Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease JK Dennis, JM Sealock, P Straub, YH Lee, D Hucks, A Faucon, YCA Feng, ... Genome medicine 13 (1), 1-16, 2021 | 64 | 2021 |
Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization GA Pathak, K Singh, TW Miller-Fleming, FR Wendt, N Ehsan, K Hou, ... Nature communications 12 (1), 4569, 2021 | 63* | 2021 |
Use of the PsycheMERGE Network to Investigate the Association Between Depression Polygenic Scores and White Blood Cell Count JM Sealock, YH Lee, A Moscati, S Venkatesh, G Voloudakis, P Straub, ... JAMA psychiatry 78 (12), 1365-1374, 2021 | 29 | 2021 |
Pancreatic islet beta cell-specific deletion of G6pc2 reduces fasting blood glucose KJ Bosma, M Rahim, K Singh, SB Goleva, ML Wall, J Xia, KE Syring, ... Journal of molecular endocrinology 64 (4), 235-248, 2020 | 18 | 2020 |
Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits GA Pathak, K Singh, FR Wendt, TW Fleming, C Overstreet, D Koller, ... Molecular Psychiatry 27 (3), 1394-1404, 2022 | 17 | 2022 |
Characterizing the clinical and genetic spectrum of polycystic ovary syndrome in electronic health records KEV Actkins, K Singh, D Hucks, DR Velez Edwards, M Aldrich, J Cha, ... The Journal of Clinical Endocrinology & Metabolism 106 (1), 153-167, 2021 | 16 | 2021 |
Potential positive and negative consequences of ZnT8 inhibition KE Syring, KJ Bosma, SB Goleva, K Singh, JK Oeser, CA Lopez, ... Journal of Endocrinology 246 (2), 189-205, 2020 | 13 | 2020 |
Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose EM Overway, KJ Bosma, DP Claxton, JK Oeser, K Singh, LB Breidenbach, ... Journal of Biological Chemistry 298 (2), 2022 | 10 | 2022 |
Whole-exome sequencing in UK Biobank reveals rare genetic architecture for depression R Tian, T Ge, H Kweon, DB Rocha, M Lam, JZ Liu, K Singh, ... Nature Communications 15 (1), 1755, 2024 | 7* | 2024 |
Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabolic and Respiratory Outcomes GA Pathak, K Singh, KW Choi, Y Fang, MR Kouakou, YH Lee, X Zhou, ... JAMA psychiatry 81 (1), 34-44, 2024 | 5 | 2024 |
Transcriptome-wide structural equation modeling of 13 major psychiatric disorders for cross-disorder risk and drug repurposing AD Grotzinger, K Singh, TW Miller-Fleming, M Lam, TT Mallard, Y Chen, ... JAMA psychiatry 80 (8), 811-821, 2023 | 5* | 2023 |
The genetic architecture of plasma kynurenine includes cardiometabolic disease mechanisms associated with the SH2B3 gene M Bagheri, C Wang, M Shi, A Manouchehri, KT Murray, MB Murphy, ... Scientific reports 11 (1), 15652, 2021 | 4 | 2021 |
The genetic contribution to the comorbidity of depression and anxiety: a multi-site electronic health records study of almost 178 000 people BJ Coombes, I Landi, KW Choi, K Singh, B Fennessy, GD Jenkins, ... Psychological Medicine 53 (15), 7368-7374, 2023 | 3* | 2023 |
Sex-specific genetic and transcriptomic liability to neuroticism FR Wendt, GA Pathak, K Singh, MB Stein, KC Koenen, JH Krystal, ... Biological Psychiatry 93 (3), 243-252, 2023 | 3 | 2023 |
Genes associated with depression and coronary artery disease are enriched for cardiomyopathy and inflammatory phenotypes K Singh, H Lee, JM Sealock, T Miller-Fleming, P Straub, NJ Cox, QS Wells, ... Nature Mental Health, 1-9, 2024 | 1* | 2024 |
A higher genetic risk for depression is a greater risk factor for cardiovascular disease in women JC Jiang, K Singh, LK Davis, NR Wray, S Shah medRxiv, 2022 | 1 | 2022 |
Effects of sex and gender on the etiologies and presentation of select internalizing psychopathologies K Singh, FR Wendt Translational Psychiatry 14 (1), 73, 2024 | | 2024 |
Genome-wide study of major depression in 685,808 diverse individuals identifies 697 independent associations, infers causal neuronal subtypes and biological targets for novel … MJ Adams, ... medRxiv, 2024.04. 29.24306535, 2024 | | 2024 |
Investigating the Biology of Depression and Coronary Artery Disease using Genetics, Genomics, and Electronic Health Record Data K Singh | | 2023 |
W98. A PHENOME-WIDE ASSOCIATION STUDY OF POLYGENIC LIABILITY FOR EXTERNALIZING IN A EUROPEAN COHORT REVEALS SEX-SPECIFIC ASSOCIATIONS WITH NUMEROUS MEDICAL OUTCOMES N Courchesne-Krak, K Singh, AM Lake, M Jennings, J Meredith, ... European Neuropsychopharmacology 75, S156-S157, 2023 | | 2023 |