| Organotypic 3D cell culture models: using the rotating wall vessel to study host–pathogen interactions J Barrila, AL Radtke, A Crabbé, SF Sarker, MM Herbst-Kralovetz, CM Ott, ... Nature Reviews Microbiology 8 (11), 791-801, 2010 | 326 | 2010 |
| Identification of Novel Inhibitors of the SARS Coronavirus Main Protease 3CLpro U Bacha, J Barrila, A Velazquez-Campoy, SA Leavitt, E Freire Biochemistry 43 (17), 4906-4912, 2004 | 267 | 2004 |
| Media ion composition controls regulatory and virulence response of Salmonella in spaceflight JW Wilson, CM Ott, L Quick, R Davis, KH zu Bentrup, A Crabbé, E Richter, ... PloS one 3 (12), e3923, 2008 | 189 | 2008 |
| Modeling host-pathogen interactions in the context of the microenvironment: three-dimensional cell culture comes of age J Barrila, A Crabbé, J Yang, K Franco, SD Nydam, RJ Forsyth, RR Davis, ... Infection and immunity 86 (11), 10.1128/iai. 00282-18, 2018 | 143 | 2018 |
| Spaceflight Enhances Cell Aggregation and Random Budding in Candida albicans A Crabbé, SM Nielsen-Preiss, CM Woolley, J Barrila, K Buchanan, ... PloS one 8 (12), e80677, 2013 | 97 | 2013 |
| Structure and activity of the axon guidance protein MICAL M Nadella, MA Bianchet, SB Gabelli, J Barrila, LM Amzel Proceedings of the National Academy of Sciences 102 (46), 16830-16835, 2005 | 94 | 2005 |
| Long-Range Cooperative Interactions Modulate Dimerization in SARS 3CLpro J Barrila, U Bacha, E Freire Biochemistry 45 (50), 14908-14916, 2006 | 91 | 2006 |
| Analysis of glycolytic enzyme co-localization in Drosophilaflight muscle DT Sullivan, R MacIntyre, N Fuda, J Fiori, J Barrilla, L Ramizel Journal of Experimental Biology 206 (12), 2031-2038, 2003 | 89 | 2003 |
| Recellularization of decellularized lung scaffolds is enhanced by dynamic suspension culture A Crabbé, Y Liu, SF Sarker, NR Bonenfant, J Barrila, ZD Borg, JJ Lee, ... PloS one 10 (5), e0126846, 2015 | 69 | 2015 |
| Development of Broad‐Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLpro U Bacha, J Barrila, SB Gabelli, Y Kiso, L Mario Amzel, E Freire Chemical biology & drug design 72 (1), 34-49, 2008 | 61 | 2008 |
| Synthesis of glutamic acid and glutamine peptides possessing a trifluoromethyl ketone group as SARS-CoV 3CL protease inhibitors MO Sydnes, Y Hayashi, VK Sharma, T Hamada, U Bacha, J Barrila, ... Tetrahedron 62 (36), 8601-8609, 2006 | 60 | 2006 |
| Mutation of Asn28 Disrupts the Dimerization and Enzymatic Activity of SARS 3CLpro, J Barrila, SB Gabelli, U Bacha, LM Amzel, E Freire Biochemistry 49 (20), 4308-4317, 2010 | 56 | 2010 |
| Characterization of the Invasive, Multidrug Resistant Non-typhoidal Salmonella Strain D23580 in a Murine Model of Infection J Yang, J Barrila, KL Roland, J Kilbourne, CM Ott, RJ Forsyth, ... PLoS Neglected Tropical Diseases 9 (6), e0003839, 2015 | 47 | 2015 |
| Three-dimensional organotypic co-culture model of intestinal epithelial cells and macrophages to study Salmonella enterica colonization patterns J Barrila, J Yang, A Crabbé, SF Sarker, Y Liu, CM Ott, ... npj Microgravity 3 (1), 10, 2017 | 41 | 2017 |
| Spaceflight modulates gene expression in the whole blood of astronauts J Barrila, CM Ott, C LeBlanc, SK Mehta, A Crabbé, P Stafford, DL Pierson, ... npj Microgravity 2 (1), 1-3, 2016 | 37 | 2016 |
| Evaluation of microorganisms cultured from injured and repressed tissue regeneration sites in endangered giant aquatic Ozark hellbender salamanders CA Nickerson, CM Ott, SL Castro, VM Garcia, TC Molina, JT Briggler, ... PLoS one 6 (12), e28906, 2011 | 32 | 2011 |
| Microbial stress: spaceflight-induced alterations in microbial virulence and infectious disease risks for the crew CM Ott, A Crabbé, JW Wilson, J Barrila, SL Castro-Wallace, CA Nickerson Stress Challenges and Immunity in Space: From Mechanisms to Monitoring and …, 2020 | 26 | 2020 |
| Physiological fluid shear alters the virulence potential of invasive multidrug-resistant non-typhoidal Salmonella Typhimurium D23580 J Yang, J Barrila, KL Roland, CM Ott, CA Nickerson npj Microgravity 2 (1), 1-3, 2016 | 26 | 2016 |
| Evaluating the effect of spaceflight on the host–pathogen interaction between human intestinal epithelial cells and Salmonella Typhimurium J Barrila, SF Sarker, N Hansmeier, S Yang, K Buss, N Briones, J Park, ... npj Microgravity 7 (1), 9, 2021 | 20 | 2021 |
| Longitudinal characterization of multispecies microbial populations recovered from spaceflight potable water J Yang, J Barrila, C Mark Ott, O King, R Bruce, RJC McLean, ... npj Biofilms and Microbiomes 7 (1), 70, 2021 | 15 | 2021 |
