| Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations W Albrecht, F Kappenberg, T Brecklinghaus, R Stoeber, R Marchan, ... Archives of toxicology 93, 1609-1637, 2019 | 100 | 2019 |
| Long-term prognostic significance of HER2-low and HER2-zero in node-negative breast cancer K Almstedt, AS Heimes, F Kappenberg, MJ Battista, HA Lehr, S Krajnak, ... European Journal of Cancer 173, 10-19, 2022 | 53 | 2022 |
| Relevance of the incubation period in cytotoxicity testing with primary human hepatocytes X Gu, W Albrecht, K Edlund, F Kappenberg, J Rahnenführer, M Leist, ... Archives of toxicology 92, 3505-3515, 2018 | 49 | 2018 |
| Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity A Ghallab, R Hassan, U Hofmann, A Friebel, Z Hobloss, L Brackhagen, ... Journal of Hepatology 77 (1), 71-83, 2022 | 37 | 2022 |
| Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression A Ghallab, M Myllys, A Friebel, J Duda, K Edlund, E Halilbasic, M Vucur, ... Cells 10 (10), 2516, 2021 | 29 | 2021 |
| Determination of benchmark concentrations and their statistical uncertainty for cytotoxicity test data and functional in vitro assays A Krebs, J Nyffeler, C Karreman, BZ Schmidt, F Kappenberg, J Mellert, ... | 24 | 2020 |
| The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds T Brecklinghaus, W Albrecht, F Kappenberg, J Duda, N Vartak, K Edlund, ... Chemico-Biological Interactions 351, 109728, 2022 | 19 | 2022 |
| Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis A Ghallab, D González, E Strängberg, U Hofmann, M Myllys, R Hassan, ... Journal of hepatology 80 (2), 268-281, 2024 | 9 | 2024 |
| Discordance of HER2-low between primary tumors and matched distant metastases in breast cancer K Almstedt, L Krauthauser, F Kappenberg, DC Wagner, AS Heimes, ... Cancers 15 (5), 1413, 2023 | 8 | 2023 |
| Comparison of observation-based and model-based identification of alert concentrations from concentration–expression data F Kappenberg, M Grinberg, X Jiang, A Kopp-Schneider, JG Hengstler, ... Bioinformatics 37 (14), 1990-1996, 2021 | 8 | 2021 |
| Handling deviating control values in concentration-response curves F Kappenberg, T Brecklinghaus, W Albrecht, J Blum, C van der Wurp, ... Archives of toxicology 94 (11), 3787-3798, 2020 | 8 | 2020 |
| Identifying alert concentrations using a model‐based bootstrap approach K Möllenhoff, K Schorning, F Kappenberg Biometrics 79 (3), 2076-2088, 2023 | 4 | 2023 |
| Model selection characteristics when using MCP‐Mod for dose–response gene expression data JC Duda, F Kappenberg, J Rahnenführer Biometrical Journal 64 (5), 883-897, 2022 | 4 | 2022 |
| Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test A Cherianidou, F Seidel, F Kappenberg, N Dreser, J Blum, T Waldmann, ... Chemical Research in Toxicology 35 (5), 760-773, 2022 | 4 | 2022 |
| In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay T Brecklinghaus, W Albrecht, J Duda, F Kappenberg, L Gründler, ... Toxicology Letters 368, 33-46, 2022 | 3 | 2022 |
| High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation F Seidel, A Cherianidou, F Kappenberg, M Marta, N Dreser, J Blum, ... Cells 11 (21), 3404, 2022 | 3 | 2022 |
| Influence of bile acids on the cytotoxicity of chemicals in cultivated human hepatocytes T Brecklinghaus, W Albrecht, F Kappenberg, J Duda, M Zhang, I Gardner, ... Toxicology in Vitro 81, 105344, 2022 | 1 | 2022 |
| Benefit of using interaction effects for the analysis of high-dimensional time-response or dose-response data for two-group comparisons JC Duda, C Drenda, H Kästel, J Rahnenführer, F Kappenberg Scientific Reports 13 (1), 20804, 2023 | | 2023 |
| Classification of hepatotoxicity of compounds based on cytotoxicity assays is improved by additional interpretable summaries of high-dimensional gene expression data M Stolte, W Albrecht, T Brecklinghaus, L Gründler, P Chen, JG Hengstler, ... Computational Toxicology 28, 100288, 2023 | | 2023 |
| Information sharing in high-dimensional gene expression data for improved parameter estimation in concentration-response modelling F Kappenberg, J Rahnenführer PloS one 18 (10), e0293180, 2023 | | 2023 |
