| NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis C Marchetti, B Swartzwelter, MI Koenders, T Azam, IW Tengesdal, ... Arthritis research & therapy 20, 1-11, 2018 | 134 | 2018 |
| Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion IW Tengesdal, DR Menon, DG Osborne, CP Neff, NE Powers, F Gamboni, ... Proceedings of the National Academy of Sciences 118 (10), e2000915118, 2021 | 108 | 2021 |
| Biology of IL‐38 and its role in disease FL van de Veerdonk, DM de Graaf, LAB Joosten, CA Dinarello Immunological reviews 281 (1), 191-196, 2018 | 94 | 2018 |
| IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease JF Højen, MLV Kristensen, AS McKee, MT Wade, T Azam, LP Lunding, ... Nature immunology 20 (9), 1138-1149, 2019 | 64 | 2019 |
| Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects DM de Graaf, M Jaeger, ICL van den Munckhof, R Ter Horst, K Schraa, ... European journal of immunology 51 (3), 662-671, 2021 | 29 | 2021 |
| PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis NE Powers, B Swartzwelter, C Marchetti, DM de Graaf, A Lerchner, ... Journal of Biological Chemistry 295 (3), 868-882, 2020 | 27 | 2020 |
| IL‐38 prevents induction of trained immunity by inhibition of mTOR signaling DM de Graaf, LU Teufel, FL van de Veerdonk, LAB Joosten, MG Netea, ... Journal of leukocyte biology 110 (5), 907-915, 2021 | 22 | 2021 |
| Mitochondrial damage activates the NLRP10 inflammasome T Próchnicki, MB Vasconcelos, KS Robinson, MSJ Mangan, D De Graaf, ... Nature Immunology 24 (4), 595-603, 2023 | 21 | 2023 |
| Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease DM de Graaf, RJA Maas, SP Smeekens, E Eisenmesser, JS Redzic, ... Cytokine 137, 155334, 2021 | 20 | 2021 |
| Interleukin-38 in health and disease DM de Graaf, LU Teufel, LAB Joosten, CA Dinarello Cytokine 152, 155824, 2022 | 17 | 2022 |
| A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling S Li, L Jiang, K Beckmann, JF Højen, U Pessara, NE Powers, ... Journal of Biological Chemistry 296, 2021 | 13 | 2021 |
| IL-38 gene deletion worsens murine colitis DM de Graaf, RX Wang, J Amo-Aparicio, JS Lee, AS Dowdell, ... Frontiers in Immunology 13, 840719, 2022 | 11 | 2022 |
| Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3 E The, DM de Graaf, Y Zhai, Q Yao, L Ao, DA Fullerton, CA Dinarello, ... Proceedings of the National Academy of Sciences 119 (36), e2202577119, 2022 | 9 | 2022 |
| Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration YJE Sloot, K Rabold, T Ulas, DM De Graaf, B Heinhuis, K Händler, ... Cellular Oncology 42, 691-703, 2019 | 9 | 2019 |
| Alpha-1 antitrypsin governs alcohol-related liver disease in mice and humans C Grander, B Schaefer, J Schwärzler, F Grabherr, DM de Graaf, B Enrich, ... Gut 70 (3), 585-594, 2021 | 5 | 2021 |
| Aberrant inflammasome activation as a driving force of human autoimmune skin disease T Fetter, DM de Graaf, I Claus, J Wenzel Frontiers in Immunology 14, 1190388, 2023 | 3 | 2023 |
| Circulating interleukin-38 concentrations in healthy adults LU Teufel, DM de Graaf, MG Netea, CA Dinarello, LAB Joosten, RJW Arts Frontiers in Immunology 13, 964365, 2022 | 3 | 2022 |
| Exploratory analysis of interleukin‐38 in hospitalized COVID‐19 patients DM de Graaf, LU Teufel, AH de Nooijer, AJ van Gammeren, AAM Ermens, ... Immunity, Inflammation and Disease 10 (11), e712, 2022 | 1 | 2022 |
| International nomenclature guidelines for the IL-1 family of cytokines and receptors JM Gaballa, JF Højen, DM De Graaf, J Amo-Aparicio, C Marchetti, ... Nature Immunology, 1-2, 2024 | | 2024 |
| IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1β secretion A Dinarello, M May, J Amo-Aparicio, T Azam, JM Gaballa, C Marchetti, ... Proceedings of the National Academy of Sciences 120 (45), e2306476120, 2023 | | 2023 |
