Role of RUNX1 in hematological malignancies R Sood, Y Kamikubo, P Liu Blood, The Journal of the American Society of Hematology 129 (15), 2070-2082, 2017 | 466 | 2017 |
Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples K Kumano, S Arai, M Hosoi, K Taoka, N Takayama, M Otsu, G Nagae, ... Blood, The Journal of the American Society of Hematology 119 (26), 6234-6242, 2012 | 191 | 2012 |
Genetic regulation of the RUNX transcription factor family has antitumor effects K Morita, K Suzuki, S Maeda, A Matsuo, Y Mitsuda, C Tokushige, ... The Journal of clinical investigation 127 (7), 2815-2828, 2017 | 119 | 2017 |
Inhibition of cell growth by conditional expression of kpm, a human homologue of Drosophila warts/lats tumor suppressor Y Kamikubo, A Takaori-Kondo, T Uchiyama, T Hori Journal of Biological Chemistry 278 (20), 17609-17614, 2003 | 83 | 2003 |
Molecular cloning of a novel human protein kinase, kpm, that is homologous to warts/lats, a Drosophila tumor suppressor T Hori, A Takaori-Kondo, Y Kamikubo, T Uchiyama Oncogene 19 (27), 3101-3109, 2000 | 76 | 2000 |
KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice L Zhao, JJ Melenhorst, L Alemu, M Kirby, S Anderson, M Kench, ... Blood, The Journal of the American Society of Hematology 119 (6), 1511-1521, 2012 | 62 | 2012 |
Accelerated leukemogenesis by truncated CBFβ-SMMHC defective in high-affinity binding with RUNX1 Y Kamikubo, L Zhao, M Wunderlich, T Corpora, RK Hyde, TA Paul, ... Cancer cell 17 (5), 455-468, 2010 | 57 | 2010 |
Modeling ASXL1 mutation revealed impaired hematopoiesis caused by derepression of p16Ink4a through aberrant PRC1-mediated histone modification M Uni, Y Masamoto, T Sato, Y Kamikubo, S Arai, E Hara, M Kurokawa Leukemia 33 (1), 191-204, 2019 | 51 | 2019 |
Cbfb/Runx1 repression–independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11 RK Hyde, Y Kamikubo, S Anderson, M Kirby, L Alemu, L Zhao, PP Liu Blood, The Journal of the American Society of Hematology 115 (7), 1433-1443, 2010 | 50 | 2010 |
Adverse prognostic impact of KIT mutations in childhood CBF-AML: the results of the Japanese Pediatric Leukemia/Lymphoma Study Group AML-05 trial M Tokumasu, C Murata, A Shimada, K Ohki, Y Hayashi, AM Saito, ... Leukemia 29 (12), 2438-2441, 2015 | 48 | 2015 |
RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells Y Mitsuda, K Morita, G Kashiwazaki, J Taniguchi, T Bando, M Obara, ... Scientific reports 8 (1), 6423, 2018 | 36 | 2018 |
Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells K Morita, M Noura, C Tokushige, S Maeda, H Kiyose, G Kashiwazaki, ... Scientific reports 7 (1), 16604, 2017 | 36 | 2017 |
Enhancement of neutrophil autophagy by an IVIG preparation against multidrug-resistant bacteria as well as drug-sensitive strains H Itoh, H Matsuo, N Kitamura, S Yamamoto, T Higuchi, H Takematsu, ... Journal of Leucocyte Biology 98 (1), 107-117, 2015 | 34 | 2015 |
Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19ARF N Nishimoto, S Arai, M Ichikawa, M Nakagawa, S Goyama, K Kumano, ... Blood, The Journal of the American Society of Hematology 118 (9), 2541-2550, 2011 | 34 | 2011 |
Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples M Hosoi, K Kumano, K Taoka, S Arai, K Kataoka, K Ueda, Y Kamikubo, ... Experimental hematology 42 (9), 816-825, 2014 | 28 | 2014 |
Recurrent CCND3 mutations in MLL-rearranged acute myeloid leukemia H Matsuo, K Yoshida, K Fukumura, K Nakatani, Y Noguchi, S Takasaki, ... Blood Advances 2 (21), 2879-2889, 2018 | 26 | 2018 |
Genetic compensation of RUNX family transcription factors in leukemia Y Kamikubo Cancer science 109 (8), 2358-2363, 2018 | 26 | 2018 |
Intravenous immunoglobulin enhances the killing activity and autophagy of neutrophils isolated from immunocompromised patients against multidrug-resistant bacteria H Matsuo, H Itoh, N Kitamura, Y Kamikubo, T Higuchi, S Shiga, ... Biochemical and Biophysical Research Communications 464 (1), 94-99, 2015 | 24 | 2015 |
RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice K Morita, C Tokushige, S Maeda, H Kiyose, M Noura, A Iwai, M Yamada, ... Blood Advances 2 (5), 509-515, 2018 | 21 | 2018 |
Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions K Morita, S Maeda, K Suzuki, H Kiyose, J Taniguchi, PP Liu, H Sugiyama, ... Blood Advances 1 (18), 1440-1451, 2017 | 20 | 2017 |