| Receptor-mediated entry of pristine octahedral DNA nanocages in mammalian cells G Vindigni, S Raniolo, A Ottaviani, M Falconi, O Franch, BR Knudsen, ... ACS nano 10 (6), 5971-5979, 2016 | 87 | 2016 |
| Selective targeting and degradation of doxorubicin-loaded folate-functionalized DNA nanocages S Raniolo, G Vindigni, A Ottaviani, V Unida, F Iacovelli, A Manetto, ... Nanomedicine: Nanotechnology, Biology and Medicine 14 (4), 1181-1190, 2018 | 71 | 2018 |
| In vitro elimination of epidermal growth factor receptor‐overexpressing cancer cells by CD32A‐chimeric receptor T cells in combination with cetuximab or … S Caratelli, R Arriga, T Sconocchia, A Ottaviani, G Lanzilli, D Pastore, ... International journal of cancer 146 (1), 236-247, 2020 | 35 | 2020 |
| Entry, fate and degradation of DNA nanocages in mammalian cells: a matter of receptors S Raniolo, G Vindigni, V Unida, A Ottaviani, E Romano, A Desideri, ... Nanoscale 10 (25), 12078-12086, 2018 | 35 | 2018 |
| Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico C Tesauro, B Morozzo della Rocca, A Ottaviani, A Coletta, L Zuccaro, ... Molecular cancer 12, 1-13, 2013 | 34 | 2013 |
| DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family O Franch, F Iacovelli, M Falconi, S Juul, A Ottaviani, C Benvenuti, ... Nanoscale 8 (27), 13333-13341, 2016 | 28 | 2016 |
| Recent perspective on CAR and Fcγ-CR T cell immunotherapy for cancers: Preclinical evidence versus clinical outcomes HE Marei, A Althani, T Caceci, R Arriga, T Sconocchia, A Ottaviani, ... Biochemical Pharmacology 166, 335-346, 2019 | 25 | 2019 |
| Simulative and experimental characterization of a pH-Dependent Clamp-like DNA Triple-Helix nanoswitch F Iacovelli, A Idili, A Benincasa, D Mariottini, A Ottaviani, M Falconi, ... Journal of the American Chemical Society 139 (15), 5321-5329, 2017 | 22 | 2017 |
| Topoisomerase IB: a relaxing enzyme for stressed DNA BC Soren, JB Dasari, A Ottaviani, F Iacovelli, P Fiorani Cancer Drug Resistance 3 (1), 18, 2020 | 21 | 2020 |
| Cow Milk extracellular vesicle effects on an In vitro model of intestinal inflammation S Mecocci, A Ottaviani, E Razzuoli, P Fiorani, D Pietrucci, CG De Ciucis, ... Biomedicines 10 (3), 570, 2022 | 20 | 2022 |
| CD16‐158‐valine chimeric receptor T cells overcome the resistance of KRAS‐mutated colorectal carcinoma cells to cetuximab R Arriga, S Caratelli, G Lanzilli, A Ottaviani, C Cenciarelli, T Sconocchia, ... International journal of cancer 146 (9), 2531-2538, 2020 | 18 | 2020 |
| Engineering a responsive DNA triple helix into an octahedral DNA nanostructure for a reversible opening/closing switching mechanism: a computational and experimental integrated … A Ottaviani, F Iacovelli, A Idili, M Falconi, F Ricci, A Desideri Nucleic acids research 46 (19), 9951-9959, 2018 | 16 | 2018 |
| Natural compounds as therapeutic agents: The case of human topoisomerase ib A Ottaviani, F Iacovelli, P Fiorani, A Desideri International Journal of Molecular Sciences 22 (8), 4138, 2021 | 15 | 2021 |
| Quantum dot based DNA nanosensors for amplification-free detection of human topoisomerase I ML Jepsen, A Ottaviani, BR Knudsen, YP Ho RSC Advances 4 (5), 2491-2494, 2014 | 15 | 2014 |
| Replacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistant B Arnò, I D’Annessa, C Tesauro, L Zuccaro, A Ottaviani, B Knudsen, ... PLoS One 8 (7), e68404, 2013 | 15 | 2013 |
| Imbibition of femtoliter-scale DNA-rich aqueous droplets into porous nylon substrates by molecular printing G Arrabito, V Ferrara, A Ottaviani, F Cavaleri, S Cubisino, P Cancemi, ... Langmuir 35 (52), 17156-17165, 2019 | 13 | 2019 |
| Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation Z Wang, I D'Annessa, C Tesauro, S Croce, A Ottaviani, P Fiorani, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (8), 860-868, 2015 | 13 | 2015 |
| Rolling circle amplification-based detection of human topoisomerase I activity on magnetic beads L Zuccaro, C Tesauro, B Cerroni, A Ottaviani, BR Knudsen, ... Analytical biochemistry 451, 42-44, 2014 | 10 | 2014 |
| Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies S Manni, F Del Bufalo, P Merli, DA Silvestris, M Guercio, S Caruso, ... Nature Communications 14 (1), 3423, 2023 | 8 | 2023 |
| From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica A Ottaviani, J Welsch, K Agama, Y Pommier, A Desideri, BJ Baker, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1404-1410, 2022 | 6 | 2022 |
