Physiologically based pharmacokinetics modeling and transporter proteomics to predict systemic and local liver and muscle disposition of statins. A Vildhede, P Nordell, C Ahlström, AB Montaser, T Terasaki, H Lennernäs, ... CPT: Pharmacometrics & Systems Pharmacology, 2024 | | 2024 |
Quantitative imaging of doxorubicin diffusion and cellular uptake in biomimetic gels with human liver tumor cells O Degerstedt, P O’Callaghan, AL Clavero, J Gråsjö, O Eriksson, ... Drug Delivery and Translational Research 14 (4), 970-983, 2024 | | 2024 |
Physiologically based pharmacokinetics modeling and transporter proteomics to predict systemic and local liver and muscle disposition of statins L Prieto Garcia, A Vildhede, P Nordell, C Ahlström, AB Montaser, ... CPT: Pharmacometrics & Systems Pharmacology, 2024 | | 2024 |
Understanding Statin‐Roxadustat Drug–Drug‐Disease Interaction Using Physiologically‐Based Pharmacokinetic Modeling J Dong, L Prieto Garcia, Y Huang, W Tang, A Lundahl, M Elebring, ... Clinical Pharmacology & Therapeutics 114 (4), 825-835, 2023 | 4 | 2023 |
Physiologically based pharmacokinetic modelling of rilpivirine and lenacapavir delivery by microarray patches for treatment of pediatric HIV infection RKM Choy, J Mistilis, L Vora, FV Zanutto, AHB Sabri, I Tekko, K Moffatt, ... 7th International Conference on Microneedles 2023, 2023 | | 2023 |
Physiologically based biopharmaceutics modeling of regional and colon absorption in humans C Tannergren, H Jadhav, E Eckernäs, J Fagerberg, P Augustijns, ... European Journal of Pharmaceutics and Biopharmaceutics 186, 144-159, 2023 | 5 | 2023 |
Integrated Physiologically-Based Pharmacokinetic Model with a Quantitative Systems Pharmacology and Toxicology Model for Statins in Disease Population LP Garcia, P Nordell, C Ahlström, H Lennernäs, E Sjögren | | 2023 |
Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection … SS Nyman, H Ahlström, AD Creusen, D Dahlgren, M Hedeland, ... BMJ open 12 (11), e065839, 2022 | 2 | 2022 |
Does the choice of applied physiologically‐based pharmacokinetics platform matter? A case study on simvastatin disposition and drug–drug interaction L Prieto Garcia, A Lundahl, C Ahlström, A Vildhede, H Lennernäs, ... CPT: Pharmacometrics & Systems Pharmacology 11 (9), 1194-1209, 2022 | 6 | 2022 |
Physiological based pharmacokinetic and biopharmaceutics modelling of subcutaneously administered compounds–An overview of in silico models IR Dubbelboer, E Sjögren International journal of pharmaceutics 621, 121808, 2022 | 9 | 2022 |
Overview of authorized drug products for subcutaneous administration: pharmaceutical, therapeutic, and physicochemical properties IR Dubbelboer, E Sjögren European Journal of Pharmaceutical Sciences 173, 106181, 2022 | 1 | 2022 |
Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue O Degerstedt, J Gråsjö, A Norberg, E Sjögren, P Hansson, H Lennernäs European Journal of Pharmaceutical Sciences 172, 106150, 2022 | 5 | 2022 |
Protocol: Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose … SS Nyman, H Ahlström, AD Creusen, D Dahlgren, M Hedeland, ... BMJ Open 12 (11), 2022 | | 2022 |
In vitro cell toxicity and intracellular uptake of doxorubicin exposed as a solution or liposomes: Implications for treatment of hepatocellular carcinoma F Kullenberg, O Degerstedt, C Calitz, N Pavlović, D Balgoma, J Gråsjö, ... Cells 10 (7), 1717, 2021 | 28 | 2021 |
A physiologically-based pharmacokinetic framework for prediction of drug exposure in malnourished children E Sjögren, J Tarning, KI Barnes, EN Jonsson Pharmaceutics 13 (2), 204, 2021 | 6 | 2021 |
Applications of physiologically based biopharmaceutics modeling (PBBM) to support drug product quality: a workshop summary report A Mitra, S Suarez-Sharp, XJH Pepin, T Flanagan, Y Zhao, E Kotzagiorgis, ... Journal of Pharmaceutical Sciences 110 (2), 594-609, 2021 | 36 | 2021 |
In vitro biopredictive methods: a workshop summary report XJH Pepin, J Dressman, N Parrott, P Delvadia, A Mitra, X Zhang, ... Journal of Pharmaceutical Sciences 110 (2), 567-583, 2021 | 22 | 2021 |
Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption (vol 22, 71, 2020) J Eriksson, E Sjogren, H Lennernas, H Thorn AAPS JOURNAL 23 (1), 2021 | 1 | 2021 |
Applications of Physiologically Based Biopharmaceutics Modeling (PBBM) to Support Drug Product Quality A Mitra, S Suarez-Sharp, XJH Pepin, T Flanagan, Y Zhao, E Kotzagiorgis, ... | | 2021 |
Correction to: Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption J Eriksson, E Sjögren, H Lennernäs, H Thörn The AAPS Journal 23 (1), 2021 | | 2021 |