Obesity shapes metabolism in the tumor microenvironment to suppress anti-tumor immunity AE Ringel, JM Drijvers, GJ Baker, A Catozzi, JC García-Cañaveras, ... Cell 183 (7), 1848-1866. e26, 2020 | 471 | 2020 |
Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass JB Spinelli, H Yoon, AE Ringel, S Jeanfavre, CB Clish, MC Haigis Science 358 (6365), 941-946, 2017 | 394 | 2017 |
Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity H Yoon, JL Shaw, MC Haigis, A Greka Molecular cell 81 (18), 3708-3730, 2021 | 216 | 2021 |
PHD3 loss in cancer enables metabolic reliance on fatty acid oxidation via deactivation of ACC2 NJ German, H Yoon, RZ Yusuf, JP Murphy, LWS Finley, G Laurent, ... Molecular cell 63 (6), 1006-1020, 2016 | 161 | 2016 |
mTOR and HDAC inhibitors converge on the TXNIP/thioredoxin pathway to cause catastrophic oxidative stress and regression of RAS-driven tumors CF Malone, C Emerson, R Ingraham, W Barbosa, S Guerra, H Yoon, ... Cancer Discovery 7 (12), 1450-1463, 2017 | 98 | 2017 |
Sirtuin 1 attenuates nasal polypogenesis by suppressing epithelial-to-mesenchymal transition M Lee, DW Kim, H Yoon, D So, R Khalmuratova, CS Rhee, JW Park, ... Journal of Allergy and Clinical Immunology 137 (1), 87-98. e7, 2016 | 75 | 2016 |
NAA10 controls osteoblast differentiation and bone formation as a feedback regulator of Runx2 H Yoon, HL Kim, YS Chun, DH Shin, KH Lee, CS Shin, DY Lee, HH Kim, ... Nature communications 5 (1), 5176, 2014 | 75 | 2014 |
Localized metabolomic gradients in patient-derived xenograft models of glioblastoma EC Randall, BGC Lopez, S Peng, MS Regan, WM Abdelmoula, SS Basu, ... Cancer research 80 (6), 1258-1267, 2020 | 73 | 2020 |
Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses H Yoon, SH Shin, DH Shin, YS Chun, JW Park Biochemical and biophysical research communications 444 (1), 36-43, 2014 | 65 | 2014 |
Antihepatoma activity of chaetocin due to deregulated splicing of hypoxia‐inducible factor 1α pre‐mRNA in mice and in vitro YM Lee, JH Lim, H Yoon, YS Chun, JW Park Hepatology 53 (1), 171-180, 2011 | 64 | 2011 |
Plant homeodomain finger protein 2 promotes bone formation by demethylating and activating Runx2 for osteoblast differentiation HJ Kim, JW Park, KH Lee, H Yoon, DH Shin, UI Ju, SH Seok, SH Lim, ... Cell research 24 (10), 1231-1249, 2014 | 59 | 2014 |
FIH is an oxygen sensor in ovarian cancer for G9a/GLP-driven epigenetic regulation of metastasis-related genes J Kang, SH Shin, H Yoon, J Huh, HW Shin, YS Chun, JW Park Cancer research 78 (5), 1184-1199, 2018 | 50 | 2018 |
CITED2 controls the hypoxic signaling by snatching p300 from the two distinct activation domains of HIF-1α H Yoon, JH Lim, CH Cho, LE Huang, JW Park Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (12), 2008-2016, 2011 | 49 | 2011 |
Arrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A SH Shin, H Yoon, YS Chun, HW Shin, MN Lee, GT Oh, JW Park Cell death & disease 5 (10), e1490-e1490, 2014 | 42 | 2014 |
SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis E Zaganjor, H Yoon, JB Spinelli, ER Nunn, G Laurent, P Keskinidis, ... Cell reports 36 (2), 2021 | 41 | 2021 |
Small-molecule screen identifies de novo nucleotide synthesis as a vulnerability of cells lacking SIRT3 KNG Herrera, E Zaganjor, Y Ishikawa, JB Spinelli, H Yoon, JR Lin, ... Cell reports 22 (8), 1945-1955, 2018 | 36 | 2018 |
PHD3 loss promotes exercise capacity and fat oxidation in skeletal muscle H Yoon, JB Spinelli, E Zaganjor, SJ Wong, NJ German, EC Randall, ... Cell metabolism 32 (2), 215-228. e7, 2020 | 31 | 2020 |
Gamma-aminobutyric acid signaling in damage response, metabolism, and disease K Kim, H Yoon International Journal of Molecular Sciences 24 (5), 4584, 2023 | 22 | 2023 |
Intrinsic myocardial defects underlie an Rbfox-deficient zebrafish model of hypoplastic left heart syndrome M Huang, AA Akerberg, X Zhang, H Yoon, S Joshi, C Hallinan, C Nguyen, ... Nature Communications 13 (1), 5877, 2022 | 15 | 2022 |
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity N Wieder, JC Fried, C Kim, EH Sidhom, MR Brown, JL Marshall, ... Cell metabolism 35 (5), 887-905. e11, 2023 | 13 | 2023 |