| Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk W Zhu, JC Gregory, E Org, JA Buffa, N Gupta, Z Wang, L Li, X Fu, Y Wu, ... Cell 165 (1), 111-124, 2016 | 1671 | 2016 |
| Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis Z Wang, AB Roberts, JA Buffa, BS Levison, W Zhu, E Org, X Gu, Y Huang, ... Cell 163 (7), 1585-1595, 2015 | 1220 | 2015 |
| Trimethylamine N‐oxide promotes vascular inflammation through signaling of mitogen‐activated protein kinase and nuclear factor‐κB MM Seldin, Y Meng, H Qi, WF Zhu, Z Wang, SL Hazen, AJ Lusis, DM Shih Journal of the American Heart Association 5 (2), e002767, 2016 | 734 | 2016 |
| Transmission of atherosclerosis susceptibility with gut microbial transplantation JC Gregory, JA Buffa, E Org, Z Wang, BS Levison, W Zhu, MA Wagner, ... Journal of Biological Chemistry 290 (9), 5647-5660, 2015 | 505 | 2015 |
| A cardiovascular disease-linked gut microbial metabolite acts via adrenergic receptors I Nemet, PP Saha, N Gupta, W Zhu, KA Romano, SM Skye, T Cajka, ... Cell 180 (5), 862-877. e22, 2020 | 448 | 2020 |
| Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential AB Roberts, X Gu, JA Buffa, AG Hurd, Z Wang, W Zhu, N Gupta, SM Skye, ... Nature medicine 24 (9), 1407-1417, 2018 | 438 | 2018 |
| Gut Microbiota–Dependent Trimethylamine N-Oxide Predicts Risk of Cardiovascular Events in Patients With Stroke and Is Related to Proinflammatory Monocytes A Haghikia, XS Li, TG Liman, N Bledau, D Schmidt, F Zimmermann, ... Arteriosclerosis, thrombosis, and vascular biology 38 (9), 2225-2235, 2018 | 260 | 2018 |
| Gut Microbe-Generated Trimethylamine N-Oxide From Dietary Choline Is Prothrombotic in Subjects W Zhu, Z Wang, WHW Tang, SL Hazen Circulation 135 (17), 1671-1673, 2017 | 250 | 2017 |
| Microbial transplantation with human gut commensals containing CutC is sufficient to transmit enhanced platelet reactivity and thrombosis potential SM Skye, W Zhu, KA Romano, CJ Guo, Z Wang, X Jia, J Kirsop, B Haag, ... Circulation research 123 (10), 1164-1176, 2018 | 137 | 2018 |
| The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity W Zhu, S Saddar, D Seetharam, KL Chambliss, C Longoria, DL Silver, ... Circulation research 102 (4), 480-487, 2008 | 137 | 2008 |
| Advanced glycation end products induce a prothrombotic phenotype in mice via interaction with platelet CD36 W Zhu, W Li, RL Silverstein Blood, The Journal of the American Society of Hematology 119 (25), 6136-6144, 2012 | 124 | 2012 |
| C-reactive protein downregulates endothelial NO synthase and attenuates reendothelialization in vivo in mice R Schwartz, S Osborne-Lawrence, L Hahner, LL Gibson, AK Gormley, ... Circulation research 100 (10), 1452-1459, 2007 | 118 | 2007 |
| Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N‐oxide‐generating pathway, modulates platelet responsiveness and thrombosis risk W Zhu, JA Buffa, Z Wang, M Warrier, R Schugar, DM Shih, N Gupta, ... Journal of Thrombosis and Haemostasis 16 (9), 1857-1872, 2018 | 117 | 2018 |
| Gut microbes impact stroke severity via the trimethylamine N-oxide pathway W Zhu, KA Romano, L Li, JA Buffa, N Sangwan, P Prakash, AN Tittle, ... Cell host & microbe 29 (7), 1199-1208. e5, 2021 | 91 | 2021 |
| Genetic Deficiency of Flavin-Containing Monooxygenase 3 (Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels—Brief Report DM Shih, W Zhu, RC Schugar, Y Meng, X Jia, A Miikeda, Z Wang, ... Arteriosclerosis, thrombosis, and vascular biology 39 (6), 1045-1054, 2019 | 46 | 2019 |
| The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota l-carnitine catabolism JA Buffa, KA Romano, MF Copeland, DB Cody, W Zhu, R Galvez, X Fu, ... Nature microbiology 7 (1), 73-86, 2022 | 43 | 2022 |
| Thrombin induces endothelial arginase through AP-1 activation W Zhu, UM Chandrasekharan, S Bandyopadhyay, SM Morris Jr, ... American Journal of Physiology-Cell Physiology 298 (4), C952-C960, 2010 | 43 | 2010 |
| Coupling of Fcγ receptor I to Fcγ receptor IIb by SRC kinase mediates C-reactive protein impairment of endothelial function NC Sundgren, W Zhu, IS Yuhanna, KL Chambliss, M Ahmed, K Tanigaki, ... Circulation research 109 (10), 1132-1140, 2011 | 35 | 2011 |
| Arginase blockade lessens endothelial dysfunction after thrombosis C Lewis, W Zhu, ML Pavkov, CM Kinney, PE DiCorleto, VS Kashyap Journal of vascular surgery 48 (2), 441-446, 2008 | 20 | 2008 |
| Techniques to harvest diseased human peripheral arteries and measure endothelial function in an ex vivo model RO Lakin, W Zhu, L Feiten, VS Kashyap Journal of vascular surgery 58 (2), 470-477, 2013 | 12 | 2013 |
