Exploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer G Brahemi, FR Kona, A Fiasella, D Buac, J Soukupová, A Brancale, ... Journal of medicinal chemistry 53 (7), 2757-2765, 2010 | 172 | 2010 |
New insights into the crossroads between EMT and stemness in the context of cancer I Fabregat, A Malfettone, J Soukupova Journal of clinical medicine 5 (3), 37, 2016 | 153 | 2016 |
Transforming growth factor-β-induced plasticity causes a migratory stemness phenotype in hepatocellular carcinoma A Malfettone, J Soukupova, E Bertran, E Crosas-Molist, R Lastra, ... Cancer letters 392, 39-50, 2017 | 89 | 2017 |
Bcl3 selectively promotes metastasis of ERBB2-driven mammary tumors A Wakefield, J Soukupova, A Montagne, J Ranger, R French, WJ Muller, ... Cancer research 73 (2), 745-755, 2013 | 81 | 2013 |
Role of the Transforming Growth Factor-β in regulating hepatocellular carcinoma oxidative metabolism J Soukupova, A Malfettone, P Hyroššová, MI Hernández-Alvarez, ... Scientific Reports 7 (1), 12486, 2017 | 67 | 2017 |
TGF-β in hepatic stellate cell activation and liver fibrogenesis: updated B Dewidar, J Soukupova, I Fabregat, S Dooley Current pathobiology reports 3, 291-305, 2015 | 48 | 2015 |
Epithelial–mesenchymal transition (Emt) induced by tgf-β in hepatocellular carcinoma cells reprograms lipid metabolism J Soukupova, A Malfettone, E Bertran, MI Hernández-Alvarez, ... International journal of molecular sciences 22 (11), 5543, 2021 | 37 | 2021 |
Galunisertib suppresses the staminal phenotype in hepatocellular carcinoma by modulating CD44 expression B Rani, A Malfettone, F Dituri, J Soukupova, L Lupo, S Mancarella, ... Cell Death & Disease 9 (3), 373, 2018 | 34 | 2018 |
Hybrid polymeric-protein nano-carriers (HPPNC) for targeted delivery of TGFβ inhibitors to hepatocellular carcinoma cells NAN Hanafy, A Quarta, R Di Corato, L Dini, C Nobile, V Tasco, S Carallo, ... Journal of Materials Science: Materials in Medicine 28, 1-11, 2017 | 34 | 2017 |
Resminostat induces changes in epithelial plasticity of hepatocellular carcinoma cells and sensitizes them to sorafenib-induced apoptosis J Soukupova, E Bertran, I Peñuelas-Haro, U Urdiroz-Urricelqui, ... Oncotarget 8 (66), 110367, 2017 | 32 | 2017 |
The discovery of a novel antimetastatic Bcl3 inhibitor J Soukupová, C Bordoni, DJ Turnham, WW Yang, G Seaton, A Gruca, ... Molecular Cancer Therapeutics 20 (5), 775-786, 2021 | 14 | 2021 |
Crosstalk between TGF-B-Induced Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma A Malfettone, J Soukupova, J Fernando, P Koudelkova, E Bertran, ... Journal of Hepatology 2 (64), S557, 2016 | 3 | 2016 |
2-benzoylaminobenzamide derivatives as Bcl-3 inhibitors AD Westwell, A Brancale, RWE Clarkson, J Soukupova US Patent 10,450,285, 2019 | 1 | 2019 |
Molecular modelling in anticancer drug design: the discovery of the BCL3 inhibitors AB Le, J Soukupova, A Westwell, R Clarkson ANTICANCER RESEARCH 35 (7), 4294-4294, 2015 | 1 | 2015 |
2-benzoylaminobenzamide derivatives as bcl-3 inhibitors AD Westwell, A Brancale, RWE Clarkson, J Soukupova US Patent App. 17/488,568, 2022 | | 2022 |
Resminostat sensitizes hepatocellular carcinoma cells to sorafenib-induced cell death J Soukupova, UU Urricelqui, M Borgmann, H Kohlhof, I Fabregat European Journal of Cancer 1 (69), S87, 2016 | | 2016 |
New insights into the crossroads between EMT and stemness in the context of cancer I Fabregat Romero, A Malfettone, J Soukupova Journal of Clinical Medicine, 2016, vol. 5, num. 3, p. 37, 2016 | | 2016 |
DESIGNING DRUGS TO TACKLE UNMET MEDICAL NEED IN BREAST CANCER A Brancale, J Soukupova, RWE Clarkson, AD Westwell ANTICANCER RESEARCH 35 (7), 4321-4322, 2015 | | 2015 |
2-benzoylaminobenzamide derivatives as bcl-3 inhibitors AD Westwell, A Brancale, RWE Clarkson, J Soukupova | | 2015 |
P0297: The transforming growth factor-beta (TGF-β) governs human liver tumor cell plasticity A Malfettone, J Fernando, P Koudelkova, J Soukupova, E Bertran, ... Journal of Hepatology, S419-S420, 2015 | | 2015 |