The Nlrp3 inflammasome suppresses colorectal cancer metastatic growth in the liver by promoting natural killer cell tumoricidal activity J Dupaul-Chicoine, A Arabzadeh, M Dagenais, T Douglas, C Champagne, ... Immunity 43 (4), 751-763, 2015 | 305 | 2015 |
Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival IG Rodrigue-Gervais, K Labbé, M Dagenais, J Dupaul-Chicoine, ... Cell host & microbe 15 (1), 23-35, 2014 | 177 | 2014 |
Adenovirus E4 open reading frame 4–induced apoptosis involves dysregulation of Src family kinases JN Lavoie, C Champagne, MC Gingras, A Robert The Journal of Cell Biology 150 (5), 1037-1056, 2000 | 107 | 2000 |
Distinct cell death pathways triggered by the adenovirus early region 4 ORF 4 protein A Robert, MJ Miron, C Champagne, MC Gingras, PE Branton, JN Lavoie The Journal of cell biology 158 (3), 519-528, 2002 | 85 | 2002 |
The inflammatory caspases-1 and-11 mediate the pathogenesis of dermatitis in sharpin-deficient mice T Douglas, C Champagne, A Morizot, JM Lapointe, M Saleh The Journal of Immunology 195 (5), 2365-2373, 2015 | 66 | 2015 |
Activation of adenovirus type 2 early region 4 ORF4 cytoplasmic death function by direct binding to Src kinase domain C Champagne, MC Landry, MC Gingras, JN Lavoie Journal of Biological Chemistry 279 (24), 25905-25915, 2004 | 66 | 2004 |
Cytoplasmic death signal triggered by SRC-mediated phosphorylation of the adenovirus E4orf4 protein MC Gingras, C Champagne, M Roy, JN Lavoie Molecular and cellular biology 22 (1), 41-56, 2002 | 62 | 2002 |
Adenovirus E4orf4 hijacks rho GTPase-dependent actin dynamics to kill cells: a role for endosome-associated actin assembly A Robert, N Smadja-Lamère, MC Landry, C Champagne, R Petrie, ... Molecular biology of the cell 17 (7), 3329-3344, 2006 | 52 | 2006 |
The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis M Dagenais, J Dupaul-Chicoine, T Douglas, C Champagne, A Morizot, ... Oncoimmunology 6 (3), e1287247, 2017 | 51 | 2017 |
Regulation of cell death by recycling endosomes and golgi membrane dynamics via a pathway involving Src-family kinases, Cdc42 and Rab11a MC Landry, A Sicotte, C Champagne, JN Lavoie Molecular biology of the cell 20 (18), 4091-4106, 2009 | 35 | 2009 |
A functional interplay between the small GTPase Rab11a and mitochondria-shaping proteins regulates mitochondrial positioning and polarization of the actin cytoskeleton … MC Landry, C Champagne, MC Boulanger, A Jetté, M Fuchs, ... Journal of Biological Chemistry 289 (4), 2230-2249, 2014 | 33 | 2014 |
JNK-mediated phosphorylation of paxillin in adhesion assembly and tension-induced cell death by the adenovirus death factor E4orf4 N Smadja-Lamere, MC Boulanger, C Champagne, PE Branton, JN Lavoie Journal of biological chemistry 283 (49), 34352-34364, 2008 | 28 | 2008 |
A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways M Dagenais, J Dupaul-Chicoine, C Champagne, A Skeldon, A Morizot, ... Mucosal immunology 9 (1), 146-158, 2016 | 25 | 2016 |
Src-family kinase signaling, actin-mediated membrane trafficking and organellar dynamics in the control of cell fate: lessons to be learned from the adenovirus E4orf4 death factor JN Lavoie, MC Landry, RL Faure, C Champagne Cellular signalling 22 (11), 1604-1614, 2010 | 25 | 2010 |
The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes IG Rodrigue-Gervais, K Doiron, C Champagne, L Mayes, GA Leiva-Torres, ... Scientific reports 8 (1), 8446, 2018 | 21 | 2018 |
Estrogen-related receptor alpha (ERRα) is a key regulator of intestinal homeostasis and protects against colitis A Tran, C Scholtes, M Songane, C Champagne, L Galarneau, ... Scientific reports 11 (1), 15073, 2021 | 15 | 2021 |
Rôle du transport endosomal dépendant du rétromère dans la formation des podosomes en réponse à l'activation de V-SRC A Damlaj, MC Boulanger, C Champagne, JN Lavoie Université Laval, 2012 | 1 | 2012 |
Human NLRC4 promotes cancer survival and is associated to type-I interferon signaling and immune infiltration C Domblides, S Crampton, H Liu, JM Bartleson, A Nguyen, C Champagne, ... The Journal of Clinical Investigation, 2024 | | 2024 |
Cross-regulation between the inflammasome and linear ubiquitination machinery T Douglas, C Champagne, JM Lapointe, M Saleh EUROPEAN JOURNAL OF IMMUNOLOGY 46, 1086-1086, 2016 | | 2016 |
Focal Adhesions and Actin Remodeling by the JNK MAP Kinase Pathway: A Role in Adenovirus E4orf4-dependent Cell Killing N Smadja-Lamere, D Allard, C Champagne, JN Lavoie MOLECULAR BIOLOGY OF THE CELL 17, 2006 | | 2006 |