 1970-1981, 2017 | 53 | 2017 |
| Inhibition of EZH2 Ameliorates Lupus‐Like Disease in MRL/lpr Mice DM Rohraff, Y He, EA Farkash, M Schonfeld, PS Tsou, AH Sawalha Arthritis & Rheumatology 71 (10), 1681-1690, 2019 | 50 | 2019 |
| Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma KM Hutchings, EM Lisabeth, W Rajeswaran, MW Wilson, RJ Sorenson, ... Bioorganic & medicinal chemistry letters 27 (8), 1744-1749, 2017 | 48 | 2017 |
| Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts PS Tsou, NN Talia, AJ Pinney, A Kendzicky, S Piera‐Velazquez, ... Arthritis & Rheumatism 64 (6), 1978-1989, 2012 | 48 | 2012 |
| Methyl-CpG-binding protein 2 mediates antifibrotic effects in scleroderma fibroblasts Y He, PS Tsou, D Khanna, AH Sawalha Annals of the rheumatic diseases 77 (8), 1208-1218, 2018 | 44 | 2018 |
| 5-Aryl-1, 3, 4-oxadiazol-2-ylthioalkanoic acids: a highly potent new class of inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF … DJ Kahl, KM Hutchings, EM Lisabeth, AJ Haak, JR Leipprandt, ... Journal of medicinal chemistry 62 (9), 4350-4369, 2019 | 37 | 2019 |
| Fucosyltransferase 1 mediates angiogenesis, cell adhesion and rheumatoid arthritis synovial tissue fibroblast proliferation T Isozaki, JH Ruth, MA Amin, PL Campbell, PS Tsou, CM Ha, GK Haines, ... Arthritis research & therapy 16, 1-14, 2014 | 37 | 2014 |
| Caffeine inhibits STAT1 signaling and downregulates inflammatory pathways involved in autoimmunity M Iris, PS Tsou, AH Sawalha Clinical Immunology 192, 68-77, 2018 | 36 | 2018 |
