| Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors SRJ Hoare Drug discovery today 10 (6), 417-427, 2005 | 456 | 2005 |
| TIP39: a new neuropeptide and PTH2-receptor agonist from hypothalamus TB Usdin, SRJ Hoare, T Wang, E Mezey, JA Kowalak Nature neuroscience 2 (11), 941, 1999 | 239 | 1999 |
| The regulation of feeding and metabolic rate and the prevention of murine cancer cachexia with a small-molecule melanocortin-4 receptor antagonist S Markison, AC Foster, C Chen, GB Brookhart, A Hesse, SRJ Hoare, ... Endocrinology 146 (6), 2766-2773, 2005 | 103 | 2005 |
| Evaluating the signal transduction mechanism of the parathyroid hormone 1 receptor: effect of receptor-G-protein interaction on the ligand binding mechanism and receptor … SRJ Hoare, TJ Gardella, TB Usdin Journal of Biological Chemistry, 2000 | 100 | 2000 |
| Ligand affinity for amino-terminal and juxtamembrane domains of the corticotropin releasing factor type I receptor: regulation by G-protein and nonpeptide antagonists SRJ Hoare, SK Sullivan, DA Schwarz, N Ling, WW Vale, PD Crowe, ... Biochemistry 43 (13), 3996-4011, 2004 | 98 | 2004 |
| Pharmacologic characterization of valbenazine (NBI-98854) and its metabolites DE Grigoriadis, E Smith, SRJ Hoare, A Madan, H Bozigian Journal of Pharmacology and Experimental Therapeutics 361 (3), 454-461, 2017 | 79 | 2017 |
| Mechanism of corticotropin-releasing factor type I receptor regulation by nonpeptide antagonists SRJ Hoare, SK Sullivan, N Ling, PD Crowe, DE Grigoriadis Molecular pharmacology 63 (3), 751-765, 2003 | 79 | 2003 |
| Molecular mechanisms of ligand recognition by parathyroid hormone 1 (PTH1) and PTH2 receptors. SRJ Hoare, TB Usdin Current pharmaceutical design 7 (8), 689-713, 2001 | 79 | 2001 |
| Distinct conformations of the corticotropin releasing factor type 1 receptor adopted following agonist and antagonist binding are differentially regulated SJ Perry, S Junger, TA Kohout, SRJ Hoare, RS Struthers, DE Grigoriadis, ... Journal of Biological Chemistry 280 (12), 11560-11568, 2005 | 78 | 2005 |
| Molecular Determinants of Tuberoinfundibular Peptide of 39 Residues (TIP39) Selectivity for the Parathyroid Hormone-2 (PTH2) Receptor N-TERMINAL TRUNCATION OF TIP39 REVERSES … SRJ Hoare, JA Clark, TB Usdin Journal of Biological Chemistry 275 (35), 27274-27283, 2000 | 70 | 2000 |
| Comparison of rat and human parathyroid hormone 2 (PTH2) receptor activation: PTH is a low potency partial agonist at the rat PTH2 receptor SRJ Hoare, TI Bonner, TB Usdin Endocrinology 140 (10), 4419-4425, 1999 | 69 | 1999 |
| Binding kinetics redefine the antagonist pharmacology of the corticotropin-releasing factor type 1 receptor BA Fleck, SRJ Hoare, RR Pick, MJ Bradbury, DE Grigoriadis Journal of Pharmacology and Experimental Therapeutics 341 (2), 518-531, 2012 | 68 | 2012 |
| Peptide ligand binding properties of the corticotropin-releasing factor (CRF) type 2 receptor: pharmacology of endogenously expressed receptors, G-protein-coupling sensitivity … SRJ Hoare, SK Sullivan, J Fan, K Khongsaly, DE Grigoriadis Peptides 26 (3), 457-470, 2005 | 67 | 2005 |
| The parathyroid hormone 2 (PTH2) receptor TB Usdin, TI Bonner, SRJ Hoare Receptors and Channels 8 (3-4), 211-218, 2002 | 66 | 2002 |
| Functional selectivity of melanocortin 4 receptor peptide and nonpeptide agonists: evidence for ligand-specific conformational states SA Nickolls, B Fleck, SRJ Hoare, RA Maki Journal of Pharmacology and Experimental Therapeutics 313 (3), 1281-1288, 2005 | 59 | 2005 |
| Design and synthesis of tricyclic corticotropin-releasing factor-1 antagonists RS Gross, Z Guo, B Dyck, T Coon, CQ Huang, RF Lowe, D Marinkovic, ... Journal of medicinal chemistry 48 (18), 5780-5793, 2005 | 58 | 2005 |
| Regulation of D2 dopamine receptors by amiloride and amiloride analogs. SR Hoare, PG Strange Molecular pharmacology 50 (5), 1295-1308, 1996 | 58 | 1996 |
| Evaluating the ligand specificity of zebrafish parathyroid hormone (PTH) receptors: comparison of PTH, PTH-related protein, and tuberoinfundibular peptide of 39 residues SRJ Hoare, DA Rubin, H Jüppner, TB Usdin Endocrinology 141 (9), 3080-3086, 2000 | 56 | 2000 |
| Drugability of extracellular targets: discovery of small molecule drugs targeting allosteric, functional, and subunit-selective sites on GPCRs and ion channels DE Grigoriadis, SRJ Hoare, SM Lechner, DH Slee, JA Williams Neuropsychopharmacology 34 (1), 106-125, 2009 | 55 | 2009 |
| The discovery and structure–activity relationships of 2-(piperidin-3-yl)-1H-benzimidazoles as selective, CNS penetrating H1-antihistamines for insomnia K Lavrador-Erb, SB Ravula, J Yu, S Zamani-Kord, WJ Moree, RE Petroski, ... Bioorganic & medicinal chemistry letters 20 (9), 2916-2919, 2010 | 47 | 2010 |
